2026 ICD-10-CM Diagnosis Code D55.0Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
ICD-10-CM Codes›D50–D89›D55-D59›D55
- Billable — Valid for Submission
- Chronic Condition
D55.0 is a billable ICD-10-CM diagnosis code for anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 811 through 812. Coders also document this condition as deficiency of glucose-6-phosphate dehydrogenase. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic anemia.
D55.0 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 48 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 48, ESRD (V21) category 48, and ESRD (V24) category 48 for payment year 2026.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
D55.0 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.
Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Deficiency of glucose-6-phosphate dehydrogenase
- Favism
- G-6-PD class I variant anemia
- G-6-PD class II variant anemia
- G-6-PD class III variant anemia
- G-6-PD class IV variant anemia
- G-6-PD class V variant anemia
- G-6-PD variant enzyme deficiency anemia
- Glucose-6-phosphate dehydrogenase deficiency anemia
- Severe deficiency of glucose-6-phosphate dehydrogenase
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Favism
- G6PD deficiency anemia
Type 1 Excludes
- glucose-6-phosphate dehydrogenase G6PD deficiency without anemia D75.A
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
Baghdad spring D55.0
G6PD D55.0
favism D55.0
Favism (anemia) D55.0
Poisoning (acute) See Also: Table of Drugs and Chemicals;
fava bean D55.0
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Favism
hemolytic anemia due to the ingestion of fava beans or after inhalation of pollen from the vicia fava plant by persons with glucose-6-phosphate dehydrogenase deficient erythrocytes.Favism
a condition associated with glucose-6-phosphate dehydrogenase deficiency, which is characterized by hemolysis.
Patient EducationClinical
Anemia
If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D55.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D55.0Overview
What is the ICD-10 code for anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency?
The ICD-10-CM code for anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency is D55.0 (sometimes written as D550). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Is D55.0 (Anemia due to enzyme disorders) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does D55.0 group to?
When anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency is the principal diagnosis on an inpatient stay, it groups to MS-DRG 811, 812, with relative weights from 0.9182 to 1.4043 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of D55.0?
Under the General Equivalence Mappings, anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency converts to ICD-9-CM 282.2 (glutathione dis anemia). The mapping is approximate, so confirm the match fits the documentation.
Does D55.0 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage. D55.0 mapped to HCC 48 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 48 (Coagulation Defects and Other Specified Hematological Disorders), ESRD (V21) category 48 (Coagulation Defects and Other Specified Hematological Disorders), and ESRD (V24) category 48 (Coagulation Defects and Other Specified Hematological Disorders).
