Disseminated intravascular coagulation [defibrination syndrome] (D65)
ICD-10 code D65disseminated intravascular coagulation (DIC), also known as defibrination syndrome. This condition involves abnormal clotting throughout the blood vessels leading to serious bleeding issues.
The ICD-10 code for disseminated intravascular coagulation covers a range of related conditions characterized by excessive fibrinolysis or clot breakdown. Common synonyms include systemic fibrinogenolysis, hyperfibrinolysis, and purpura fulminans. It also applies to drug-induced fibrinolytic disorders caused by agents like urokinase or tissue plasminogen activator. This code helps medical coders document complex coagulation and hemorrhagic disorders such as acquired fibrinogen abnormalities or consumption coagulopathy from snake venom. Correctly using code D65 ensures accurate classification of this serious disorder, which disrupts normal clot formation and leads to both clotting and severe bleeding problems.
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)
Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)
- D65 Disseminated intravascular coagulation [defibrination syndrome]
Disseminated intravascular coagulation [defibrination syndrome] (D65)
Instructional Notations
Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Afibrinogenemia, acquired
- Consumption coagulopathy
- COVID-19 associated diffuse or disseminated intravascular coagulopathy
- Diffuse or disseminated intravascular coagulation [DIC]
- Fibrinolytic hemorrhage, acquired
- Fibrinolytic purpura
- Purpura fulminans
Code Also
A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.
- , if applicable, associated condition
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- disseminated intravascular coagulation (complicating):
- abortion or ectopic or molar pregnancy O00 O07 O08.1
- in newborn P60
- pregnancy, childbirth and the puerperium O45.0 O46.0 O67.0 O72.3
Clinical Terms
The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.
Afibrinogenemia
A deficiency or absence of FIBRINOGEN in the blood.
Disseminated Intravascular Coagulation
A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.
Fibrinogen
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Purpura Fulminans
A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. Purpura fulminans often accompanies or is triggered by DISSEMINATED INTRAVASCULAR COAGULATION.
Waterhouse-Friderichsen Syndrome
A condition of HEMORRHAGE and NECROSIS of the ADRENAL GLAND. It is characterized by rapidly developing ADRENAL INSUFFICIENCY; HYPOTENSION; and widespread cutaneous PURPURA.
