2027 ICD-10-CM Diagnosis Code E88.2Lipomatosis, not elsewhere classified
ICD-10-CM Codes›E00–E89›E70-E88›E88
- Billable — Valid for Submission
- Chronic Condition
E88.2 is a billable ICD-10-CM diagnosis code for lipomatosis, not elsewhere classified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 642. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.
E88.2 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 47 for payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
E88.2 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model, but it maps to payment categories in the other CMS models shown below.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Adiposis tuberosa simplex
- Congenital diffuse lipomatosis
- Congenital infiltrating lipomatosis of face
- Encephalocraniocutaneous lipomatosis
- Epidural lipomatosis
- Familial multiple lipomata
- Familial multiple lipomatosis
- Fat hypertrophy
- Hemihyperplasia with multiple lipomatosis syndrome
- Hereditary disorder of lymphatic system
- Lipoma of skin
- Lipomatosis
- Lipomatosis circumscripta
- Lipomatosis dolorosa
- Lipomatosis of subcutaneous tissue
- Lipomatosis renis
- Multiple lipomata
- Multiple symmetrical lipomatosis
- Nodular circumscribed lipomatosis
- Perineural lipomatosis
- Pierpont syndrome
- PTEN hamartoma tumor syndrome
- Roch Leri mesosomatous lipomatosis
- Segmental outgrowth, lipomatosis, arteriovenous malformation, epidermal nevus syndrome
- Subcutaneous lipoma
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E88.2: its own notes plus those printed at E88, block E70-E88, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Lipomatosis NOS
- Lipomatosis (Check) dolorosa [Dercum]
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- histiocytosis X (chronic) (C96.6)
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- Ehlers-Danlos syndromes (Q79.6-)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- codes for associated conditions
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name E88.2, its category, or a range that includes it.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Dercum's disease E88.2
Lipomatosis E88.2
dolorosa (Dercum) E88.2
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Lipomatosis
a disorder characterized by the accumulation of encapsulated or unencapsulated tumor-like fatty tissue resembling lipoma.
Patient EducationClinical
Metabolic Disorders
Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E88.2 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E88.2Overview
What is the ICD-10 code for lipomatosis, not elsewhere classified?
The ICD-10-CM code for lipomatosis, not elsewhere classified is E88.2 (sometimes written as E882). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E88.2 (Other and unspecified metabolic disorders) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report lipomatosis, not elsewhere classified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E88.2 group to?
When lipomatosis, not elsewhere classified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 642 (inborn and Other Disorders of Metabolism), which carries a relative weight of 1.3226. Higher weights mean higher Medicare reimbursement.
Can E88.2 be reported with C96.6?
Not as a rule. The Excludes1 note at E88, which applies to E88.2, lists "histiocytosis X (chronic) (C96.6)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
Does E88.2 need an additional code?
When the condition applies, yes. The Use Additional Code note at E88, which applies to E88.2, reads: codes for associated conditions. The additional code is reported after E88.2.
Does E88.2 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage: E88.2 maps to no category in the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 47 (Disorders of Lipoid Metabolism).
