2026 ICD-10-CM Diagnosis Code E34.50Androgen insensitivity syndrome, unspecified

ICD-10-CM Codes›E00–E89›E20-E35›E34

ICD-10-CM E34.50
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E34.50 is a billable ICD-10-CM diagnosis code for androgen insensitivity syndrome, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E34.50
Billable Status
Yes — Valid for Submission
Code Describes
Androgen insensitivity syndrome, unspecified
Short Description
Androgen insensitivity syndrome, unspecified
Same as the full description in the CMS dataset.
Parent Code
E34.5
Androgen insensitivity syndrome

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE34Other endocrine disorders
This CodeE34.50Androgen insensitivity syndrome, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Androgen receptor absent
  • Androgen resistance syndrome
  • Disorder of androgen receptor
  • Drug-induced feminization
  • Feminization
  • Feminization due to tumor
  • Feminized male
  • Infertile male syndrome
  • Male infertility of developmental origin
  • Male pseudohermaphroditism
  • Mild androgen insensitivity syndrome
  • Partial androgen insensitivity syndrome
  • Stromal cell hyperplasia in androgen insensitivity syndrome
  • Testicular lesion in androgen insensitivity syndrome

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Androgen insensitivity NOS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Androgen insensitivity syndrome
    • Androgen resistance syndrome
    • Disorder(of)
      • receptor, hormonal, peripheral
    • Insensitivity
      • androgen
    • Syndrome
      • androgen insensitivity
    • Syndrome
      • androgen resistance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Androgen-Insensitivity Syndrome

    a disorder of sexual development transmitted as an x-linked recessive trait. these patients have a karyotype of 46,xy with end-organ resistance to androgen due to mutations in the androgen receptor (receptors, androgen) gene. severity of the defect in receptor quantity or quality correlates with their phenotypes. in these genetic males, the phenotypic spectrum ranges from those with normal female external genitalia, through those with genital ambiguity as in reifenstein syndrome, to that of a normal male with infertility.

  • Feminization

    development of female secondary sex characteristics in the male. it is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as adrenal glands or therapeutic drugs.

Patient EducationClinical

Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E34.50 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
259.50 Androgen insensitvty NOS
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E34.50Overview

Is E34.50 (Androgen insensitivity syndrome) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report androgen insensitivity syndrome, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E34.50 group to?

When androgen insensitivity syndrome, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E34.50?

Under the General Equivalence Mappings, androgen insensitivity syndrome, unspecified converts to ICD-9-CM 259.50 (androgen insensitvty NOS). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.