Excludes2 Notes in Chapter 4: Endocrine, nutritional and metabolic diseases ICD-10-CM
An Excludes2 note means "NOT INCLUDED HERE": the excluded condition is not part of this code, but a patient may have both, so both codes may be reported. In Chapter 4 (E00-E89), notes printed in the chapter name other codes 37 times, and Excludes2 Notes anywhere in the Tabular List name the chapter’s codes 111 times, covering 70 distinct codes, categories and ranges. Switch views to read the list either way.
Excludes2 Notes by the code that carries the note
- familial hypocalciuric hypercalcemia (E83.52)
- E21.2 Other hyperparathyroidism
- familial hypocalciuric hypercalcemia (E83.52)
- E34.8 Other specified endocrine disorders
- pseudohypoparathyroidism (E20.1)
- postprocedural endocrine and metabolic complications and disorders, not elsewhere classified (E89.-)
- E53.8 Deficiency of other specified B group vitamins
- vitamin B12 deficiency anemia (D51.-)
- E64.0 Sequelae of protein-calorie malnutrition
- retarded development following protein-calorie malnutrition (E45)
- Ehlers-Danlos syndromes (Q79.6-)
- carnitine deficiency due to inborn error of metabolism (E71.42)
- lactose intolerance (E73.-)
- disorders of pyrophosphate metabolism (E83.82-)
- Alzheimer's disease (G30.0-)
- E85.0 Non-neuropathic heredofamilial amyloidosis
- Transthyretin-related (ATTR) familial amyloid cardiomyopathy (E85.4)
- hypovolemic shock NOS (R57.1)
- E87.0 Hyperosmolality and hypernatremia
- E87.29 Other acidosis
- disorder of lipoprotein metabolism (E78.-)
- E88.A Wasting disease (syndrome) due to underlying condition
- E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified applies to 17 codes
- E00-E02 Congenital iodine-deficiency syndrome to Subclinical iodine-deficiency hypothyroidism 9 codes
- Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified: iodine-deficiency-related hypothyroidism (E00-E02)
- E00-E88 Congenital iodine-deficiency syndrome to Other and unspecified metabolic disorders 956 codes
- Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 6 (G00-G99) Diseases of the nervous system: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 7 (H00-H59) Diseases of the eye and adnexa: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 8 (H60-H95) Diseases of the ear and mastoid process: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 9 (I00-I99) Diseases of the circulatory system: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 10 (J00-J99) Diseases of the respiratory system: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 11 (K00-K95) Diseases of the digestive system: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 12 (L00-L99) Diseases of the skin and subcutaneous tissue: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 13 (M00-M99) Diseases of the musculoskeletal system and connective tissue: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 14 (N00-N99) Diseases of the genitourinary system: endocrine, nutritional and metabolic diseases (E00-E88)
- Chapter 16 (P00-P96) Certain conditions originating in the perinatal period: endocrine, nutritional and metabolic diseases (E00-E88)
- E08.311-E08.359 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy with macular edema to Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy without macular edema 50 codes
- H35 Other retinal disorders: diabetic retinal disorders (E08.311-E08.359, E09.311-E09.359, E10.311-E10.359, E11.311-E11.359, E13.311-E13.359)
- E08.43 Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy
- K31 Other diseases of stomach and duodenum: diabetic gastroparesis (E08.43, E09.43, E10.43, E11.43, E13.43)
- E08.621 Diabetes mellitus due to underlying condition with foot ulcer
- E08.622 Diabetes mellitus due to underlying condition with other skin ulcer
- L89 Pressure ulcer: diabetic ulcers (E08.621, E08.622, E09.621, E09.622, E10.621, E10.622, E11.621, E11.622, E13.621, E13.622)
