ICD-10-CM Code D64.9

Anemia, unspecified

Version 2020 Billable Code

Valid for Submission

D64.9 is a billable code used to specify a medical diagnosis of anemia, unspecified. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code D64.9 might also be used to specify conditions or terms like anemia, anemia caused by zidovudine, anemia co-occurrent and due to chronic kidney disease stage 3, anemia co-occurrent with human immunodeficiency virus infection, anemia due to multiple mechanisms, anemia due to unknown mechanism, etc

Short Description:Anemia, unspecified
Long Description:Anemia, unspecified

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D64.9 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Anemia
  • Anemia caused by zidovudine
  • Anemia co-occurrent and due to chronic kidney disease stage 3
  • Anemia co-occurrent with human immunodeficiency virus infection
  • Anemia due to multiple mechanisms
  • Anemia due to unknown mechanism
  • Anemia in chronic kidney disease
  • Anemia in mother complicating childbirth
  • Anemia of chronic disease
  • Anemia of renal disease
  • Central nervous system calcification, deafness, tubular acidosis, anemia syndrome
  • Chronic anemia
  • Hemoglobin low
  • Normocytic normochromic anemia
  • O/E - anemia
  • O/E - clinically anemic
  • O/E - equivocally anemic
  • O/E - profoundly anemic
  • Pericarditis associated with severe chronic anemia
  • Relative anemia

Clinical Information

  • ANEMIA-. a reduction in the number of circulating erythrocytes or in the quantity of hemoglobin.
  • ANEMIA APLASTIC-. a form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.
  • ANEMIA DYSERYTHROPOIETIC CONGENITAL-. a familial disorder characterized by anemia with multinuclear erythroblasts karyorrhexis asynchrony of nuclear and cytoplasmic maturation and various nuclear abnormalities of bone marrow erythrocyte precursors erythroid precursor cells. type ii is the most common of the 3 types; it is often referred to as hempas based on the hereditary erythroblast multinuclearity with positive acidified serum test.
  • ANEMIA HEMOLYTIC-. a condition of inadequate circulating red blood cells anemia or insufficient hemoglobin due to premature destruction of red blood cells erythrocytes.
  • ANEMIA HEMOLYTIC AUTOIMMUNE-. acquired hemolytic anemia due to the presence of autoantibodies which agglutinate or lyse the patient's own red blood cells.
  • ANEMIA HEMOLYTIC CONGENITAL-. hemolytic anemia due to various intrinsic defects of the erythrocyte.
  • ANEMIA HEMOLYTIC CONGENITAL NONSPHEROCYTIC-. any one of a group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. common causes include deficiencies in glucose 6 phosphate isomerase; pyruvate kinase; and glucose 6 phosphate dehydrogenase.
  • ANEMIA HYPOCHROMIC-. anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte i.e. the mean corpuscular hemoglobin concentration is less than normal. the individual cells contain less hemoglobin than they could have under optimal conditions. hypochromic anemia may be caused by iron deficiency from a low iron intake diminished iron absorption or excessive iron loss. it can also be caused by infections or other diseases therapeutic drugs lead poisoning and other conditions. stedman 25th ed; from miale laboratory medicine: hematology 6th ed p393
  • ANEMIA MACROCYTIC-. anemia characterized by larger than normal erythrocytes increased mean corpuscular volume mcv and increased mean corpuscular hemoglobin mch.
  • ANEMIA MEGALOBLASTIC-. a disorder characterized by the presence of anemia abnormally large red blood cells megalocytes or macrocytes and megaloblasts.
  • ANEMIA MYELOPHTHISIC-. anemia characterized by appearance of immature myeloid and nucleated erythrocytes in the peripheral blood resulting from infiltration of the bone marrow by foreign or abnormal tissue.
  • ANEMIA NEONATAL-. the mildest form of erythroblastosis fetalis in which anemia is the chief manifestation.
  • ANEMIA PERNICIOUS-. a megaloblastic anemia occurring in children but more commonly in later life characterized by histamine fast achlorhydria in which the laboratory and clinical manifestations are based on malabsorption of vitamin b 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. dorland 27th ed
  • ANEMIA REFRACTORY-. a severe sometimes chronic anemia usually macrocytic in type that does not respond to ordinary antianemic therapy.
  • ANEMIA REFRACTORY WITH EXCESS OF BLASTS-. chronic refractory anemia with granulocytopenia and/or thrombocytopenia. myeloblasts and progranulocytes constitute 5 to 40 percent of the nucleated marrow cells.
  • ANEMIA SICKLE CELL-. a disease characterized by chronic hemolytic anemia episodic painful crises and pathologic involvement of many organs. it is the clinical expression of homozygosity for hemoglobin s.
  • ANEMIA SIDEROBLASTIC-. anemia characterized by the presence of erythroblasts containing excessive deposits of iron in the marrow.
  • EQUINE INFECTIOUS ANEMIA-. viral disease of horses caused by the equine infectious anemia virus eiav; infectious anemia virus equine. it is characterized by intermittent fever weakness and anemia. chronic infection consists of acute episodes with remissions.
  • FANCONI ANEMIA-. congenital disorder affecting all bone marrow elements resulting in anemia; leukopenia; and thrombopenia and associated with cardiac renal and limb malformations as well as dermal pigmentary changes. spontaneous chromosome breakage is a feature of this disease along with predisposition to leukemia. there are at least 7 complementation groups in fanconi anemia: fanca fancb fancc fancd1 fancd2 fance fancf fancg and fancl. from online mendelian inheritance in man http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650 august 20 2004
  • HYPERSPLENISM-. condition characterized by splenomegaly some reduction in the number of circulating blood cells in the presence of a normal or hyperactive bone marrow and the potential for reversal by splenectomy.
  • BETA THALASSEMIA-. a disorder characterized by reduced synthesis of the beta chains of hemoglobin. there is retardation of hemoglobin a synthesis in the heterozygous form thalassemia minor which is asymptomatic while in the homozygous form thalassemia major cooley's anemia mediterranean anemia erythroblastic anemia which can result in severe complications and even death hemoglobin a synthesis is absent.
  • ANEMIA IRON DEFICIENCY-. anemia characterized by decreased or absent iron stores low serum iron concentration low transferrin saturation and low hemoglobin concentration or hematocrit value. the erythrocytes are hypochromic and microcytic and the iron binding capacity is increased.
  • ANEMIA HYPOPLASTIC CONGENITAL-. an inborn condition characterized by deficiencies of red cell precursors that sometimes also includes leukopenia and thrombocytopenia.
  • ANEMIA DIAMOND BLACKFAN-. a rare congenital hypoplastic anemia that usually presents early in infancy. the disease is characterized by a moderate to severe macrocytic anemia occasional neutropenia or thrombocytosis a normocellular bone marrow with erythroid hypoplasia and an increased risk of developing leukemia. curr opin hematol 2000 mar;72:85 94

Diagnostic Related Groups

The ICD-10 code D64.9 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2019 through 09/30/2020.


Convert D64.9 to ICD-9

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)
    • Aplastic and other anemias and other bone marrow failure syndromes (D60-D64)
      • Other anemias (D64)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include

  • Heavy periods
  • Pregnancy
  • Ulcers
  • Colon polyps or colon cancer
  • Inherited disorders
  • A diet that does not have enough iron, folic acid or vitamin B12
  • Blood disorders such as sickle cell anemia and thalassemia, or cancer
  • Aplastic anemia, a condition that can be inherited or acquired
  • G6PD deficiency, a metabolic disorder

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute

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