2027 ICD-10-CM Diagnosis Code E53Deficiency of other B group vitamins

ICD-10-CM Codes›E00–E89›E50-E64›E53

ICD-10-CM E53
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E53 is a non-billable ICD-10-CM category code for deficiency of other B group vitamins, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E53.0, E53.1, E53.8, and E53.9.

Code Identity

ICD-10-CM Code
E53
Billable Status
No — Non-Billable Category
Code Describes
Deficiency of other B group vitamins
Short Description
Deficiency of other B group vitamins
Same as the full description in the CMS dataset.
Chapter
E50-E64
Other nutritional deficiencies

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE50-E64Other nutritional deficiencies
CategoryE53Deficiency of other B group vitamins
This CodeE53Deficiency of other B group vitamins

Specific Coding for Deficiency of other B group vitaminsOverview

Non-specific codes like E53 require more characters. Use one of these billable codes instead:

  • Use E53.0 for Riboflavin deficiency

  • Use E53.1 for Pyridoxine deficiency

  • Use E53.8 for Deficiency of other specified B group vitamins

  • Use E53.9 for Vitamin B deficiency, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E53: its own notes plus those printed at block E50-E64 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E53 itself
  • sequelae of vitamin B deficiency (E64.8)
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block E50-E64 Other nutritional deficiencies applies to 50 codes

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E53, its category, or a range that includes it.

Applicable To 1

These notes mention E53.

  • P00.4 Newborn affected by maternal nutritional disorders
    Newborn affected by maternal disorders classifiable to E40-E64 names E40-E64, which includes this code

Excludes1 2

These codes carry an Excludes1 note naming E53: they are not reported together with it, unless the two conditions are unrelated.

  • T45.2X6 Underdosing of vitamins
    vitamin deficiencies (E50-E56) names E50-E56, which includes this code
  • Z72.4 Inappropriate diet and eating habits
    malnutrition and other nutritional deficiencies (E40-E64) names E40-E64, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming E53: its condition is not part of those codes, and both may be reported when the patient has both.

  • D51 Vitamin B12 deficiency anemia
    deficiency of other B group vitamins (E53-)

Code First 3

These codes say to code first a condition named in the note, and E53 is one of the conditions named.

  • F06.7 Mild neurocognitive disorder due to known physiological condition
    vitamin B deficiency (E53.-)
  • G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
    cerebral degeneration (due to) vitamin B deficiency, except thiamine (E52-E53.-) names E52-E53, which includes this code
  • G63 Polyneuropathy in diseases classified elsewhere
    nutritional deficiency (E40-E64) names E40-E64, which includes this code

Notes 1

These notes mention E53.

  • E64 Sequelae of malnutrition and other nutritional deficiencies
    This category is to be used to indicate conditions in categories E43, E44, E46, E50-E63 as the cause of sequelae, which are themselves classified elsewhere. The 'sequelae' include conditions specified as such; they also include the late effects of diseases classifiable to the above categories if the disease itself is no longer present names E50-E63, which includes this code

Patient EducationClinical

B Vitamins

The B vitamins are:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E53Overview

What is the ICD-10 code for deficiency of other B group vitamins?

E53 is the ICD-10-CM category for deficiency of other B group vitamins, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E53 (Deficiency of other B group vitamins) a billable code?

No. This is a category header that groups the codes for deficiency of other B group vitamins, and headers cannot be submitted on claims. Claims for deficiency of other B group vitamins need a more specific code from this category, such as E53.0, E53.1, and E53.8.

Can E53 be reported with E64.8?

Not as a rule. The Excludes1 note on E53 lists "sequelae of vitamin B deficiency (E64.8)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).