Other coagulation defects (D68)

    • ICD-10 Index

      • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)

        • Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)

            • Other coagulation defects (D68)
            • D68 - Other coagulation defects NON-BILLABLE CODE
            • D68.0 - Von Willebrand disease NON-BILLABLE CODE NEW CODE
            • D68.00 - Von Willebrand disease, unspecified BILLABLE CODE NEW CODE
            • D68.01 - Von Willebrand disease, type 1 BILLABLE CODE NEW CODE
            • D68.02 - Von Willebrand disease, type 2 NON-BILLABLE CODE NEW CODE
            • D68.020 - Von Willebrand disease, type 2A BILLABLE CODE NEW CODE
            • D68.021 - Von Willebrand disease, type 2B BILLABLE CODE NEW CODE
            • D68.022 - Von Willebrand disease, type 2M BILLABLE CODE NEW CODE
            • D68.023 - Von Willebrand disease, type 2N BILLABLE CODE NEW CODE
            • D68.029 - Von Willebrand disease, type 2, unspecified BILLABLE CODE NEW CODE
            • D68.03 - Von Willebrand disease, type 3 BILLABLE CODE NEW CODE
            • D68.04 - Acquired von Willebrand disease BILLABLE CODE NEW CODE
            • D68.09 - Other von Willebrand disease BILLABLE CODE NEW CODE
            • D68.1 - Hereditary factor XI deficiency BILLABLE CODE
            • D68.2 - Hereditary deficiency of other clotting factors BILLABLE CODE
            • D68.3 - Hemorrhagic disorder due to circulating anticoagulants NON-BILLABLE CODE
            • D68.31 - Hemorrhagic disorder due to intrns circ anticoag,antib,inhib NON-BILLABLE CODE
            • D68.311 - Acquired hemophilia BILLABLE CODE
            • D68.312 - Antiphospholipid antibody with hemorrhagic disorder BILLABLE CODE
            • D68.318 - Oth hemorrhagic disord d/t intrns circ anticoag,antib,inhib BILLABLE CODE
            • D68.32 - Hemorrhagic disord d/t extrinsic circulating anticoagulants BILLABLE CODE
            • D68.4 - Acquired coagulation factor deficiency BILLABLE CODE
            • D68.5 - Primary thrombophilia NON-BILLABLE CODE
            • D68.51 - Activated protein C resistance BILLABLE CODE
            • D68.52 - Prothrombin gene mutation BILLABLE CODE
            • D68.59 - Other primary thrombophilia BILLABLE CODE
            • D68.6 - Other thrombophilia NON-BILLABLE CODE
            • D68.61 - Antiphospholipid syndrome BILLABLE CODE
            • D68.62 - Lupus anticoagulant syndrome BILLABLE CODE
            • D68.69 - Other thrombophilia BILLABLE CODE
            • D68.8 - Other specified coagulation defects BILLABLE CODE
            • D68.9 - Coagulation defect, unspecified BILLABLE CODE

Clinical Information for Other coagulation defects (D68)

Antiphospholipid Syndrome - The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).

Thrombophilia - A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.

Activated Protein C Resistance - A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.

Thrombophilia - A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.

Factor VII Deficiency - An autosomal recessive characteristic or a coagulation disorder acquired in association with VITAMIN K DEFICIENCY. FACTOR VII is a Vitamin K dependent glycoprotein essential to the extrinsic pathway of coagulation.

Factor V Deficiency - A deficiency of blood coagulation factor V (known as proaccelerin or accelerator globulin or labile factor) leading to a rare hemorrhagic tendency known as Owren's disease or parahemophilia. It varies greatly in severity. Factor V deficiency is an autosomal recessive trait. (Dorland, 27th ed)

Factor X Deficiency - Blood coagulation disorder usually inherited as an autosomal recessive trait, though it can be acquired. It is characterized by defective activity in both the intrinsic and extrinsic pathways, impaired thromboplastin time, and impaired prothrombin consumption.

Factor XI Deficiency - A hereditary deficiency of blood coagulation factor XI (also known as plasma thromboplastin antecedent or PTA or antihemophilic factor C) resulting in a systemic blood-clotting defect called hemophilia C or Rosenthal's syndrome, that may resemble classical hemophilia.

Factor VII Deficiency - An autosomal recessive characteristic or a coagulation disorder acquired in association with VITAMIN K DEFICIENCY. FACTOR VII is a Vitamin K dependent glycoprotein essential to the extrinsic pathway of coagulation.

Factor V Deficiency - A deficiency of blood coagulation factor V (known as proaccelerin or accelerator globulin or labile factor) leading to a rare hemorrhagic tendency known as Owren's disease or parahemophilia. It varies greatly in severity. Factor V deficiency is an autosomal recessive trait. (Dorland, 27th ed)

Vitamin K Deficiency - A nutritional condition produced by a deficiency of VITAMIN K in the diet, characterized by an increased tendency to hemorrhage (HEMORRHAGIC DISORDERS). Such bleeding episodes may be particularly severe in newborn infants. (From Cecil Textbook of Medicine, 19th ed, p1182)

Vitamin K Deficiency Bleeding - Hemorrhage caused by vitamin K deficiency.

Factor X Deficiency - Blood coagulation disorder usually inherited as an autosomal recessive trait, though it can be acquired. It is characterized by defective activity in both the intrinsic and extrinsic pathways, impaired thromboplastin time, and impaired prothrombin consumption.

Factor XI Deficiency - A hereditary deficiency of blood coagulation factor XI (also known as plasma thromboplastin antecedent or PTA or antihemophilic factor C) resulting in a systemic blood-clotting defect called hemophilia C or Rosenthal's syndrome, that may resemble classical hemophilia.

Menorrhagia - Excessive uterine bleeding during MENSTRUATION.

Antiphospholipid Syndrome - The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).

Afibrinogenemia - A deficiency or absence of FIBRINOGEN in the blood.

Thrombophilia - A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.

Antithrombin III Deficiency - An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis.

Fibrinogen - Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

Menstruation - The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.

Instructional Notations

Type 1 Excludes Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

  • abnormal coagulation profile NOS R79.1

Type 2 Excludes Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

  • coagulation defects complicating abortion or ectopic or molar pregnancy O00 O07 O08.1
  • coagulation defects complicating pregnancy, childbirth and the puerperium O45.0 O46.0 O67.0 O72.3