ICD-10-CM Code D68.61

Antiphospholipid syndrome

Version 2020 Billable Code

Valid for Submission

D68.61 is a billable code used to specify a medical diagnosis of antiphospholipid syndrome. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code D68.61 might also be used to specify conditions or terms like acquired thrombophilia, antiphospholipid syndrome, antiphospholipid syndrome in pregnancy, catastrophic antiphospholipid syndrome, neonatal antiphospholipid syndrome, primary antiphospholipid syndrome, etc

ICD-10:D68.61
Short Description:Antiphospholipid syndrome
Long Description:Antiphospholipid syndrome

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D68.61:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Anticardiolipin syndrome
  • Antiphospholipid antibody syndrome

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • anti-phospholipid antibody, finding without diagnosis R76.0
  • anti-phospholipid antibody with hemorrhagic disorder D68.312
  • lupus anticoagulant syndrome D68.62

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D68.61 are found in the index:


Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acquired thrombophilia
  • Antiphospholipid syndrome
  • Antiphospholipid syndrome in pregnancy
  • Catastrophic antiphospholipid syndrome
  • Neonatal antiphospholipid syndrome
  • Primary antiphospholipid syndrome
  • Primary antiphospholipid syndrome with multisystem involvement
  • Primary antiphospholipid syndrome with organ/system involvement
  • Secondary antiphospholipid syndrome
  • Secondary antiphospholipid syndrome with multisystem involvement
  • Secondary antiphospholipid syndrome with organ/system involvement
  • Thrombophilia due to antiphospholipid antibody

Clinical Information

  • ANTIPHOSPHOLIPID SYNDROME-. the presence of antibodies directed against phospholipids antibodies antiphospholipid. the condition is associated with a variety of diseases notably systemic lupus erythematosus and other connective tissue diseases thrombopenia and arterial or venous thromboses. in pregnancy it can cause abortion. of the phospholipids the cardiolipins show markedly elevated levels of anticardiolipin antibodies antibodies anticardiolipin. present also are high levels of lupus anticoagulant lupus coagulation inhibitor.

Diagnostic Related Groups

The ICD-10 code D68.61 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2020.

  • 814 - RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH MCC
  • 815 - RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITH CC
  • 816 - RETICULOENDOTHELIAL AND IMMUNITY DISORDERS WITHOUT CC/MCC

Convert D68.61 to ICD-9

  • 289.81 - Prim hypercoagulable st (Approximate Flag)

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)
    • Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)
      • Other coagulation defects (D68)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


Bleeding Disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Bleeding disorders can be the result of other diseases, such as severe liver disease or a lack of vitamin K. They can also be inherited. Hemophilia is an inherited bleeding disorder. Bleeding disorders can also be a side effect of medicines such as blood thinners.

Various blood tests can check for a bleeding disorder. You will also have a physical exam and history. Treatments depend on the cause. They may include medicines and transfusions of blood, platelets, or clotting factor.


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Blood Clots

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. After the bleeding stops and healing takes place, your body usually breaks down and removes the clot. But some people get too many clots or their blood clots abnormally. Many conditions can cause the blood to clot too much or prevent blood clots from dissolving properly.

Risk factors for excessive blood clotting include

  • Certain genetic disorders
  • Atherosclerosis
  • Diabetes
  • Atrial fibrillation
  • Overweight, obesity, and metabolic syndrome
  • Some medicines
  • Smoking
  • Staying in one position for a long time, such as being in the hospital or taking a long car or plane ride
  • Cancer and cancer treatments
Blood clots can form in, or travel to, the blood vessels in the brain, heart, kidneys, lungs, and limbs. A clot in the veins deep in the limbs is called deep vein thrombosis (DVT). DVT usually affects the deep veins of the legs. If a blood clot in a deep vein breaks off and travels through the bloodstream to the lungs and blocks blood flow, it is called a pulmonary embolism. Other complications of blood clots include stroke, heart attack, kidney problems, kidney failure, and pregnancy-related problems. Treatments for blood clots include blood thinners and other medicines.
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Antiphospholipid syndrome Antiphospholipid syndrome is a disorder characterized by an increased tendency to form abnormal blood clots (thromboses) that can block blood vessels. This clotting tendency is known as thrombophilia. In antiphospholipid syndrome, the thromboses can develop in nearly any blood vessel in the body, but most frequently occur in the vessels of the lower limbs. If a blood clot forms in the vessels in the brain, blood flow is impaired and can lead to stroke. Antiphospholipid syndrome is an autoimmune disorder. Autoimmune disorders occur when the immune system attacks the body's own tissues and organs.Women with antiphospholipid syndrome are at increased risk of complications during pregnancy. These complications include pregnancy-induced high blood pressure (preeclampsia), an underdeveloped placenta (placental insufficiency), early delivery, or pregnancy loss (miscarriage). In addition, women with antiphospholipid syndrome are at greater risk of having a thrombosis during pregnancy than at other times during their lives. At birth, infants of mothers with antiphospholipid syndrome may be small and underweight.A thrombosis or pregnancy complication is typically the first sign of antiphospholipid syndrome. This condition usually appears in early to mid-adulthood but can begin at any age.Other signs and symptoms of antiphospholipid syndrome that affect blood cells and vessels include a reduced amount of cell fragments involved in blood clotting called platelets (thrombocytopenia), a shortage of red blood cells (anemia) due to their premature breakdown (hemolysis), and a purplish skin discoloration (livedo reticularis) caused by abnormalities in the tiny blood vessels of the skin. In addition, affected individuals may have open sores (ulcers) on the skin, migraine headaches, heart disease, or intellectual disability. Many people with antiphospholipid syndrome also have other autoimmune disorders such as systemic lupus erythematosus.Rarely, people with antiphospholipid syndrome develop thromboses in multiple blood vessels throughout their body. These thromboses block blood flow in affected organs, which impairs their function and ultimately causes organ failure. These individuals are said to have catastrophic antiphospholipid syndrome (CAPS). CAPS typically affects the kidneys, lungs, brain, heart, and liver, and is fatal in over half of affected individuals. Less than 1 percent of individuals with antiphospholipid syndrome develop CAPS.
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