2026 ICD-10-CM Diagnosis Code E88.810Metabolic syndrome

ICD-10-CM Codes›E00–E89›E70-E88›E88

ICD-10-CM E88.810
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E88.810 is a billable ICD-10-CM diagnosis code for metabolic syndrome. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as metabolic syndrome X. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E88.810
Billable Status
Yes — Valid for Submission
Code Describes
Metabolic syndrome
Short Description
Metabolic syndrome
Same as the full description in the CMS dataset.
Parent Code
E88.81
Metabolic syndrome and other insulin resistance

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE88Other and unspecified metabolic disorders
This CodeE88.810Metabolic syndrome

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Metabolic syndrome X

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Dysmetabolic syndrome

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Dysmetabolic syndrome X
    • Metabolic syndrome
    • Syndrome
      • dysmetabolic X
    • Syndrome
      • metabolic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Metabolic Syndrome

    a cluster of symptoms that are risk factors for cardiovascular diseases and type 2 diabetes mellitus. the major components of metabolic syndrome include abdominal obesity; atherogenic dyslipidemia; hypertension; hyperglycemia; insulin resistance; a proinflammatory state; and a prothrombotic (thrombosis) state.

Patient EducationClinical

Metabolic Syndrome

Metabolic syndrome is the name for a group of risk factors for heart disease, diabetes, and other health problems. You can have just one risk factor, but people often have several of them together. When you have at least three of them, it is called metabolic syndrome. These risk factors include:

The full article covers:

  • What is metabolic syndrome?
  • What causes metabolic syndrome?
  • Who is at risk for metabolic syndrome?
  • What are the symptoms of metabolic syndrome?
  • How is metabolic syndrome diagnosed?
  • What are the treatments for metabolic syndrome?
  • Can metabolic syndrome be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement E88.810 replaces the following previously assigned code(s):

  • E88.81 - Metabolic syndrome
  • E88.81 - Metabolic syndrome and other insulin resistance
FY 2024AddedAdded to the ICD-10-CM code setEffective October 1, 2023.
FY 2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E88.810Overview

Is E88.810 (Metabolic syndrome and other insulin resistance) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report metabolic syndrome on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.