2026 ICD-10-CM Diagnosis Code D59.9Acquired hemolytic anemia, unspecified

ICD-10-CM Codes›D50–D89›D55-D59›D59

ICD-10-CM D59.9
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D59.9 is a billable ICD-10-CM diagnosis code for acquired hemolytic anemia, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 808 through 810. Coders also document this condition as acquired hemolytic anemia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic anemia.

Code Identity

ICD-10-CM Code
D59.9
Billable Status
Yes — Valid for Submission
Code Describes
Acquired hemolytic anemia, unspecified
Short Description
Acquired hemolytic anemia, unspecified
Same as the full description in the CMS dataset.
Parent Code
D59
Acquired hemolytic anemia

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD55-D59Hemolytic anemias
CategoryD59Acquired hemolytic anemia
This CodeD59.9Acquired hemolytic anemia, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired hemolytic anemia
  • Acquired hemolytic anemia co-occurrent with human immunodeficiency virus infection
  • Anemia in mother complicating pregnancy, childbirth AND/OR puerperium
  • Anemia of pregnancy
  • Hemoglobinemia
  • Hemolytic anemia of pregnancy
  • Hemolytic jaundice
  • Infantile pyknocytosis
  • Pyknocytosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Idiopathic hemolytic anemia, chronic

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • chronic
        • hemolytic
          • idiopathic
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • hemolytic
        • acquired
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • hemolytic
        • acute
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • hemolytic
        • chronic
          • idiopathic
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • hemolytic
        • idiopathic (chronic)
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • idiopathic
        • hemolytic, chronic
    • Hemoglobinemia
    • Icteroanemia, hemolytic(acquired)
    • Icterus
      • hematogenous (acquired)
    • Icterus
      • hemolytic (acquired)
    • Jaundice(yellow)
      • hematogenous
    • Jaundice(yellow)
      • hemolytic (acquired)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD002
Hemolytic anemia
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Acquired Hemolytic Anemia

    hemolytic anemia, the cause of which is not present at birth.

  • Hemolytic Jaundice

    jaundice occurring as a result of red blood cell rupture.

Patient EducationClinical

Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D59.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
283.9 Acq hemolytic anemia NOS
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D59.9Overview

Is D59.9 (Acquired hemolytic anemia) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report acquired hemolytic anemia, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D59.9 group to?

When acquired hemolytic anemia, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 808, 809, 810, with relative weights from 1.0466 to 2.2079 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D59.9?

Under the General Equivalence Mappings, acquired hemolytic anemia, unspecified converts to ICD-9-CM 283.9 (acq hemolytic anemia NOS). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.