2027 ICD-10-CM Diagnosis Code E08Diabetes mellitus due to underlying condition

ICD-10-CM Codes›E00–E89›E08-E13›E08

ICD-10-CM E08
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E08 is a non-billable ICD-10-CM category code for diabetes mellitus due to underlying condition, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E08.00, E08.01, E08.10, and E08.11.

Code Identity

ICD-10-CM Code
E08
Billable Status
No — Non-Billable Category
Code Describes
Diabetes mellitus due to underlying condition
Short Description
Diabetes mellitus due to underlying condition
Same as the full description in the CMS dataset.
Chapter
E08-E13
Diabetes mellitus

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE08-E13Diabetes mellitus
CategoryE08Diabetes mellitus due to underlying condition
This CodeE08Diabetes mellitus due to underlying condition

Specific Coding for Diabetes mellitus due to underlying conditionOverview

Non-specific codes like E08 require more characters. Use one of these billable codes instead:

  • E08.0 for Diabetes mellitus due to underlying condition with hyperosmolarity

  • Use E08.00 for Diabetes mellitus due to underlying condition with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC)

  • Use E08.01 for Diabetes mellitus due to underlying condition with hyperosmolarity with coma

  • E08.1 for Diabetes mellitus due to underlying condition with ketoacidosis

  • Use E08.10 for Diabetes mellitus due to underlying condition with ketoacidosis without coma

  • Use E08.11 for Diabetes mellitus due to underlying condition with ketoacidosis with coma

  • E08.2 for Diabetes mellitus due to underlying condition with kidney complications

  • Use E08.21 for Diabetes mellitus due to underlying condition with diabetic nephropathy

  • Use E08.22 for Diabetes mellitus due to underlying condition with diabetic chronic kidney disease

  • Use E08.29 for Diabetes mellitus due to underlying condition with other diabetic kidney complication

  • E08.3 for Diabetes mellitus due to underlying condition with ophthalmic complications

  • E08.31 for Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy

  • E08.32 for Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy

  • E08.33 for Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy

  • E08.34 for Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy

  • E08.35 for Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy

  • Use E08.36 for Diabetes mellitus due to underlying condition with diabetic cataract

  • E08.37 for Diabetes mellitus due to underlying condition with diabetic macular edema, resolved following treatment

  • Use E08.39 for Diabetes mellitus due to underlying condition with other diabetic ophthalmic complication

  • E08.4 for Diabetes mellitus due to underlying condition with neurological complications

  • Use E08.40 for Diabetes mellitus due to underlying condition with diabetic neuropathy, unspecified

  • Use E08.41 for Diabetes mellitus due to underlying condition with diabetic mononeuropathy

  • Use E08.42 for Diabetes mellitus due to underlying condition with diabetic polyneuropathy

  • Use E08.43 for Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy

  • Use E08.44 for Diabetes mellitus due to underlying condition with diabetic amyotrophy

  • Use E08.49 for Diabetes mellitus due to underlying condition with other diabetic neurological complication

  • E08.5 for Diabetes mellitus due to underlying condition with circulatory complications

  • Use E08.51 for Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy without gangrene

  • Use E08.52 for Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene

  • Use E08.59 for Diabetes mellitus due to underlying condition with other circulatory complications

  • E08.6 for Diabetes mellitus due to underlying condition with other specified complications

  • E08.61 for Diabetes mellitus due to underlying condition with diabetic arthropathy

  • E08.62 for Diabetes mellitus due to underlying condition with skin complications

  • E08.63 for Diabetes mellitus due to underlying condition with oral complications

  • E08.64 for Diabetes mellitus due to underlying condition with hypoglycemia

  • Use E08.65 for Diabetes mellitus due to underlying condition with hyperglycemia

  • Use E08.69 for Diabetes mellitus due to underlying condition with other specified complication

  • Use E08.8 for Diabetes mellitus due to underlying condition with unspecified complications

  • Use E08.9 for Diabetes mellitus due to underlying condition without complications

Coding GuidelinesGuidance

The diabetes mellitus codes are combination codes that include the type of diabetes mellitus, the body system affected, and the complications affecting that body system. As many codes within a particular category as are necessary to describe all of the complications of the disease may be used. They should be sequenced based on the reason for a particular encounter. Assign as many codes from categories E08 - E13 as needed to identify all of the associated conditions that the patient has.

