Other coagulation defects (D68) ICD-10-CM
The D68 code range covers other coagulation defects with 32 ICD-10-CM diagnosis codes. 25 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- abnormal coagulation profile NOS R79.1
Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Codes in the D68 Range 32 codes · 25 billable
- D68 Other coagulation defectsNon-billable
- D68.0 Von Willebrand diseaseNon-billable
- D68.00 Von Willebrand disease, unspecified
- D68.01 Von Willebrand disease, type 1
- D68.02 Von Willebrand disease, type 2Non-billable
- D68.020 Von Willebrand disease, type 2A
- D68.021 Von Willebrand disease, type 2B
- D68.022 Von Willebrand disease, type 2M
- D68.023 Von Willebrand disease, type 2N
- D68.029 Von Willebrand disease, type 2, unspecified
- D68.03 Von Willebrand disease, type 3
- D68.04 Acquired von Willebrand disease
- D68.09 Other von Willebrand disease
- D68.1 Hereditary factor XI deficiency
- D68.2 Hereditary deficiency of other clotting factors
- D68.3 Hemorrhagic disorder due to circulating anticoagulantsNon-billable
- D68.31 Hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitorsNon-billable
- D68.311 Acquired hemophilia
- D68.312 Antiphospholipid antibody with hemorrhagic disorder
- D68.318 Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors
- D68.32 Hemorrhagic disorder due to extrinsic circulating anticoagulants
- D68.4 Acquired coagulation factor deficiency
- D68.5 Primary thrombophiliaNon-billable
- D68.51 Activated protein C resistance
- D68.52 Prothrombin gene mutation
- D68.59 Other primary thrombophilia
- D68.6 Other thrombophiliaNon-billable
- D68.61 Antiphospholipid syndrome
- D68.62 Lupus anticoagulant syndrome
- D68.69 Other thrombophilia
- D68.8 Other specified coagulation defects
- D68.9 Coagulation defect, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the D68 range.
Activated Protein C Resistance
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.
Afibrinogenemia
A deficiency or absence of FIBRINOGEN in the blood.
Antiphospholipid Syndrome
The presence of antibodies directed against phospholipids (ANTIBODIES, ANTIPHOSPHOLIPID). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (ANTIBODIES, ANTICARDIOLIPIN). Present also are high levels of lupus anticoagulant (LUPUS COAGULATION INHIBITOR).
Antithrombin III Deficiency
An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis.
Factor V Deficiency
A deficiency of blood coagulation factor V (known as proaccelerin or accelerator globulin or labile factor) leading to a rare hemorrhagic tendency known as Owren's disease or parahemophilia. It varies greatly in severity. Factor V deficiency is an autosomal recessive trait. (Dorland, 27th ed)
Factor VII Deficiency
An autosomal recessive characteristic or a coagulation disorder acquired in association with VITAMIN K DEFICIENCY. FACTOR VII is a Vitamin K dependent glycoprotein essential to the extrinsic pathway of coagulation.
Factor X Deficiency
Blood coagulation disorder usually inherited as an autosomal recessive trait, though it can be acquired. It is characterized by defective activity in both the intrinsic and extrinsic pathways, impaired thromboplastin time, and impaired prothrombin consumption.
Factor XI Deficiency
A hereditary deficiency of blood coagulation factor XI (also known as plasma thromboplastin antecedent or PTA or antihemophilic factor C) resulting in a systemic blood-clotting defect called hemophilia C or Rosenthal's syndrome, that may resemble classical hemophilia.
Fibrinogen
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
Menorrhagia
Excessive uterine bleeding during MENSTRUATION.
Menstruation
The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.
Thrombophilia
A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.
Vitamin K Deficiency
A nutritional condition produced by a deficiency of VITAMIN K in the diet, characterized by an increased tendency to hemorrhage (HEMORRHAGIC DISORDERS). Such bleeding episodes may be particularly severe in newborn infants. (From Cecil Textbook of Medicine, 19th ed, p1182)
Vitamin K Deficiency Bleeding
Hemorrhage caused by vitamin K deficiency.
About the D68 Code Range
The ICD-10 code section D68 covers a range of other coagulation defects, including various forms of von Willebrand disease and hereditary or acquired clotting factor deficiencies. These codes are used to identify specific bleeding and clotting disorders that affect blood coagulation beyond common hemophilias.
This section includes detailed classifications such as D68.0 for von Willebrand disease, which has subtypes like type 1 (hereditary von Willebrand disease type 1) and acquired forms as well. For medical coders, recognizing synonyms like "von Willebrand disorder" or "von Willebrand factor below reference range" helps properly assign codes for bleeding disorders affecting platelet function and clotting. Other codes, such as D68.1 and D68.2, cover hereditary factor XI deficiency and deficiencies of other clotting factors, often linked with extensive lists of synonyms to ensure accurate coding of rare bleeding disorders.
The section also encompasses hemorrhagic disorders caused by circulating anticoagulants (D68.3), acquired coagulation factor deficiencies (D68.4), and primary thrombophilias (D68.5), including conditions like activated protein C resistance (Factor V Leiden mutation) and prothrombin gene mutations. Antiphospholipid syndrome (D68.61) and lupus anticoagulant syndrome (D68.62) are important autoimmune-related coagulation disorders coded here. Code D68.8 includes other specified coagulation defects, while D68.9 is for unspecified coagulation defects, covering various bleeding tendencies such as menorrhagia due to coagulopathy. Using the ICD-10 code for these conditions ensures precise medical documentation and billing for diverse coagulation disorders.
Questions About This Page
How many billable codes are in the D68 range?
Of the 32 codes in this range, 25 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the D68 range classify?
The range classifies other coagulation defects. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
