2025 ICD-10-CM Diagnosis Code E46

Approximate Synonyms

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

Clinical Classification

Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.

They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.

Clinical Information

• Hypoalbuminemia

  a condition in which albumin level in blood (serum albumin) is below the normal range. hypoalbuminemia may be due to decreased hepatic albumin synthesis, increased albumin catabolism, altered albumin distribution, or albumin loss through the urine (albuminuria).

• Child Nutrition Disorders

  disorders caused by nutritional imbalance, either overnutrition or undernutrition, occurring in children ages 2 to 12 years.

• Fetal Nutrition Disorders

  disorders caused by nutritional imbalance, either overnutrition or undernutrition, in the fetus in utero.

• Infant Nutrition Disorders

  disorders caused by nutritional imbalance, either overnutrition or undernutrition, occurring in infants ages 1 month to 24 months.

• Malnutrition

  an imbalanced nutritional status resulting from insufficient intake of nutrients to meet normal physiological requirement.

• Protein-Energy Malnutrition

  the lack of sufficient energy or protein to meet the body's metabolic demands, as a result of either an inadequate dietary intake of protein, intake of poor quality dietary protein, increased demands due to disease, or increased nutrient losses.

• Severe Acute Malnutrition

  acute form of malnutrition which usually affects children, characterized by a very low weight for height (below -3z scores of the median world health organization standards), visible severe wasting, or occurrence of nutritional edema. it can be a direct or indirect cause of fatality in children suffering from diarrhea and pneumonia. do not confuse with starvation, a condition in which the body is not getting enough food, usually for extended periods of time.

• Diabetic Ketoacidosis

  a life-threatening complication of diabetes mellitus, primarily of type 1 diabetes mellitus with severe insulin deficiency and extreme hyperglycemia. it is characterized by ketosis; dehydration; and depressed consciousness leading to coma.

• Hypoproteinemia

  a condition in which total serum protein level is below the normal range. hypoproteinemia can be caused by protein malabsorption in the gastrointestinal tract, edema, or proteinuria.

• Protein-Losing Enteropathies

  pathological conditions in the intestines that are characterized by the gastrointestinal loss of serum proteins, including serum albumin; immunoglobulins; and at times lymphocytes. severe condition can result in hypogammaglobulinemia or lymphopenia. protein-losing enteropathies are associated with a number of diseases including intestinal lymphangiectasis; whipple's disease; and neoplasms of the small intestine.

• Fetus

  the unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. in humans, the unborn young from the end of the eighth week after conception until birth, as distinguished from the earlier embryo, mammalian.

• APTX wt Allele|AOA|AOA1|AXA1|Aprataxin wt Allele|Ataxia 1, Early Onset With Hypoalbuminemia Gene|EAOH|EOAHA|FHA-HIT

  human aptx wild-type allele is located in the vicinity of 9p21.1 and is approximately 139 kb in length. this allele, which encodes aprataxin protein, is involved in dna repair. mutation of the gene is associated with ataxia-ocular apraxia type 1.

• Ataxia-Oculomotor Apraxia Type 1|AOA1|Ataxia, Early-Onset, with Oculomotor Apraxia and Hypoalbuminemia|EAOH

  an autosomal recessive cerebellar ataxia caused by mutation(s) in the aptx gene, encoding aprataxin. it is characterized by peripheral axonal neuropathy, oculomotor apraxia, and hypoalbuminemia.

• Grade 1 Hypoalbuminemia, CTCAE|Grade 1 Hypoalbuminemia

• Grade 2 Hypoalbuminemia, CTCAE|Grade 2 Hypoalbuminemia

  <3-2 g/dl; <30-20 g/l

• Grade 3 Hypoalbuminemia, CTCAE|Grade 3 Hypoalbuminemia

  <2 g/dl; <20 g/l

• Grade 4 Hypoalbuminemia, CTCAE|Grade 4 Hypoalbuminemia

  life-threatening consequences; urgent intervention indicated

• Grade 5 Hypoalbuminemia, CTCAE|Grade 5 Hypoalbuminemia

  death

• Hypoalbuminemia

  concentration of serum albumin below normal limits for the age related normal range.

• Hypoalbuminemia, CTCAE|Hypoalbuminemia|Hypoalbuminemia

  a disorder characterized by laboratory test results that indicate a low concentration of albumin in the blood.

• Hypoproteinemia

  a laboratory test result indicating abnormally low levels of total protein in the serum.

E46 is grouped with Diagnostic Related Groups - MS-DRG Mapping

Diagnosis-Related Groups (DRGs) are used to classify hospital cases for billing and healthcare management. They help standardize how hospitals and other providers are reimbursed for inpatient care. Patients are grouped based on their principal diagnosis into broader categories called Major Diagnostic Categories (MDCs).

Once assigned to a DRG, the hospital receives a set payment for the patient’s care, regardless of the actual services provided. This fixed rate is intended to cover the typical cost of treating patients within that group. The payment amount depends on the DRG's relative weight, which reflects the expected complexity and cost of care based on the severity of the patient’s condition.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V42.0 applicable from 10/01/2024 through 09/30/2025.

Convert E46 to ICD-9-CM

Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.

Patient Education

Malnutrition

Food provides the energy and nutrients you need to be healthy. If you don't get enough nutrients -- including proteins, carbohydrates, fats, vitamins, and minerals - you may suffer from malnutrition.

Causes of malnutrition include:

• Lack of specific nutrients in your diet. Even the lack of one vitamin can lead to malnutrition.
• An unbalanced diet
• Certain medical problems, such as malabsorption syndromes and cancers

Symptoms may include fatigue, dizziness, and weight loss. Or, you may have no symptoms. To diagnose the cause of the problem, your doctor may do blood tests and a nutritional assessment. Treatment may include replacing the missing nutrients and treating the underlying cause.

[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.