2026 ICD-10-CM Diagnosis Code D68.2Hereditary deficiency of other clotting factors

ICD-10-CM Codes›D50–D89›D65-D69›D68

ICD-10-CM D68.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D68.2 is a billable ICD-10-CM diagnosis code for hereditary deficiency of other clotting factors. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coagulation and hemorrhagic disorders.

Code Identity

ICD-10-CM Code
D68.2
Billable Status
Yes — Valid for Submission
Code Describes
Hereditary deficiency of other clotting factors
Short Description
Hereditary deficiency of other clotting factors
Same as the full description in the CMS dataset.
Parent Code
D68
Other coagulation defects

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD65-D69Coagulation defects, purpura and other hemorrhagic conditions
CategoryD68Other coagulation defects
This CodeD68.2Hereditary deficiency of other clotting factors

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired coagulation factor inhibitor disorder
  • Alpha chain defect dysfibrinogenemia
  • Autosomal dominant deficiency of plasminogen
  • Beta chain defect dysfibrinogenemia
  • Combined deficiency of factor V and factor VIII
  • Congenital afibrinogenemia
  • Congenital fibrinogen abnormality
  • Congenital plasminogen activator inhibitor deficiency type 1
  • Contact factor deficiency
  • Drug-induced coagulation inhibitor disorder
  • Dysfibrinogenemia
  • Dysplasminogenemia
  • Factor I deficiency
  • Factor I deficiency disease
  • Factor II deficiency
  • Factor V deficiency
  • Factor V short isoforms related bleeding disorder
  • Factor VII deficiency
  • Factor X deficiency
  • Factor XII deficiency disease
  • Factor XIII deficiency disease
  • Factor XIII inhibitor disorder
  • Fibrinogen abnormality
  • Fibrinogen deficiency
  • Fibrinogen in blood above reference range
  • Fibrinolytic bleeding syndrome
  • Gamma chain defect dysfibrinogenemia
  • Hemorrhagic disease of the newborn due to factor II deficiency
  • Heparin cofactor II deficiency
  • Hereditary combined coagulation factor deficiency
  • Hereditary combined deficiency of vitamin K-dependent clotting factors
  • Hereditary congenital prekallikrein deficiency
  • Hereditary dysfibrinogenemia
  • Hereditary dysplasminogenemia
  • Hereditary factor I deficiency disease
  • Hereditary factor II deficiency disease
  • Hereditary factor V deficiency disease
  • Hereditary factor VII deficiency disease
  • Hereditary factor X deficiency disease
  • Hereditary factor XII deficiency disease
  • Hereditary factor XIII A subunit and B subunit deficiency
  • Hereditary factor XIII A subunit deficiency
  • Hereditary factor XIII B subunit deficiency
  • Hereditary factor XIII deficiency disease
  • Hereditary hypoplasminogenemia
  • Hereditary thrombophilic dysfibrinogenemia
  • High molecular weight kininogen deficiency
  • Hyperfibrinogenemia
  • Hypodysfibrinogenemia
  • Hypoplasminogenemia
  • Immunodeficiency with factor I anomaly
  • Neonatal coagulation disorder
  • Passovoy factor deficiency
  • Platelet factor V deficiency
  • Platelet procoagulant activity deficiency
  • Prekallikrein deficiency
  • Prothrombin complex deficiency

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • AC globulin deficiency
  • Congenital afibrinogenemia
  • Deficiency of factor I fibrinogen
  • Deficiency of factor II prothrombin
  • Deficiency of factor V labile
  • Deficiency of factor VII stable
  • Deficiency of factor X Stuart-Prower
  • Deficiency of factor XII Hageman
  • Deficiency of factor XIII fibrin stabilizing
  • Dysfibrinogenemia (congenital)
  • Hypoproconvertinemia
  • Owren's disease
  • Proaccelerin deficiency

