2026 ICD-10-CM Diagnosis Code D64.2Secondary sideroblastic anemia due to drugs and toxins
ICD-10-CM Codes›D50–D89›D60-D64›D64
- Billable — Valid for Submission
- Not Chronic
D64.2 is a billable ICD-10-CM diagnosis code for secondary sideroblastic anemia due to drugs and toxins. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 811 through 812. Coders also document this condition as alcohol-related sideroblastic anemia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Aplastic anemia and Drug induced or toxic related condition.
D64.2 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 48 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 48, ESRD (V21) category 48, ESRD (V24) category 48, and RxHCC Part D (V08) category 96 for payment year 2026.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
D64.2 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.
Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Alcohol-related sideroblastic anemia
- Anemia caused by lead
- Drug-induced sideroblastic anemia
- Secondary acquired sideroblastic anemia
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Code First
Use Additional Code
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Anemia
If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D64.2 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D64.2Overview
What is the ICD-10 code for secondary sideroblastic anemia due to drugs and toxins?
The ICD-10-CM code for secondary sideroblastic anemia due to drugs and toxins is D64.2 (sometimes written as D642). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Is D64.2 (Other anemias) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report secondary sideroblastic anemia due to drugs and toxins on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does D64.2 group to?
When secondary sideroblastic anemia due to drugs and toxins is the principal diagnosis on an inpatient stay, it groups to MS-DRG 811, 812, with relative weights from 0.9182 to 1.4043 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of D64.2?
Under the General Equivalence Mappings, secondary sideroblastic anemia due to drugs and toxins converts to ICD-9-CM 285.0 (sideroblastic anemia). The mapping is approximate, so confirm the match fits the documentation.
Does D64.2 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage. D64.2 mapped to HCC 48 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 48 (Coagulation Defects and Other Specified Hematological Disorders), ESRD (V21) category 48 (Coagulation Defects and Other Specified Hematological Disorders), ESRD (V24) category 48 (Coagulation Defects and Other Specified Hematological Disorders), and RxHCC Part D (V08) category 96 (Acquired Hemolytic, Aplastic, and Sideroblastic Anemias).
