MS-DRG 810 – Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC
A Medical DRG in MDC 16 (Diseases & Disorders of Blood, Blood Forming Organs, Immunologic Disorders). Inpatient cases group to DRG 810 when the ICD-10-CM principal diagnosis is one of the 63 codes listed below and no secondary diagnosis on the CC or MCC lists is present. Its FY 2026 relative weight is 1.0466 with a geometric mean length of stay of 2.6 days.
Severity family
The grouper first assigns the case to MDC 16 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 808; with CC → 809; without CC/MCC → 810.
Principal Diagnosis Codes 63 codes · 12 categories
D59 Acquired hemolytic anemia12 codes
- D59.0 Drug-induced autoimmune hemolytic anemia
- D59.10 Autoimmune hemolytic anemia, unspecified
- D59.11 Warm autoimmune hemolytic anemia
- D59.12 Cold autoimmune hemolytic anemia
- D59.13 Mixed type autoimmune hemolytic anemia
- D59.19 Other autoimmune hemolytic anemia
- D59.2 Drug-induced nonautoimmune hemolytic anemia
- D59.4 Other nonautoimmune hemolytic anemias
- D59.5 Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
- D59.6 Hemoglobinuria due to hemolysis from other external causes
- D59.8 Other acquired hemolytic anemias
- D59.9 Acquired hemolytic anemia, unspecified
D60 Acquired pure red cell aplasia [erythroblastopenia]4 codes
D61 Other aplastic anemias and other bone marrow failure syndromes12 codes
- D61.01 Constitutional (pure) red blood cell aplasia
- D61.02 Shwachman-Diamond syndrome
- D61.03 Fanconi anemia
- D61.09 Other constitutional aplastic anemia
- D61.1 Drug-induced aplastic anemia
- D61.2 Aplastic anemia due to other external agents
- D61.3 Idiopathic aplastic anemia
- D61.810 Antineoplastic chemotherapy induced pancytopenia
- D61.811 Other drug-induced pancytopenia
- D61.818 Other pancytopenia
- D61.89 Other specified aplastic anemias and other bone marrow failure syndromes
- D61.9 Aplastic anemia, unspecified
D70 Neutropenia7 codes
D71 Functional disorders of polymorphonuclear neutrophils3 codes
D72 Other disorders of white blood cells1 code
- D72.0 Genetic anomalies of leukocytes
D80 Immunodeficiency with predominantly antibody defects3 codes
D81 Combined immunodeficiencies9 codes
- D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
- D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
- D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
- D81.4 Nezelof's syndrome
- D81.6 Major histocompatibility complex class I deficiency
- D81.7 Major histocompatibility complex class II deficiency
- D81.82 Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
- D81.89 Other combined immunodeficiencies
- D81.9 Combined immunodeficiency, unspecified
D82 Immunodeficiency associated with other major defects2 codes
D89 Other disorders involving the immune mechanism, not elsewhere classified4 codes
I27 Other pulmonary heart diseases1 code
- I27.841 Fontan-associated lymphatic dysfunction
Procedure Codes
Frequently Asked Questions
What is MS-DRG 810?
MS-DRG 810 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC) is a medical DRG in MDC 16 (Diseases & Disorders of Blood, Blood Forming Organs, Immunologic Disorders). Its FY 2026 relative weight is 1.0466 with a geometric mean length of stay of 2.6 days.
What is the difference between DRG 808, 809, 810?
All 3 share the same base category; the severity of secondary diagnoses separates them: 808 (with MCC), 809 (with CC), 810 (without CC/MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.
How many diagnosis codes group to DRG 810?
63 ICD-10-CM principal diagnosis codes group to this DRG, spanning 12 three-character categories.
What is the relative weight of DRG 810?
The FY 2026 relative weight of this DRG is 1.0466, meaning reimbursement of roughly 1.05 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.
