2026 ICD-10-CM Diagnosis Code T65Toxic effect of other and unspecified substances

ICD-10-CM Codes›S00–T88›T51-T65›T65

ICD-10-CM T65
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T65 is a non-billable ICD-10-CM category code for toxic effect of other and unspecified substances, so it cannot be submitted on claims. Use a more specific code from this category instead, such as T65.0X1A, T65.0X1D, T65.0X1S, and T65.0X2A.

Code Identity

ICD-10-CM Code
T65
Billable Status
No — Non-Billable Category
Code Describes
Toxic effect of other and unspecified substances
Chapter
T51-T65
Toxic effects of substances chiefly nonmedicinal as to source

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT51-T65Toxic effects of substances chiefly nonmedicinal as to source
CategoryT65Toxic effect of other and unspecified substances
This CodeT65Toxic effect of other and unspecified substances

Specific Coding for Toxic effect of other and unspecified substancesOverview

Non-specific codes like T65 require more characters. Use one of these billable codes instead:

  • T65.0 for Toxic effect of cyanides

  • T65.0X for Toxic effect of cyanides

  • T65.1 for Toxic effect of strychnine and its salts

  • T65.1X for Toxic effect of strychnine and its salts

  • T65.2 for Toxic effect of tobacco and nicotine

  • T65.21 for Toxic effect of chewing tobacco

  • T65.22 for Toxic effect of tobacco cigarettes

  • T65.29 for Toxic effect of other tobacco and nicotine

  • T65.3 for Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues

  • T65.3X for Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues

  • T65.4 for Toxic effect of carbon disulfide

  • T65.4X for Toxic effect of carbon disulfide

  • T65.5 for Toxic effect of nitroglycerin and other nitric acids and esters

  • T65.5X for Toxic effect of nitroglycerin and other nitric acids and esters

  • T65.6 for Toxic effect of paints and dyes, not elsewhere classified

  • T65.6X for Toxic effect of paints and dyes, not elsewhere classified

  • T65.8 for Toxic effect of other specified substances

  • T65.81 for Toxic effect of latex

  • T65.82 for Toxic effect of harmful algae and algae toxins

  • T65.83 for Toxic effect of fiberglass

  • T65.84 for Toxic effect of xylazine

  • T65.89 for Toxic effect of other specified substances

  • T65.9 for Toxic effect of unspecified substance

  • T65.91 for Toxic effect of unspecified substance, accidental (unintentional)

  • T65.92 for Toxic effect of unspecified substance, intentional self-harm

  • T65.93 for Toxic effect of unspecified substance, assault

  • T65.94 for Toxic effect of unspecified substance, undetermined

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Toxic effect of other and unspecified substances (T65). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

7th Character Note

  • The appropriate 7th character is to be added to each code from category T65

7th Character

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T65Overview

Is T65 (Toxic effect of other and unspecified substances) a billable code?

No. This is a category header that groups the codes for toxic effect of other and unspecified substances, and headers cannot be submitted on claims. Claims for toxic effect of other and unspecified substances need a more specific code from this category, such as T65.0X1A, T65.0X1D, and T65.0X1S.