- E08-E13 Diabetes mellitus due to underlying condition to Other specified diabetes mellitus 432 codes
- I96 Gangrene, not elsewhere classified: gangrene in diabetes mellitus (E08-E13 with .52)
- E09.311-E09.359 Drug or chemical induced diabetes mellitus with unspecified diabetic retinopathy with macular edema to Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy without macular edema 50 codes
- H35 Other retinal disorders: diabetic retinal disorders (E08.311-E08.359, E09.311-E09.359, E10.311-E10.359, E11.311-E11.359, E13.311-E13.359)
- Chapter 7 (H00-H59) Diseases of the eye and adnexa: diabetes mellitus related eye conditions (E09.3-, E10.3-, E11.3-, E13.3-)
- E09.43 Drug or chemical induced diabetes mellitus with neurological complications with diabetic autonomic (poly)neuropathy
- K31 Other diseases of stomach and duodenum: diabetic gastroparesis (E08.43, E09.43, E10.43, E11.43, E13.43)
- E09.621 Drug or chemical induced diabetes mellitus with foot ulcer
- E09.622 Drug or chemical induced diabetes mellitus with other skin ulcer
- L89 Pressure ulcer: diabetic ulcers (E08.621, E08.622, E09.621, E09.622, E10.621, E10.622, E11.621, E11.622, E13.621, E13.622)
- E87.0 Hyperosmolality and hypernatremia: diabetes with hyperosmolarity (E08, E09, E11, E13 with final characters .00 or .01)
- E10.311-E10.359 Type 1 diabetes mellitus with unspecified diabetic retinopathy with macular edema to Type 1 diabetes mellitus with proliferative diabetic retinopathy without macular edema 50 codes
- H35 Other retinal disorders: diabetic retinal disorders (E08.311-E08.359, E09.311-E09.359, E10.311-E10.359, E11.311-E11.359, E13.311-E13.359)
- Chapter 7 (H00-H59) Diseases of the eye and adnexa: diabetes mellitus related eye conditions (E09.3-, E10.3-, E11.3-, E13.3-)
- E10.43 Type 1 diabetes mellitus with diabetic autonomic (poly)neuropathy
- K31 Other diseases of stomach and duodenum: diabetic gastroparesis (E08.43, E09.43, E10.43, E11.43, E13.43)
- E10.621 Type 1 diabetes mellitus with foot ulcer
- E10.622 Type 1 diabetes mellitus with other skin ulcer
- L89 Pressure ulcer: diabetic ulcers (E08.621, E08.622, E09.621, E09.622, E10.621, E10.622, E11.621, E11.622, E13.621, E13.622)
- E11.311-E11.359 Type 2 diabetes mellitus with unspecified diabetic retinopathy with macular edema to Type 2 diabetes mellitus with proliferative diabetic retinopathy without macular edema 50 codes
- H35 Other retinal disorders: diabetic retinal disorders (E08.311-E08.359, E09.311-E09.359, E10.311-E10.359, E11.311-E11.359, E13.311-E13.359)
- Chapter 7 (H00-H59) Diseases of the eye and adnexa: diabetes mellitus related eye conditions (E09.3-, E10.3-, E11.3-, E13.3-)
- E11.43 Type 2 diabetes mellitus with diabetic autonomic (poly)neuropathy
- K31 Other diseases of stomach and duodenum: diabetic gastroparesis (E08.43, E09.43, E10.43, E11.43, E13.43)
- E11.621 Type 2 diabetes mellitus with foot ulcer
- E11.622 Type 2 diabetes mellitus with other skin ulcer
- L89 Pressure ulcer: diabetic ulcers (E08.621, E08.622, E09.621, E09.622, E10.621, E10.622, E11.621, E11.622, E13.621, E13.622)
- E87.0 Hyperosmolality and hypernatremia: diabetes with hyperosmolarity (E08, E09, E11, E13 with final characters .00 or .01)
- E13.311-E13.359 Other specified diabetes mellitus with unspecified diabetic retinopathy with macular edema to Other specified diabetes mellitus with proliferative diabetic retinopathy without macular edema 50 codes
- H35 Other retinal disorders: diabetic retinal disorders (E08.311-E08.359, E09.311-E09.359, E10.311-E10.359, E11.311-E11.359, E13.311-E13.359)
- Chapter 7 (H00-H59) Diseases of the eye and adnexa: diabetes mellitus related eye conditions (E09.3-, E10.3-, E11.3-, E13.3-)
- E13.43 Other specified diabetes mellitus with diabetic autonomic (poly)neuropathy
- K31 Other diseases of stomach and duodenum: diabetic gastroparesis (E08.43, E09.43, E10.43, E11.43, E13.43)
- E13.621 Other specified diabetes mellitus with foot ulcer