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Absence(of) (organ or part) (complete or partial)
      • fibrinogen (congenital)
    • Afibrinogenemia
      • congenital
    • Defect, defective
      • coagulation (factor)
        • hereditary NEC
    • Defect, defective
      • fibrin polymerization
    • Defect, defective
      • Hageman (factor)
    • Deficiency, deficient
      • accelerator globulin (Ac G) (blood)
    • Deficiency, deficient
      • AC globulin (congenital) (hereditary)
    • Deficiency, deficient
      • activating factor (blood)
    • Deficiency, deficient
      • autoprothrombin
        • I
    • Deficiency, deficient
      • autoprothrombin
        • C
    • Deficiency, deficient
      • clotting factor NEC (hereditary)
    • Deficiency, deficient
      • coagulation NOS
        • clotting factor NEC
    • Deficiency, deficient
      • contact factor
    • Deficiency, deficient
      • factor
        • Hageman
    • Deficiency, deficient
      • factor
        • I (congenital) (hereditary)
    • Deficiency, deficient
      • factor
        • II (congenital) (hereditary)
    • Deficiency, deficient
      • factor
        • V (congenital) (hereditary)
    • Deficiency, deficient
      • factor
        • VII (congenital) (hereditary)
    • Deficiency, deficient
      • factor
        • X (congenital) (hereditary)
    • Deficiency, deficient
      • factor
        • XII (congenital) (hereditary)
    • Deficiency, deficient
      • factor
        • XIII (congenital) (hereditary)
    • Deficiency, deficient
      • fibrin-stabilizing factor (congenital) (hereditary)
    • Deficiency, deficient
      • fibrinase
    • Deficiency, deficient
      • fibrinogen (congenital) (hereditary)
    • Deficiency, deficient
      • glass factor
    • Deficiency, deficient
      • Hageman factor
    • Deficiency, deficient
      • labile factor (congenital) (hereditary)
    • Deficiency, deficient
      • Laki-Lorand factor
    • Deficiency, deficient
      • proaccelerin (congenital) (hereditary)
    • Deficiency, deficient
      • proconvertin factor (congenital) (hereditary)
    • Deficiency, deficient
      • prothrombin (congenital) (heredItary)
    • Deficiency, deficient
      • Prower factor
    • Deficiency, deficient
      • SPCA (factor VII)
    • Deficiency, deficient
      • stable factor (congenital) (hereditary)
    • Deficiency, deficient
      • Stuart-Prower (factor X)
    • Deficiency, deficient
      • thrombokinase
    • Disease, diseased
      • Hageman (congenital factor XII deficiency)
    • Disease, diseased
      • Stuart-Prower (congenital factor X deficiency)
    • Disease, diseased
      • Stuart's (congenital factor X deficiency)
    • Dysfibrinogenemia(congenital)
    • Fibrinogenopenia
      • congenital
    • Fibrinopenia(hereditary)
    • Hageman's factor defect, deficiency or disease
    • Hypofibrinogenemia
      • congenital (hereditary)
    • Hypoproconvertinemia, congenital(hereditary)
    • Hypoprothrombinemia(congenital) (hereditary) (idiopathic)
    • Owren's disease or syndrome(parahemophilia)
    • Parahemophilia
    • Stuart deficiency disease(factor X)
    • Stuart-Prower factor deficiency(factor X)
    • Syndrome
      • Owren's

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD006
Coagulation and hemorrhagic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Factor VII Deficiency

    an autosomal recessive characteristic or a coagulation disorder acquired in association with vitamin k deficiency. factor vii is a vitamin k dependent glycoprotein essential to the extrinsic pathway of coagulation.

  • Factor V Deficiency

    a deficiency of blood coagulation factor v (known as proaccelerin or accelerator globulin or labile factor) leading to a rare hemorrhagic tendency known as owren's disease or parahemophilia. it varies greatly in severity. factor v deficiency is an autosomal recessive trait. (dorland, 27th ed)

  • Factor X Deficiency

    blood coagulation disorder usually inherited as an autosomal recessive trait, though it can be acquired. it is characterized by defective activity in both the intrinsic and extrinsic pathways, impaired thromboplastin time, and impaired prothrombin consumption.

  • Acquired Factor II Deficiency|Acquired hypoprothrombinemia

    an acquired coagulation disorder characterized by the partial or complete absence of prothrombin (factor ii) activity in the blood.

  • Dysfibrinogenemia

    a coagulation disorder caused by abnormalities in fibrin that result in defective clot formation. this disorder may be inherited or acquired.

  • High Molecular Weight Kininogen Deficiency

    a rare autosomal recessive inherited disorder characterized by prolonged partial thromboplastin time and absence of bleeding diathesis.

  • Acquired Factor VII Deficiency

    an acquired coagulation disorder characterized by the partial or complete absence of factor vii activity in the blood.

  • Factor VII Deficiency

    a coagulation disorder characterized by the partial or complete absence of factor vii activity in the blood.

  • Hereditary Factor VII Deficiency

    a rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of factor vii, resulting in bleeding.

  • Acquired Factor V Deficiency

    an acquired coagulation disorder characterized by the partial or complete absence of factor v activity in the blood.

  • Factor V Deficiency

    a coagulation disorder characterized by the partial or complete absence of factor v activity in the blood.

  • Hereditary Factor V Deficiency|Owren Disease

    a very rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of factor v, resulting in bleeding.

  • Prekallikrein Deficiency

    a condition characterized by the congenital or acquired deficiency of prekallikrein. this deficiency is usually not associated with bleeding. the congenital deficiency is very rare. acquired deficiency may occur in diffuse intravascular coagulation, infections, and sickle cell disease.

  • Acquired Factor II Deficiency

    an acquired coagulation disorder characterized by the partial or complete absence of prothrombin (factor ii) activity in the blood.

  • Factor II Deficiency

    a coagulation disorder characterized by the partial or complete absence of prothrombin (factor ii) activity in the blood.

  • Hereditary Factor II Deficiency|Hereditary Hypoprothrombinemia|Hereditary Prothrombin Deficiency

    a very rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of prothrombin, resulting in bleeding.

  • Acquired Factor X Deficiency

    an acquired coagulation disorder characterized by the partial or complete absence of factor x activity in the blood.

  • Factor X Deficiency

    a coagulation disorder characterized by the partial or complete absence of factor x activity in the blood.

  • Hereditary Factor X Deficiency|Stuart-Prower Factor Deficiency

    a rare autosomal recessive inherited blood coagulation disorder characterized by deficiency of factor x, resulting in bleeding.

Patient EducationClinical

Bleeding Disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D68.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
286.3 Cong def clot factor NEC
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D68.2Overview

Is D68.2 (Other coagulation defects) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hereditary deficiency of other clotting factors on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of D68.2?

Under the General Equivalence Mappings, hereditary deficiency of other clotting factors converts to ICD-9-CM 286.3 (cong def clot factor NEC). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.