2027 ICD-10-CM Diagnosis Code E88.11Partial lipodystrophy
ICD-10-CM Codes›E00–E89›E70-E88›E88
- Billable — Valid for Submission
- Chronic Condition
E88.11 is a billable ICD-10-CM diagnosis code for partial lipodystrophy. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 642. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Acquired partial lipodystrophy
- AKT2-related familial partial lipodystrophy
- Autosomal semi-dominant severe lipodystrophic laminopathy
- CIDEC-related familial partial lipodystrophy
- Familial partial lipodystrophy
- Familial partial lipodystrophy Dunnigan type
- Familial partial lipodystrophy Kobberling type
- Insulin resistance
- LIPE-related familial partial lipodystrophy
- Lipodystrophy, demyelinating peripheral sensory motor neuropathy syndrome
- Lipodystrophy, partial, with Rieger anomaly, short stature, and insulinopenic diabetes mellitus
- Malabsorption of glucose
- Partial face-sparing lipodystrophy
- Perilipin 1 related familial partial lipodystrophy
- PPARG-related familial partial lipodystrophy
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E88.11: its own notes plus those printed at E88.1, E88, block E70-E88, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Acquired partial lipodystrophy (APL)
- Barraquer-Simons lipodystrophy
- Familial partial lipodystrophy (FPLD)
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- histiocytosis X (chronic) (C96.6)
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- Ehlers-Danlos syndromes (Q79.6-)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- codes for associated conditions
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disease, diseased See Also: Syndrome;
Lipodystrophia progressiva E88.11
progressive E88.11
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Partial Lipodystrophy
loss and redistribution of subcutaneous and/or visceral adipose tissue from specific regions of the body.Lipodystrophy
a collection of heterogenous conditions resulting from defective lipid metabolism and characterized by adipose tissue atrophy. often there is redistribution of body fat resulting in peripheral fat wasting and central adiposity. they include generalized, localized, congenital, and acquired lipodystrophy.
Patient EducationClinical
Metabolic Disorders
Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Code History & ChangesHistory
Replacement E88.11 replaces the following previously assigned code(s):
- E88.1 - Lipodystrophy, not elsewhere classified
Questions About E88.11Overview
What is the ICD-10 code for partial lipodystrophy?
The ICD-10-CM code for partial lipodystrophy is E88.11 (sometimes written as E8811). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E88.11 (Lipodystrophy, not elsewhere classified) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report partial lipodystrophy on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E88.11 group to?
When partial lipodystrophy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 642 (inborn and Other Disorders of Metabolism), which carries a relative weight of 1.3226. Higher weights mean higher Medicare reimbursement.
Can E88.11 be reported with K90.81?
Not as a rule. The Excludes1 note at E88.1, which applies to E88.11, lists "Whipple's disease (K90.81)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
Does E88.11 need an additional code?
When the condition applies, yes. The Use Additional Code note at E88, which applies to E88.11, reads: codes for associated conditions. The additional code is reported after E88.11.