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E08: its own notes plus those printed at Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E08 itself
  • drug or chemical induced diabetes mellitus (E09.-)
  • gestational diabetes (O24.4-)
  • neonatal diabetes mellitus (P70.2)
  • postpancreatectomy diabetes mellitus (E13.-)
  • postprocedural diabetes mellitus (E13.-)
  • secondary diabetes mellitus NEC (E13.-)
  • type 1 diabetes mellitus (E10.-)
  • type 2 diabetes mellitus (E11.-)
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Code First

The underlying condition named in the note is sequenced before this code.

  • the underlying condition, such as:
  • congenital rubella (P35.0)
  • Cushing's syndrome (E24.-)
  • cystic fibrosis (E84.-)
  • malignant neoplasm (C00-C96)
  • malnutrition (E40-E46)
  • pancreatitis and other diseases of the pancreas (K85-K86.-)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

  • code to identify control using:
  • injectable non-insulin antidiabetic drugs (Z79.85)
  • insulin (Z79.4)
  • oral antidiabetic drugs (Z79.84)
  • oral hypoglycemic drugs (Z79.84)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E08, its category, or a range that includes it.

Excludes1 4

These codes carry an Excludes1 note naming E08: they are not reported together with it, unless the two conditions are unrelated.

  • E09 Drug or chemical induced diabetes mellitus
    diabetes mellitus due to underlying condition (E08.-)
  • E10 Type 1 diabetes mellitus
    diabetes mellitus due to underlying condition (E08.-)
  • E11 Type 2 diabetes mellitus
    diabetes mellitus due to underlying condition (E08.-)
  • E13 Other specified diabetes mellitus
    diabetes mellitus due to underlying condition (E08.-)

Excludes2 2

These codes carry an Excludes2 note naming E08: its condition is not part of those codes, and both may be reported when the patient has both.

  • E87.0 Hyperosmolality and hypernatremia
    diabetes with hyperosmolarity (E08, E09, E11, E13 with final characters .00 or .01)
  • R11.15 Cyclical vomiting syndrome unrelated to migraine
    diabetes mellitus due to underlying condition (E08.-)

Use Additional Code 2

These codes say to use an additional code from the note, and E08 is one of the codes named.

  • O24.8 Other pre-existing diabetes mellitus in pregnancy, childbirth, and the puerperium
    from categories E08, E09 and E13 to further identify any manifestation
  • O24.9 Unspecified diabetes mellitus in pregnancy, childbirth and the puerperium
    from categories E08, E09 and E13 to further identify any manifestation

Patient EducationClinical

Diabetes

Diabetes, also known as diabetes mellitus, is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose is your body's main source of energy. Your body can make glucose, but it also comes from the food you eat. Insulin is a hormone made by your pancreas.

The full article covers:

  • What is diabetes?
  • What are the types of diabetes?
  • What causes diabetes?
  • Who is more likely to develop diabetes?
  • What are the symptoms of diabetes?
  • How is diabetes diagnosed?
  • What are the treatments for diabetes?
  • Can diabetes be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E08Overview

What is the ICD-10 code for diabetes mellitus due to underlying condition?

E08 is the ICD-10-CM category for diabetes mellitus due to underlying condition, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E08 (Diabetes mellitus due to underlying condition) a billable code?

No. This is a category header that groups the codes for diabetes mellitus due to underlying condition, and headers cannot be submitted on claims. Claims for diabetes mellitus due to underlying condition need a more specific code from this category, such as E08.00, E08.01, and E08.10.

Can E08 be reported with a code from E09?

Not as a rule. The Excludes1 note on E08 lists "drug or chemical induced diabetes mellitus (E09.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does E08 need an additional code?

When the condition applies, yes. The Use Additional Code note reads: code to identify control using: injectable non-insulin antidiabetic drugs (Z79.85); insulin (Z79.4); oral antidiabetic drugs (Z79.84); oral hypoglycemic drugs (Z79.84). The additional code is reported after E08.