Version 2024

2024 ICD-10-CM Diagnosis Code D59

Acquired hemolytic anemia

ICD-10-CM Code:
ICD-10 Code for:
Acquired hemolytic anemia
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    • Hemolytic anemias
      • Acquired hemolytic anemia

D59 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of acquired hemolytic anemia. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Acquired hemolytic anemia

Non-specific codes like D59 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for acquired hemolytic anemia:

  • Use D59.0 for Drug-induced autoimmune hemolytic anemia - BILLABLE CODE

  • D59.1 for Other autoimmune hemolytic anemias - NON-BILLABLE CODE

  • Use D59.10 for Autoimmune hemolytic anemia, unspecified - BILLABLE CODE

  • Use D59.11 for Warm autoimmune hemolytic anemia - BILLABLE CODE

  • Use D59.12 for Cold autoimmune hemolytic anemia - BILLABLE CODE

  • Use D59.13 for Mixed type autoimmune hemolytic anemia - BILLABLE CODE

  • Use D59.19 for Other autoimmune hemolytic anemia - BILLABLE CODE

  • Use D59.2 for Drug-induced nonautoimmune hemolytic anemia - BILLABLE CODE

  • D59.3 for Hemolytic-uremic syndrome - NON-BILLABLE CODE

  • Use D59.30 for Hemolytic-uremic syndrome, unspecified - BILLABLE CODE

  • Use D59.31 for Infection-associated hemolytic-uremic syndrome - BILLABLE CODE

  • Use D59.32 for Hereditary hemolytic-uremic syndrome - BILLABLE CODE

  • Use D59.39 for Other hemolytic-uremic syndrome - BILLABLE CODE

  • Use D59.4 for Other nonautoimmune hemolytic anemias - BILLABLE CODE

  • Use D59.5 for Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli] - BILLABLE CODE

  • Use D59.6 for Hemoglobinuria due to hemolysis from other external causes - BILLABLE CODE

  • Use D59.8 for Other acquired hemolytic anemias - BILLABLE CODE

  • Use D59.9 for Acquired hemolytic anemia, unspecified - BILLABLE CODE

Clinical Information

  • Acquired Hemolytic Anemia

    hemolytic anemia, the cause of which is not present at birth.

Patient Education


If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include:

  • Heavy periods
  • Pregnancy
  • Ulcers
  • Colon polyps or colon cancer
  • Inherited disorders
  • A diet that does not have enough iron, folic acid or vitamin B12
  • Blood disorders such as sickle cell anemia and thalassemia, or cancer
  • Aplastic anemia, a condition that can be inherited or acquired
  • G6PD deficiency, a metabolic disorder

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.