2024 ICD-10-CM Diagnosis Code D68.59

Other primary thrombophilia

ICD-10-CM Code:
ICD-10 Code for:
Other primary thrombophilia
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Code Navigator:

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    • Coagulation defects, purpura and other hemorrhagic conditions
      • Other coagulation defects

D68.59 is a billable diagnosis code used to specify a medical diagnosis of other primary thrombophilia. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acquired antithrombin III deficiency
  • Acquired heparin cofactor II deficiency
  • Acquired protein C deficiency
  • Acquired protein S deficiency
  • Antithrombin III deficiency
  • Cerebral ischemic stroke due to hypercoagulable state
  • Fibrinogen in blood above reference range
  • Heparin cofactor II deficiency
  • Heparin cofactor II deficiency
  • Hereditary antithrombin III deficiency
  • Hereditary elevated factor VIII
  • Hereditary elevated factor XI
  • Hereditary heparin cofactor II deficiency
  • Hereditary hyperfibrinogenemia
  • Hereditary protein C deficiency
  • Hereditary protein S deficiency
  • Hereditary thrombophilia
  • Hereditary thrombophilia due to congenital histidine-rich glycoprotein deficiency
  • Heterozygous protein C deficiency
  • Heterozygous protein S deficiency
  • Homozygous protein C deficiency
  • Homozygous protein S deficiency
  • Hypercoagulability state
  • Hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency
  • Hyperfibrinogenemia
  • Protein C deficiency disease
  • Protein S deficiency disease
  • Thrombophilia
  • Thrombotic tendency observations
  • Upper gastrointestinal hemorrhage associated with hypercoagulability state

Clinical Classification

Clinical Information

  • Thrombophilia

    a disorder of hemostasis in which there is a tendency for the occurrence of thrombosis.
  • Antithrombin III Deficiency

    an absence or reduced level of antithrombin iii leading to an increased risk for thrombosis.
  • Antithrombin III Deficiency

    a rare disorder characterized by the presence of low levels of antithrombin iii which prohibits the formation of blood clots. it may be inherited, usually in an autosomal dominant pattern, or acquired. it may lead to venous thrombosis and pulmonary embolism.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Antithrombin III deficiency
  • Hypercoagulable state NOS
  • Primary hypercoagulable state NEC
  • Primary thrombophilia NEC
  • Protein C deficiency
  • Protein S deficiency
  • Thrombophilia NOS

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert D68.59 to ICD-9-CM

  • ICD-9-CM Code: 289.81 - Prim hypercoagulable st
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education

Bleeding Disorders

Normally, if you get hurt, your body forms a blood clot to stop the bleeding. For blood to clot, your body needs cells called platelets and proteins known as clotting factors. If you have a bleeding disorder, you either do not have enough platelets or clotting factors or they don't work the way they should.

Bleeding disorders can be the result of other diseases, such as severe liver disease or a lack of vitamin K. They can also be inherited. Hemophilia is an inherited bleeding disorder. Bleeding disorders can also be a side effect of medicines such as blood thinners.

Various blood tests can check for a bleeding disorder. You will also have a physical exam and history. Treatments depend on the cause. They may include medicines and transfusions of blood, platelets, or clotting factor.

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.