2026 ICD-10-CM Diagnosis Code T80Complications following infusion, transfusion and therapeutic injection

ICD-10-CM Codes›S00–T88›T80-T88›T80

ICD-10-CM T80
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T80 is a non-billable ICD-10-CM category code for complications following infusion, transfusion and therapeutic injection, so it cannot be submitted on claims. Use a more specific code from this category instead, such as T80.0XXA, T80.0XXD, T80.0XXS, and T80.1XXA.

Code Identity

ICD-10-CM Code
T80
Billable Status
No — Non-Billable Category
Code Describes
Complications following infusion, transfusion and therapeutic injection
Chapter
T80-T88
Complications of surgical and medical care, not elsewhere classified

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT80-T88Complications of surgical and medical care, not elsewhere classified
CategoryT80Complications following infusion, transfusion and therapeutic injection
This CodeT80Complications following infusion, transfusion and therapeutic injection

Specific Coding for Comp following infusion, transfusion and theraputc injectionOverview

Non-specific codes like T80 require more characters. Use one of these billable codes instead:

  • T80.0 for Air embolism following infusion, transfusion and therapeutic injection

  • T80.1 for Vascular complications following infusion, transfusion and therapeutic injection

  • T80.2 for Infections following infusion, transfusion and therapeutic injection

  • T80.21 for Infection due to central venous catheter

  • T80.22 for Acute infection following transfusion, infusion, or injection of blood and blood products

  • T80.29 for Infection following other infusion, transfusion and therapeutic injection

  • T80.3 for ABO incompatibility reaction due to transfusion of blood or blood products

  • T80.30 for ABO incompatibility reaction due to transfusion of blood or blood products, unspecified

  • T80.31 for ABO incompatibility with hemolytic transfusion reaction

  • T80.39 for Other ABO incompatibility reaction due to transfusion of blood or blood products

  • T80.4 for Rh incompatibility reaction due to transfusion of blood or blood products

  • T80.40 for Rh incompatibility reaction due to transfusion of blood or blood products, unspecified

  • T80.41 for Rh incompatibility with hemolytic transfusion reaction

  • T80.49 for Other Rh incompatibility reaction due to transfusion of blood or blood products

  • T80.5 for Anaphylactic reaction due to serum

  • T80.51 for Anaphylactic reaction due to administration of blood and blood products

  • T80.52 for Anaphylactic reaction due to vaccination

  • T80.59 for Anaphylactic reaction due to other serum

  • T80.6 for Other serum reactions

  • T80.61 for Other serum reaction due to administration of blood and blood products

  • T80.62 for Other serum reaction due to vaccination

  • T80.69 for Other serum reaction due to other serum

  • T80.8 for Other complications following infusion, transfusion and therapeutic injection

  • T80.81 for Extravasation of vesicant agent

  • T80.82 for Complication of immune effector cellular therapy

  • T80.89 for Other complications following infusion, transfusion and therapeutic injection

  • T80.9 for Unspecified complication following infusion, transfusion and therapeutic injection

  • T80.90 for Unspecified complication following infusion and therapeutic injection

  • T80.91 for Hemolytic transfusion reaction, unspecified incompatibility

  • T80.92 for Unspecified transfusion reaction

  • T80.A for Non-ABO incompatibility reaction due to transfusion of blood or blood products

  • T80.A0 for Non-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified

  • T80.A1 for Non-ABO incompatibility with hemolytic transfusion reaction

  • T80.A9 for Other non-ABO incompatibility reaction due to transfusion of blood or blood products

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Complications following infusion, transfusion and therapeutic injection (T80). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Includes

  • complications following perfusion

Type 2 Excludes

  • bone marrow transplant rejection T86.01
  • febrile nonhemolytic transfusion reaction R50.84
  • fluid overload due to transfusion E87.71
  • posttransfusion purpura D69.51
  • transfusion associated circulatory overload TACO E87.71
  • transfusion red blood cell associated hemochromatosis E83.111
  • transfusion related acute lung injury TRALI J95.84

7th Character Note

  • The appropriate 7th character is to be added to each code from category T80

7th Character

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T80Overview

Is T80 a billable code?

No. This is a category header that groups the codes for complications following infusion, transfusion and therapeutic injection, and headers cannot be submitted on claims. Claims for complications following infusion, transfusion and therapeutic injection need a more specific code from this category, such as T80.0XXA, T80.0XXD, and T80.0XXS.