ICD-10-CM Code D56

Thalassemia

Version 2021 Non-Billable Code

Not Valid for Submission

D56 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of thalassemia. The code is NOT valid for the year 2021 for the submission of HIPAA-covered transactions.

ICD-10:D56
Short Description:Thalassemia
Long Description:Thalassemia

Consider the following ICD-10 codes with a higher level of specificity:

  • D56.0 - Alpha thalassemia
  • D56.1 - Beta thalassemia
  • D56.2 - Delta-beta thalassemia
  • D56.3 - Thalassemia minor
  • D56.4 - Hereditary persistence of fetal hemoglobin [HPFH]
  • D56.5 - Hemoglobin E-beta thalassemia
  • D56.8 - Other thalassemias
  • D56.9 - ... unspecified

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D56:

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • sickle-cell thalassemia D57.4

Clinical Information

  • THALASSEMIA-. a group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. there are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.
  • ALPHA THALASSEMIA-. a disorder characterized by reduced synthesis of the alpha chains of hemoglobin. the severity of this condition can vary from mild anemia to death depending on the number of genes deleted.
  • BETA THALASSEMIA-. a disorder characterized by reduced synthesis of the beta chains of hemoglobin. there is retardation of hemoglobin a synthesis in the heterozygous form thalassemia minor which is asymptomatic while in the homozygous form thalassemia major cooley's anemia mediterranean anemia erythroblastic anemia which can result in severe complications and even death hemoglobin a synthesis is absent.

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Thalassemia

Also called: Cooley's anemia, Mediterranean anemia

Thalassemias are inherited blood disorders. If you have one, your body makes fewer healthy red blood cells and less hemoglobin. Hemoglobin is a protein that carries oxygen to the body. That leads to anemia. Thalassemias occur most often among people of Italian, Greek, Middle Eastern, Southern Asian, and African descent.

Thalassemias can be mild or severe. Some people have no symptoms or mild anemia. The most common severe type in the United States is called Cooley's anemia. It usually appears during the first two years of life. People with it may have severe anemia, slowed growth and delayed puberty, and problems with the spleen, liver, heart, or bones.

Doctors diagnose thalassemias using blood tests. Treatments include blood transfusions and treatment to remove excess iron from the body. If you have mild symptoms or no symptoms, you may not need treatment. In some severe cases, you may need a bone marrow transplant.

NIH: National Heart, Lung, and Blood Institute

  • Thalassemia (Medical Encyclopedia)

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