2021 ICD-10-CM Code D59

Acquired hemolytic anemia

Version 2021
Non-Billable Code

Not Valid for Submission

D59 is a "header" nonspecific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of acquired hemolytic anemia. The code is NOT valid for the year 2021 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Short Description:Acquired hemolytic anemia
Long Description:Acquired hemolytic anemia

Code Classification

Specific Coding for Acquired hemolytic anemia

Header codes like D59 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for acquired hemolytic anemia:

  • D59.0 - Drug-induced autoimmune hemolytic anemia
  • D59.1 - Other autoimmune hemolytic anemias
  • D59.10 - Autoimmune hemolytic anemia, unspecified
  • D59.11 - Warm autoimmune hemolytic anemia
  • D59.12 - Cold autoimmune hemolytic anemia
  • D59.13 - Mixed type autoimmune hemolytic anemia
  • D59.19 - Other autoimmune hemolytic anemia
  • D59.2 - Drug-induced nonautoimmune hemolytic anemia
  • D59.3 - Hemolytic-uremic syndrome
  • D59.4 - Other nonautoimmune hemolytic anemias
  • D59.5 - Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
  • D59.6 - Hemoglobinuria due to hemolysis from other external causes
  • D59.8 - Other acquired hemolytic anemias
  • D59.9 - ... unspecified

Clinical Information

Information for Patients


Also called: Iron poor blood

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute

[Learn More in MedlinePlus]

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)