2026 ICD-10-CM Diagnosis Code D68.2Hereditary deficiency of other clotting factors

ICD-10-CM Codes›D50–D89›D65-D69›D68

ICD-10-CM D68.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D68.2 is a billable ICD-10-CM diagnosis code for hereditary deficiency of other clotting factors. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 813. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 50 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coagulation and hemorrhagic disorders.

For Medicare Advantage risk adjustment, D68.2 maps to CMS-HCC Category 112 (Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions) under the V28 model, adding a risk factor of about 0.450 for a community, non-dual, aged beneficiary in payment year 2026.

Code Identity

ICD-10-CM Code
D68.2
Billable Status
Yes — Valid for Submission
Code Describes
Hereditary deficiency of other clotting factors
Short Description
Hereditary deficiency of other clotting factors
Same as the full description in the CMS dataset.
Parent Code
D68
Other coagulation defects

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD65-D69Coagulation defects, purpura and other hemorrhagic conditions
CategoryD68Other coagulation defects
This CodeD68.2Hereditary deficiency of other clotting factors

Medicare Risk Adjustment (HCC)Billing

D68.2 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2026.

CMS-HCC V28 Category (Payment Model)
HCC 112— Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions
Payment HCC · PY 2026 one of 21 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.450
community, non-dual, aged · ranges 0.450–0.708 across segments
Hierarchy
Superseded by HCC 111
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
HCC 48
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 48 · ESRD (V21): HCC 48 · ESRD (V24): HCC 48
ESRD V21 weights: 0.059 dialysis, 0.173–0.234 functioning graft · ESRD V24 weights: 0.063 dialysis, 0.192–0.358 functioning graft
Part D (RxHCC)
Not mapped
D68.2 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired coagulation factor inhibitor disorder
  • Alpha chain defect dysfibrinogenemia
  • Autosomal dominant deficiency of plasminogen
  • Beta chain defect dysfibrinogenemia
  • Combined deficiency of factor V and factor VIII
  • Congenital afibrinogenemia
  • Congenital fibrinogen abnormality
  • Congenital plasminogen activator inhibitor deficiency type 1
  • Contact factor deficiency
  • Drug-induced coagulation inhibitor disorder
  • Dysfibrinogenemia
  • Dysplasminogenemia
  • Factor I deficiency
  • Factor I deficiency disease
  • Factor II deficiency
  • Factor V deficiency
  • Factor V short isoforms related bleeding disorder
  • Factor VII deficiency
  • Factor X deficiency
  • Factor XII deficiency disease
  • Factor XIII deficiency disease
  • Factor XIII inhibitor disorder
  • Fibrinogen abnormality
  • Fibrinogen deficiency
  • Fibrinogen in blood above reference range
  • Fibrinolytic bleeding syndrome
  • Gamma chain defect dysfibrinogenemia
  • Hemorrhagic disease of the newborn due to factor II deficiency
  • Heparin cofactor II deficiency
  • Hereditary combined coagulation factor deficiency
  • Hereditary combined deficiency of vitamin K-dependent clotting factors
  • Hereditary congenital prekallikrein deficiency
  • Hereditary dysfibrinogenemia
  • Hereditary dysplasminogenemia
  • Hereditary factor I deficiency disease
  • Hereditary factor II deficiency disease
  • Hereditary factor V deficiency disease
  • Hereditary factor VII deficiency disease
  • Hereditary factor X deficiency disease
  • Hereditary factor XII deficiency disease
  • Hereditary factor XIII A subunit and B subunit deficiency
  • Hereditary factor XIII A subunit deficiency
  • Hereditary factor XIII B subunit deficiency
  • Hereditary factor XIII deficiency disease
  • Hereditary hypoplasminogenemia
  • Hereditary thrombophilic dysfibrinogenemia
  • High molecular weight kininogen deficiency
  • Hyperfibrinogenemia
  • Hypodysfibrinogenemia
  • Hypoplasminogenemia
  • Immunodeficiency with factor I anomaly
  • Neonatal coagulation disorder
  • Passovoy factor deficiency
  • Platelet factor V deficiency
  • Platelet procoagulant activity deficiency
  • Prekallikrein deficiency
  • Prothrombin complex deficiency

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • AC globulin deficiency
  • Congenital afibrinogenemia
  • Deficiency of factor I [fibrinogen]
  • Deficiency of factor II [prothrombin]
  • Deficiency of factor V [labile]
  • Deficiency of factor VII [stable]
  • Deficiency of factor X [Stuart-Prower]
  • Deficiency of factor XII [Hageman]
  • Deficiency of factor XIII [fibrin stabilizing]
  • Dysfibrinogenemia (congenital)
  • Hypoproconvertinemia
  • Owren's disease
  • Proaccelerin deficiency

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD006
Coagulation and hemorrhagic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Factor VII Deficiency

    an autosomal recessive characteristic or a coagulation disorder acquired in association with vitamin k deficiency. factor vii is a vitamin k dependent glycoprotein essential to the extrinsic pathway of coagulation.

