2026 ICD-10-CM Diagnosis Code D65Disseminated intravascular coagulation [defibrination syndrome]

ICD-10-CM Codes›D50–D89›D65-D69›D65

ICD-10-CM D65
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D65 is a billable ICD-10-CM diagnosis code for disseminated intravascular coagulation [defibrination syndrome]. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coagulation and hemorrhagic disorders.

Code Identity

ICD-10-CM Code
D65
Billable Status
Yes — Valid for Submission
Code Describes
Disseminated intravascular coagulation [defibrination syndrome]
Chapter
D65-D69
Coagulation defects, purpura and other hemorrhagic conditions

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD65-D69Coagulation defects, purpura and other hemorrhagic conditions
CategoryD65Disseminated intravascular coagulation [defibrination syndrome]
This CodeD65Disseminated intravascular coagulation [defibrination syndrome]

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal fibrinolysis
  • Acquired afibrinogenemia
  • Acquired fibrinogen abnormality
  • Acquired purpura fulminans
  • Afibrinogenemia
  • Consumption coagulopathy caused by snake venom
  • Disseminated intravascular coagulation
  • Drug-induced fibrinolytic disorder
  • Fibrinolytic bleeding syndrome
  • Fibrinolytic disorder caused by tissue plasminogen activator
  • Fibrinolytic disorder caused by urokinase
  • Hyperfibrinolysis
  • Increased fibrinolysis
  • Purpura fulminans
  • Secondary non-thrombocytopenic purpura
  • Systemic fibrinogenolysis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Afibrinogenemia, acquired
  • Consumption coagulopathy
  • COVID-19 associated diffuse or disseminated intravascular coagulopathy
  • Diffuse or disseminated intravascular coagulation DIC
  • Fibrinolytic hemorrhage, acquired
  • Fibrinolytic purpura
  • Purpura fulminans

Code Also

  • , if applicable, associated condition

Type 1 Excludes

  • disseminated intravascular coagulation (complicating):
  • abortion or ectopic or molar pregnancy O00 O07 O08.1
  • in newborn P60
  • pregnancy, childbirth and the puerperium O45.0 O46.0 O67.0 O72.3

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Absence(of) (organ or part) (complete or partial)
      • fibrinogen (congenital)
        • acquired
    • Afibrinogenemia
      • acquired
    • Coagulation, intravascular(diffuse) (disseminated)
      • COVID-19 associated
    • Coagulopathy
      • consumption
    • Coagulopathy
      • intravascular
    • Defibrination(syndrome)
    • Deficiency, deficient
      • fibrinogen (congenital) (hereditary)
        • acquired
    • Disorder(of)
      • glomerular (in)
        • disseminated intravascular coagulation
    • Fibrinogenopenia
      • acquired
    • Fibrinolysis(hemorrhagic) (acquired)
    • Glomerulonephritis
      • in (due to)
        • defibrination syndrome
    • Glomerulonephritis
      • in (due to)
        • disseminated intravascular coagulation
    • Hypofibrinogenemia
      • acquired
    • Proteolysis, pathologic
    • Purpura
      • fulminans, fulminous
    • Purpura
      • gangrenous
    • Syndrome
      • DIC (diffuse or disseminated intravascular coagulopathy)
    • Syndrome
      • ICF (intravascular coagulation-fibrinolysis)
    • Syndrome
      • intravascular coagulation-fibrinolysis (ICF)
    • Syndrome
      • IVC (intravascular coagulopathy)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD006
Coagulation and hemorrhagic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Disseminated Intravascular Coagulation

    a disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. the activation of the clotting mechanism may arise from any of a number of disorders. a majority of the patients manifest skin lesions, sometimes leading to purpura fulminans.

  • Purpura Fulminans

    a severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. it is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. purpura fulminans often accompanies or is triggered by disseminated intravascular coagulation.

  • Waterhouse-Friderichsen Syndrome

    a condition of hemorrhage and necrosis of the adrenal gland. it is characterized by rapidly developing adrenal insufficiency; hypotension; and widespread cutaneous purpura.

  • Afibrinogenemia

    a deficiency or absence of fibrinogen in the blood.

  • Fibrinogen

    plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides a and b, the proteolytic action of other enzymes yields different fibrinogen degradation products.

  • Afibrinogenemia

    a blood coagulation disorder characterized by the complete absence of fibrinogen in the blood, resulting in bleeding.

Patient EducationClinical

Bleeding Disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D65 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
286.6 Defibrination syndrome
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D65Overview

Is D65 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report disseminated intravascular coagulation [defibrination syndrome] on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of D65?

Under the General Equivalence Mappings, disseminated intravascular coagulation [defibrination syndrome] converts to ICD-9-CM 286.6 (defibrination syndrome). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.