Acquired hemolytic anemia (D59) ICD-10-CM
The D59 code range covers acquired hemolytic anemia with 19 ICD-10-CM diagnosis codes. 16 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Codes in the D59 Range 19 codes · 16 billable
- D59 Acquired hemolytic anemiaNon-billable
- D59.0 Drug-induced autoimmune hemolytic anemia
- D59.1 Other autoimmune hemolytic anemiasNon-billable
- D59.10 Autoimmune hemolytic anemia, unspecified
- D59.11 Warm autoimmune hemolytic anemia
- D59.12 Cold autoimmune hemolytic anemia
- D59.13 Mixed type autoimmune hemolytic anemia
- D59.19 Other autoimmune hemolytic anemia
- D59.2 Drug-induced nonautoimmune hemolytic anemia
- D59.3 Hemolytic-uremic syndromeNon-billable
- D59.30 Hemolytic-uremic syndrome, unspecified
- D59.31 Infection-associated hemolytic-uremic syndrome
- D59.32 Hereditary hemolytic-uremic syndrome
- D59.39 Other hemolytic-uremic syndrome
- D59.4 Other nonautoimmune hemolytic anemias
- D59.5 Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
- D59.6 Hemoglobinuria due to hemolysis from other external causes
- D59.8 Other acquired hemolytic anemias
- D59.9 Acquired hemolytic anemia, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the D59 range.
Acquired Hemolytic Anemia
Hemolytic anemia, the cause of which is not present at birth.
Anemia, Hemolytic, Autoimmune
Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.
Hemolytic-Uremic Syndrome
A syndrome that is associated with microvascular diseases of the KIDNEY, such as RENAL CORTICAL NECROSIS. It is characterized by hemolytic anemia (ANEMIA, HEMOLYTIC); THROMBOCYTOPENIA; and ACUTE RENAL FAILURE.
Warm Antibody Autoimmune Hemolytic Anemia
The most common form of autoimmune hemolytic anemia, in which the autoantibodies react with red blood cells at temperatures greater than or equal to 37 degrees Celsius.
About the D59 Code Range
Acquired hemolytic anemia is hemolytic anemia whose cause is not present at birth. The D59 category groups these conditions by type or cause.
Drug-induced anemia separates into autoimmune D59.0 and nonautoimmune D59.2 forms. Other autoimmune anemia divides into warm, cold, mixed, unspecified and other types under D59.1. Hemolytic-uremic syndrome divides into infection-associated, hereditary, unspecified and other forms under D59.3.
The remaining subdivisions identify other nonautoimmune hemolytic anemias, paroxysmal nocturnal hemoglobinuria, and hemoglobinuria due to hemolysis from other external causes. They also provide other and unspecified acquired hemolytic anemia codes.
Questions About This Page
How many billable codes are in the D59 range?
Of the 19 codes in this range, 16 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the D59 range classify?
The range classifies acquired hemolytic anemia. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