- E13.622 Other specified diabetes mellitus with other skin ulcer
- L89 Pressure ulcer: diabetic ulcers (E08.621, E08.622, E09.621, E09.622, E10.621, E10.622, E11.621, E11.622, E13.621, E13.622)
- E87.0 Hyperosmolality and hypernatremia: diabetes with hyperosmolarity (E08, E09, E11, E13 with final characters .00 or .01)
- E20.1 Pseudohypoparathyroidism
- E34.8 Other specified endocrine disorders: pseudohypoparathyroidism (E20.1)
- E23.0 Hypopituitarism
- N97 Female infertility: hypopituitarism (E23.0)
- Chapter 15 (O00-O9A) Pregnancy, childbirth and the puerperium: postpartum necrosis of pituitary gland (E23.0)
- E23.6 Other disorders of pituitary gland
- E66 Overweight and obesity: adiposogenital dystrophy (E23.6)
- E28.2 Polycystic ovarian syndrome
- N97 Female infertility: Stein-Leventhal syndrome (E28.2)
- QA1 Genetic disorders associated with neoplasms, not elsewhere classified: multiple endocrine neoplasia [MEN] syndromes (E31.2-)
- E36.0- Intraoperative hemorrhage and hematoma of an endocrine system organ or structure complicating a procedure 2 codes
- E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified: intraoperative complications of endocrine system organ or structure (E36.0-, E36.1-, E36.8)
- E36.1- Accidental puncture and laceration of an endocrine system organ or structure during a procedure 2 codes
- E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified: intraoperative complications of endocrine system organ or structure (E36.0-, E36.1-, E36.8)
- E36.8 Other intraoperative complications of endocrine system
- E89 Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified: intraoperative complications of endocrine system organ or structure (E36.0-, E36.1-, E36.8)
- Block T80-T88 Complications of surgical and medical care, not elsewhere classified: intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- T81 Complications of procedures, not elsewhere classified: intraoperative and postprocedural complications of specific body system (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95, K91.-, L76.-, M96.-, N99.-)
- E45 Retarded development following protein-calorie malnutrition
- E64.0 Sequelae of protein-calorie malnutrition: retarded development following protein-calorie malnutrition (E45)
- E53.0 Riboflavin deficiency
- Block L00-L08 Infections of the skin and subcutaneous tissue: Perlèche due to riboflavin deficiency (E53.0)
- D51 Vitamin B12 deficiency anemia: deficiency of other B group vitamins (E53-)
- E60 Dietary zinc deficiency
- D53.8 Other specified nutritional anemias: zinc deficiency NOS (E60)
- E61.0 Copper deficiency
- D53.8 Other specified nutritional anemias: copper deficiency NOS (E61.0)
- E61.5 Molybdenum deficiency
- D53.8 Other specified nutritional anemias: molybdenum deficiency NOS (E61.5)
- E63 Other nutritional deficiencies: sequelae of malnutrition and other nutritional deficiencies (E64.-)
- E70.29 Other disorders of tyrosine metabolism
- M24.1 Other articular cartilage disorders: ochronosis (E70.29)
- E70-E88 Disorders of aromatic amino-acid metabolism to Other and unspecified metabolic disorders 286 codes
- G11 Hereditary ataxia: metabolic disorders (E70-E88)
- G71 Primary disorders of muscles: metabolic disorders (E70-E88)
- N25.0 Renal osteodystrophy: metabolic disorders classifiable to E70-E88
- N25.81 Secondary hyperparathyroidism of renal origin: metabolic disorders classifiable to E70-E88
- Chapter 17 (Q00-QA1) Congenital malformations, deformations and chromosomal abnormalities: inborn errors of metabolism (E70-E88)
- E71.42 Carnitine deficiency due to inborn errors of metabolism
- E71.3 Disorders of fatty-acid metabolism: carnitine deficiency due to inborn error of metabolism (E71.42)
- E72.4 Disorders of ornithine metabolism
- E88.0 Disorders of plasma-protein metabolism, not elsewhere classified: disorder of lipoprotein metabolism (E78.-)