  • Factor V Deficiency

    a deficiency of blood coagulation factor v (known as proaccelerin or accelerator globulin or labile factor) leading to a rare hemorrhagic tendency known as owren's disease or parahemophilia. it varies greatly in severity. factor v deficiency is an autosomal recessive trait. (dorland, 27th ed)

  • Factor X Deficiency

    blood coagulation disorder usually inherited as an autosomal recessive trait, though it can be acquired. it is characterized by defective activity in both the intrinsic and extrinsic pathways, impaired thromboplastin time, and impaired prothrombin consumption.

  • Acquired Factor II Deficiency|Acquired hypoprothrombinemia

    an acquired coagulation disorder characterized by the partial or complete absence of prothrombin (factor ii) activity in the blood.

  • Dysfibrinogenemia

    a coagulation disorder caused by abnormalities in fibrin that result in defective clot formation. this disorder may be inherited or acquired.

  • High Molecular Weight Kininogen Deficiency

    a rare autosomal recessive inherited disorder characterized by prolonged partial thromboplastin time and absence of bleeding diathesis.

  • Acquired Factor VII Deficiency

    an acquired coagulation disorder characterized by the partial or complete absence of factor vii activity in the blood.

  • Factor VII Deficiency

    a coagulation disorder characterized by the partial or complete absence of factor vii activity in the blood.

  • Hereditary Factor VII Deficiency

    a rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of factor vii, resulting in bleeding.

  • Acquired Factor V Deficiency

    an acquired coagulation disorder characterized by the partial or complete absence of factor v activity in the blood.

  • Factor V Deficiency

    a coagulation disorder characterized by the partial or complete absence of factor v activity in the blood.

  • Hereditary Factor V Deficiency|Owren Disease

    a very rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of factor v, resulting in bleeding.

  • Prekallikrein Deficiency

    a condition characterized by the congenital or acquired deficiency of prekallikrein. this deficiency is usually not associated with bleeding. the congenital deficiency is very rare. acquired deficiency may occur in diffuse intravascular coagulation, infections, and sickle cell disease.

  • Acquired Factor II Deficiency

    an acquired coagulation disorder characterized by the partial or complete absence of prothrombin (factor ii) activity in the blood.

  • Factor II Deficiency

    a coagulation disorder characterized by the partial or complete absence of prothrombin (factor ii) activity in the blood.

  • Hereditary Factor II Deficiency|Hereditary Hypoprothrombinemia|Hereditary Prothrombin Deficiency

    a very rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of prothrombin, resulting in bleeding.

  • Acquired Factor X Deficiency

    an acquired coagulation disorder characterized by the partial or complete absence of factor x activity in the blood.

  • Factor X Deficiency

    a coagulation disorder characterized by the partial or complete absence of factor x activity in the blood.

  • Hereditary Factor X Deficiency|Stuart-Prower Factor Deficiency

    a rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of factor x, resulting in bleeding.

Patient EducationClinical

Bleeding Disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D68.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
286.3 Cong def clot factor NEC
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D68.2Overview

What is the ICD-10 code for hereditary deficiency of other clotting factors?

The ICD-10-CM code for hereditary deficiency of other clotting factors is D68.2 (sometimes written as D682). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is D68.2 (Other coagulation defects) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hereditary deficiency of other clotting factors on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D68.2 group to?

When hereditary deficiency of other clotting factors is the principal diagnosis on an inpatient stay, it groups to MS-DRG 813 (coagulation Disorders), which carries a relative weight of 1.5253. Higher weights mean higher Medicare reimbursement.

Is D68.2 a CC or MCC?

CMS lists D68.2 as a CC (complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 50 closely related codes in its exclusion list.

What is the ICD-9 equivalent of D68.2?

Under the General Equivalence Mappings, hereditary deficiency of other clotting factors converts to ICD-9-CM 286.3 (cong def clot factor NEC). The mapping is a direct match.

What HCC is D68.2?

D68.2 (hereditary deficiency of other clotting factors) maps to CMS-HCC Category 112 (Immune Thrombocytopenia and Specified Coagulation Defects and Hemorrhagic Conditions), commonly written as HCC 112, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2026. It mapped to HCC 48 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.

Does D68.2 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, D68.2 adds a risk adjustment factor of about 0.450 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.450 to 0.708 depending on the payment segment). A more severe related category (HCC 111) supersedes it when both are reported. See the full factor table on the HCC 112 category page.