Other hereditary hemolytic anemias (D58) ICD-10-CM
The D58 code range covers other hereditary hemolytic anemias with 6 ICD-10-CM diagnosis codes. 5 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- hemolytic anemia of the newborn P55
Codes in the D58 Range 6 codes · 5 billable
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the D58 range.
Hemoglobin C Disease
A disease characterized by compensated hemolysis with a normal hemoglobin level or a mild to moderate anemia. There may be intermittent abdominal discomfort, splenomegaly, and slight jaundice.
Hemoglobinopathies
A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
Pseudoxanthoma Elasticum
An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.
About the D58 Code Range
The ICD-10 code section D58 covers other hereditary hemolytic anemias, a group of genetic blood disorders where red blood cells break down prematurely. This section includes various specific conditions distinguished by their unique causes and characteristics.
The code D58.0 represents hereditary spherocytosis, sometimes called "anemia due to membrane defect" or "spherocytosis," characterized by abnormally shaped red blood cells. D58.1 is for hereditary elliptocytosis, also known as "elliptocytosis," involving elliptical-shaped red cells often linked to protein deficiencies. The D58.2 code includes a range of other hemoglobinopathies such as "hemoglobin C disease" or "unstable hemoglobin disease," related to mutations in hemoglobin structure affecting oxygen transport. D58.8 describes other specified hereditary hemolytic anemias like hereditary stomatocytosis and xerocytosis, which have distinct membrane or metabolic defects. Finally, D58.9 is used when the hereditary hemolytic anemia is unspecified, covering cases labeled as "congenital hemolytic anemia" without further detail. These codes assist in accurately classifying inherited hemolytic anemias for diagnosis, treatment, and medical coding purposes.
Questions About This Page
How many billable codes are in the D58 range?
Of the 6 codes in this range, 5 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the D58 range classify?
The range classifies other hereditary hemolytic anemias. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
