ICD-10-CM Excludes2 Notes · Chapter 3 · FY 2027 D50-D89
Excludes2 Notes in Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism ICD-10-CM
An Excludes2 note means "NOT INCLUDED HERE": the excluded condition is not part of this code, but a patient may have both, so both codes may be reported. In Chapter 3 (D50-D89), notes printed in the chapter name other codes 54 times, and Excludes2 Notes anywhere in the Tabular List name the chapter’s codes 40 times, covering 24 distinct codes, categories and ranges. Switch views to read the list either way.
✓ From the official FY 2027 ICD-10-CM Tabular ListDefinitions follow the Official Guidelines, Section I.A
54
References in Its Notes
40
References to Its Codes
24
Chapter Codes Named
D50-D89
Chapter 3
Chapter 3
Excludes2 Notes by the code that carries the note
23 of 23 shown
- Chapter note Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism applies to 324 codes
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- deficiency of other B group vitamins (E53-)
- D53.8 Other specified nutritional anemias
- neutropenia (D70.-)
- pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)
- D61.810 Antineoplastic chemotherapy induced pancytopenia
- aplastic anemia due to antineoplastic chemotherapy (D61.1)
- D61.811 Other drug-induced pancytopenia
- aplastic anemia due to drugs (D61.1)
- D63.0 Anemia in neoplastic disease
- anemia due to antineoplastic chemotherapy (D64.81)
- D64.81 Anemia due to antineoplastic chemotherapy
- D65 Disseminated intravascular coagulation [defibrination syndrome]
- D68.312 Antiphospholipid antibody with hemorrhagic disorder
- D68.61 Antiphospholipid syndrome
- D68.62 Lupus anticoagulant syndrome
- von Willebrand disease (D68.0-)
- neutropenia (D70)
- neutropenia (D70)
- essential thrombocythemia (D47.3)
- human immunodeficiency virus [HIV] disease (B20)
- transplant failure and rejection (T86.-)
- D50.1 Sideropenic dysphagia
- K22.8 Other specified diseases of esophagus: Paterson-Kelly syndrome (D50.1)
- Block E40-E46 Malnutrition: nutritional anemias (D50-D53)
- Block E50-E64 Other nutritional deficiencies: nutritional anemias (D50-D53)
- E53.8 Deficiency of other specified B group vitamins: vitamin B12 deficiency anemia (D51.-)
- Block N17-N19 Acute kidney failure and chronic kidney disease: hemolytic-uremic syndrome (D59.3-)
- D59.6 Hemoglobinuria due to hemolysis from other external causes
- D59.1 Other autoimmune hemolytic anemias: paroxysmal cold hemoglobinuria (D59.6)
- D61.1 Drug-induced aplastic anemia
- D46 Myelodysplastic syndromes: drug-induced aplastic anemia (D61.1)
- D61.810 Antineoplastic chemotherapy induced pancytopenia: aplastic anemia due to antineoplastic chemotherapy (D61.1)
- D61.811 Other drug-induced pancytopenia: aplastic anemia due to drugs (D61.1)
- D64.81 Anemia due to antineoplastic chemotherapy: aplastic anemia due to antineoplastic chemotherapy (D61.1)
- D63.0 Anemia in neoplastic disease
- D64.81 Anemia due to antineoplastic chemotherapy: anemia in neoplastic disease (D63.0)
- D64.81 Anemia due to antineoplastic chemotherapy
- D63.0 Anemia in neoplastic disease: anemia due to antineoplastic chemotherapy (D64.81)
- D65-D68 Disseminated intravascular coagulation [defibrination syndrome] to Other coagulation defects 28 codes
- Block R70-R79 Abnormal findings on examination of blood, without diagnosis: coagulation hemorrhagic disorders (D65-D68)
- D69.1 Qualitative platelet defects: von Willebrand disease (D68.0-)
- D68.312 Antiphospholipid antibody with hemorrhagic disorder
- D68.61 Antiphospholipid syndrome
- D68.312 Antiphospholipid antibody with hemorrhagic disorder: antiphospholipid antibody syndrome (D68.61)
- D68.312 Antiphospholipid antibody with hemorrhagic disorder: antiphospholipid antibody with hypercoagulable state (D68.61)
- D68.62 Lupus anticoagulant syndrome: anticardiolipin syndrome (D68.61)
- D68.62 Lupus anticoagulant syndrome: antiphospholipid syndrome (D68.61)
- D68.62 Lupus anticoagulant syndrome
- D68.312 Antiphospholipid antibody with hemorrhagic disorder: lupus anticoagulant (LAC) with hypercoagulable state (D68.62)
- D68.312 Antiphospholipid antibody with hemorrhagic disorder: systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.62)
- D68.61 Antiphospholipid syndrome: lupus anticoagulant syndrome (D68.62)
- D69.41 Evans syndrome
- D59.1 Other autoimmune hemolytic anemias: Evans syndrome (D69.41)
- D69.51 Posttransfusion purpura
- T80 Complications following infusion, transfusion and therapeutic injection: posttransfusion purpura (D69.51)
- Block R70-R79 Abnormal findings on examination of blood, without diagnosis: abnormalities of platelets and thrombocytes (D69.-)
- Block R70-R79 Abnormal findings on examination of blood, without diagnosis: abnormalities of white blood cells classified elsewhere (D70-D72)
- Block L20-L30 Dermatitis and eczema: chronic (childhood) granulomatous disease (D71-)
- D75.1 Secondary polycythemia
- T70.2 Other and unspecified effects of high altitude: polycythemia due to high altitude (D75.1)
- D75.838 Other thrombocytosis
- D75.839 Thrombocytosis, unspecified
- Block T80-T88 Complications of surgical and medical care, not elsewhere classified: intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- T81 Complications of procedures, not elsewhere classified: intraoperative and postprocedural complications of specific body system (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95, K91.-, L76.-, M96.-, N99.-)
- D84.821 Immunodeficiency due to drugs
- Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances: immunodeficiency due to drugs (D84.821)
- D89.2 Hypergammaglobulinemia, unspecified
- D75 Other and unspecified diseases of blood and blood-forming organs: hypergammaglobulinemia NOS (D89.2)
The first view lists notes printed in this chapter (a note on a category or block applies to every code beneath it). The second lists codes of this chapter named by Excludes2 Notes anywhere in the Tabular List, including notes in other chapters.
Questions About Excludes2 Notes
What does an Excludes2 note mean?
An Excludes2 note means “Not included here”: the excluded condition is not part of the condition represented by the code, but a patient may have both conditions at the same time (Section I.A.12.b). The FY 2027 Tabular List has 2,529 of them; 2,493 name other codes, with 2,799 references to 1,779 distinct codes, categories and ranges.
Can both codes be reported when there is an Excludes2 note?
Yes. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate: that is, when the patient has both conditions and both are documented.
Related References
Source: FY 2027 ICD-10-CM Tabular List (CMS and NCHS) and the ICD-10-CM Official Guidelines for Coding and Reporting FY 2027, Section I.A. ICD List is not affiliated with CMS or NCHS.
