2026 ICD-10-CM Diagnosis Code E88.2Lipomatosis, not elsewhere classified

ICD-10-CM CodesE00–E89E70-E88E88

ICD-10-CM E88.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E88.2 is a billable ICD-10-CM diagnosis code for lipomatosis, not elsewhere classified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E88.2
Billable Status
Yes — Valid for Submission
Code Describes
Lipomatosis, not elsewhere classified
Short Description
Lipomatosis, not elsewhere classified
Same as the full description in the CMS dataset.
Parent Code
Other and unspecified metabolic disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE88Other and unspecified metabolic disorders
This CodeE88.2Lipomatosis, not elsewhere classified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Adiposis tuberosa simplex
  • Congenital diffuse lipomatosis
  • Congenital infiltrating lipomatosis of face
  • Encephalocraniocutaneous lipomatosis
  • Epidural lipomatosis
  • Familial multiple lipomata
  • Familial multiple lipomatosis
  • Fat hypertrophy
  • Hemihyperplasia with multiple lipomatosis syndrome
  • Hereditary disorder of lymphatic system
  • Lipoma of skin
  • Lipomatosis
  • Lipomatosis circumscripta
  • Lipomatosis dolorosa
  • Lipomatosis of subcutaneous tissue
  • Lipomatosis renis
  • Multiple lipomata
  • Multiple symmetrical lipomatosis
  • Nodular circumscribed lipomatosis
  • Perineural lipomatosis
  • Pierpont syndrome
  • PTEN hamartoma tumor syndrome
  • Roch Leri mesosomatous lipomatosis
  • Segmental outgrowth, lipomatosis, arteriovenous malformation, epidermal nevus syndrome
  • Subcutaneous lipoma

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Lipomatosis NOS
  • Lipomatosis (Check) dolorosa Dercum

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Adiposis
      • dolorosa
    • Dercum's disease
    • Lipomatosis
    • Lipomatosis
      • dolorosa (Dercum)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Adiposis Dolorosa

    a rare disease characterized by multiple tumor-like fatty deposits that press on nerves in various sites causing pain and weakness. often these lipoma-like structures are located on the trunk and limbs but not on the face and hands.
  • Familial Multiple Lipomatosis

    a rare autosomal disorder characterized by numerous encapsulated lipomas on the trunk and extremities. the lipomas are usually not painful but can cause pain when growing. in rare cases, one lipoma can become painful and progress to multiple painful lipomas; it is then referred to as dercum's disease type iii
  • Lipoma

    a benign tumor composed of fat cells (adipocytes). it can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.
  • Lipomatosis

    a disorder characterized by the accumulation of encapsulated or unencapsulated tumor-like fatty tissue resembling lipoma.
  • Lipomatosis, Multiple Symmetrical

    a condition characterized by the growth of unencapsulated masses of adipose tissue symmetrically deposited around the neck, shoulders, or other sites around the body.
  • Adipocytes

    cells in the body that store fats, usually in the form of triglycerides. white adipocytes are the predominant type and found mostly in the abdominal cavity and subcutaneous tissue. brown adipocytes are thermogenic cells that can be found in newborns of some species and hibernating mammals.
  • Adipose Tissue

    specialized connective tissue composed of fat cells (adipocytes). it is the site of stored fats, usually in the form of triglycerides. in mammals, there are two types of adipose tissue, the white fat and the brown fat. their relative distributions vary in different species with most adipose tissue being white.

Patient EducationClinical

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E88.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
272.8 Lipoid metabol dis NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E88.2Overview

Is E88.2 (Other and unspecified metabolic disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report lipomatosis, not elsewhere classified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of E88.2?

Under the General Equivalence Mappings, lipomatosis, not elsewhere classified converts to ICD-9-CM 272.8 (lipoid metabol dis NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.