2027 ICD-10-CM Diagnosis Code E34.50Androgen insensitivity syndrome, unspecified
ICD-10-CM Codes›E00–E89›E20-E35›E34
- Billable — Valid for Submission
- Chronic Condition
E34.50 is a billable ICD-10-CM diagnosis code for androgen insensitivity syndrome, unspecified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Androgen receptor absent
- Androgen resistance syndrome
- Disorder of androgen receptor
- Drug-induced feminization
- Feminization
- Feminization due to neoplasm
- Feminized male
- Infertile male syndrome
- Male infertility of developmental origin
- Male pseudohermaphroditism
- Mild androgen insensitivity syndrome
- Partial androgen insensitivity syndrome
- Stromal cell hyperplasia in androgen insensitivity syndrome
- Testicular lesion in androgen insensitivity syndrome
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E34.50: its own notes plus those printed at E34, block E20-E35, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Androgen insensitivity NOS
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name E34.50, its category, or a range that includes it.
Excludes1 4
These codes carry an Excludes1 note naming E34.50: they are not reported together with it, unless the two conditions are unrelated.
- E29 Testicular dysfunctionandrogen insensitivity syndrome (E34.5-) names E34.5-, which includes this code
- Block E70-E88 Metabolic disordersandrogen insensitivity syndrome (E34.5-) names E34.5-, which includes this code
- Block Q50-Q56 Congenital malformations of genital organsandrogen insensitivity syndrome (E34.5-) names E34.5-, which includes this code
- Q56 Indeterminate sex and pseudohermaphroditismandrogen insensitivity syndrome (E34.5-) names E34.5-, which includes this code
Code First 1
These codes say to code first a condition named in the note, and E34.50 is one of the conditions named.
- G63 Polyneuropathy in diseases classified elsewhere
Notes 1
These notes mention E34.50.
- Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseasesAll neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere. names E34.-, which includes this code
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Androgen insensitivity syndrome See Also: Syndrome, androgen insensitivity; E34.50
Androgen resistance syndrome See Also: Syndrome, androgen insensitivity; E34.50
Disorder (of) See Also: Disease;
receptor, hormonal, peripheral See Also: Syndrome, androgen insensitivity; E34.50
androgen E34.50
Syndrome See Also: Disease;
androgen insensitivity E34.50
androgen resistance See Also: Syndrome, androgen insensitivity; E34.50
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Androgen-Insensitivity Syndrome
a disorder of sexual development transmitted as an x-linked recessive trait. these patients have a karyotype of 46,xy with end-organ resistance to androgen due to mutations in the androgen receptor (receptors, androgen) gene. severity of the defect in receptor quantity or quality correlates with their phenotypes. in these genetic males, the phenotypic spectrum ranges from those with normal female external genitalia, through those with genital ambiguity as in reifenstein syndrome, to that of a normal male with infertility.
Patient EducationClinical
Endocrine Diseases
Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E34.50 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E34.50Overview
What is the ICD-10 code for androgen insensitivity syndrome, unspecified?
The ICD-10-CM code for androgen insensitivity syndrome, unspecified is E34.50 (sometimes written as E3450). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E34.50 (Androgen insensitivity syndrome) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report androgen insensitivity syndrome, unspecified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E34.50 group to?
When androgen insensitivity syndrome, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.
Can E34.50 be reported with E20.1?
Not as a rule. The Excludes1 note at E34, which applies to E34.50, lists "pseudohypoparathyroidism (E20.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of E34.50?
Under the General Equivalence Mappings, androgen insensitivity syndrome, unspecified converts to ICD-9-CM 259.50 (androgen insensitvty NOS). The mapping is a direct match.
