2026 ICD-10-CM Diagnosis Code E28.319Asymptomatic premature menopause

ICD-10-CM Codes›E00–E89›E20-E35›E28

ICD-10-CM E28.319
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E28.319 is a billable ICD-10-CM diagnosis code for asymptomatic premature menopause. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 742 through 743, 760 through 761. The code is restricted by the Medicare Code Editor to adult patients (age 15 through 124). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Female infertility, Menopausal disorders, and Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E28.319
Billable Status
Yes — Valid for Submission
Code Describes
Asymptomatic premature menopause
Short Description
Asymptomatic premature menopause
Same as the full description in the CMS dataset.
Parent Code
E28.31
Premature menopause

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE28Ovarian dysfunction
This CodeE28.319Asymptomatic premature menopause

Code EditsBilling

Medicare Code Editor checks that affect claim validity for E28.319.

Adult diagnoses
The Medicare Code Editor detects inconsistencies in adult cases by checking a patient's age and any diagnosis on the patient's record. The adult code edits apply to patients age range is 15–124 years inclusive (e.g., senile delirium, mature cataract).

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Asymptomatic premature menopause
  • Micromelia
  • Polyneuropathy, intellectual disability, acromicria, premature menopause syndrome
  • Premature menopause
  • Premature ovarian failure

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Premature menopause NOS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Menopause, menopausal(asymptomatic) (state)
      • premature
    • Menopause, menopausal(asymptomatic) (state)
      • premature
        • asymptomatic
    • Premature
      • menopause
    • Premature
      • menopause
        • asymptomatic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR GEN024
Female infertility
Default principal diagnosis: inpatient No · outpatient No
CCSR GEN023
Menopausal disorders
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Menopause

Menopause is the time in your life when you stop having your period and can no longer get pregnant. You have reached menopause when you have not had a period for 12 months.

The full article covers:

  • What is menopause?
  • What is early menopause?
  • What are the symptoms of menopause?
  • What are the treatments for the symptoms of menopause?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E28.319 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
256.31 Premature menopause
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E28.319Overview

Is E28.319 (Premature menopause) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report asymptomatic premature menopause on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E28.319 group to?

When asymptomatic premature menopause is the principal diagnosis on an inpatient stay, it groups to MS-DRG 742, 743, 760, 761, with relative weights from 0.5696 to 1.8348 depending on complications. Higher weights mean higher Medicare reimbursement.

Who can E28.319 be reported for?

The Medicare Code Editor checks asymptomatic premature menopause against patient demographics: this code is intended for adult patients (age 15 through 124). Claims outside these limits are flagged as inconsistent.

What is the ICD-9 equivalent of E28.319?

Under the General Equivalence Mappings, asymptomatic premature menopause converts to ICD-9-CM 256.31 (premature menopause). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.