- Block R70-R79 Abnormal findings on examination of blood, without diagnosis: abnormalities of lipids (E78.-)
- G11.3 Cerebellar ataxia with defective DNA repair: other disorders of purine and pyrimidine metabolism (E79.-)
- E83.01 Wilson's disease
- Block K70-K77 Diseases of liver: Wilson's disease (E83.01)
- E83.110 Hereditary hemochromatosis
- K76 Other diseases of liver: pigmentary cirrhosis (of liver) (E83.110)
- E83.111 Hemochromatosis due to repeated red blood cell transfusions
- T80 Complications following infusion, transfusion and therapeutic injection: transfusion (red blood cell) associated hemochromatosis (E83.111)
- Block K70-K77 Diseases of liver: hemochromatosis (E83.11-)
- E83.52 Hypercalcemia
- E83.59 Other disorders of calcium metabolism
- M24.1 Other articular cartilage disorders: metastatic calcification (E83.59)
- E83.3 Disorders of phosphorus metabolism and phosphatases: disorders of pyrophosphate metabolism (E83.82-)
- I70.9 Other and unspecified atherosclerosis: disorders of pyrophosphate metabolism (E83.82-)
- Q28.8 Other specified congenital malformations of circulatory system: disorders of pyrophosphate metabolism (E83.82-)
- Q82.8 Other specified congenital malformations of skin: disorders of pyrophosphate metabolism (E83.82-)
- Block J40-J4B Chronic lower respiratory diseases: cystic fibrosis (E84.-)
- K86 Other diseases of pancreas: fibrocystic disease of pancreas (E84.-)
- E85.4 Organ-limited amyloidosis
- E85.0 Non-neuropathic heredofamilial amyloidosis: Transthyretin-related (ATTR) familial amyloid cardiomyopathy (E85.4)
- E86.0 Dehydration
- E63 Other nutritional deficiencies: dehydration (E86.0)
- R79.1 Abnormal coagulation profile: abnormality of fluid, electrolyte or acid-base balance (E86-E87)
- Block T80-T88 Complications of surgical and medical care, not elsewhere classified: disorders of fluid and electrolyte imbalance (E86-E87)
- E87.70 Fluid overload, unspecified
- I50.9 Heart failure, unspecified: fluid overload unrelated to congestive heart failure (E87.70)
- E87.71 Transfusion associated circulatory overload
- E88.2 Lipomatosis, not elsewhere classified
- Block Q90-Q99 Chromosomal abnormalities, not elsewhere classified: mitochondrial metabolic disorders (E88.4-)
- E89.- Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified 17 codes
- E36 Intraoperative complications of endocrine system: postprocedural endocrine and metabolic complications and disorders, not elsewhere classified (E89.-)
- Block T80-T88 Complications of surgical and medical care, not elsewhere classified: intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- T81 Complications of procedures, not elsewhere classified: intraoperative and postprocedural complications of specific body system (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95, K91.-, L76.-, M96.-, N99.-)
- Z90 Acquired absence of organs, not elsewhere classified: postprocedural absence of endocrine glands (E89.-)
The first view lists notes printed in this chapter (a note on a category or block applies to every code beneath it). The second lists codes of this chapter named by Excludes2 Notes anywhere in the Tabular List, including notes in other chapters.
Questions About Excludes2 Notes
What does an Excludes2 note mean?
An Excludes2 note means “Not included here”: the excluded condition is not part of the condition represented by the code, but a patient may have both conditions at the same time (Section I.A.12.b). The FY 2027 Tabular List has 2,529 of them; 2,493 name other codes, with 2,799 references to 1,779 distinct codes, categories and ranges.
Can both codes be reported when there is an Excludes2 note?
Yes. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate: that is, when the patient has both conditions and both are documented.
Related References
Source: FY 2027 ICD-10-CM Tabular List (CMS and NCHS) and the ICD-10-CM Official Guidelines for Coding and Reporting FY 2027, Section I.A. ICD List is not affiliated with CMS or NCHS.