2026 ICD-10-CM Diagnosis Code D59.6Hemoglobinuria due to hemolysis from other external causes
ICD-10-CM Codes›D50–D89›D55-D59›D59
- Billable — Valid for Submission
- Chronic Condition
D59.6 is a billable ICD-10-CM diagnosis code for hemoglobinuria due to hemolysis from other external causes. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 808 through 810. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic anemia.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Hemoglobinuria - external causation
- Hemoglobinuria due to hemolysis from external causes
- Idiopathic paroxysmal cold hemoglobinuria
- March hemoglobinuria
- Paroxysmal cold hemoglobinuria
- Paroxysmal cold hemoglobinuria associated with tertiary syphilis
- Post-viral paroxysmal cold hemoglobinuria
- Primary autoimmune hemolytic anemia
- Secondary autoimmune hemolytic anemia
- Secondary paroxysmal cold hemoglobinuria
- Sports anemia
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Hemoglobinuria from exertion
- March hemoglobinuria
- Paroxysmal cold hemoglobinuria
Use Additional Code
- code (Chapter 20) to identify external cause
Type 1 Excludes
- hemoglobinuria NOS R82.3
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) - D64.9
- with hemoglobinuria NEC - D59.6
- Disease, diseased - See Also: Syndrome;
- cold
- agglutinin or hemoglobinuria - D59.12
- paroxysmal - D59.6
- Harley's disease - D59.6
- Hemoglobinemia - D59.9
- paroxysmal - D59.6
- Hemoglobinuria - R82.3
- due to exertion or hemolysis NEC - D59.6
- intermittent - D59.6
- march - D59.6
- paroxysmal (cold) - D59.6
- March
- hemoglobinuria - D59.6
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
- hemolytic
- acquired
- with hemoglobinuria NEC
- Disease, diseased
- cold
- agglutinin or hemoglobinuria
- paroxysmal
- Harley's disease
- Hemoglobinemia
- paroxysmal
- Hemoglobinuria
- with anemia, hemolytic, acquired (chronic) NEC
- Hemoglobinuria
- cold (paroxysmal) (with Raynaud's syndrome)
- Hemoglobinuria
- due to exertion or hemolysis NEC
- Hemoglobinuria
- intermittent
- Hemoglobinuria
- march
- Hemoglobinuria
- paroxysmal (cold)
- March
- hemoglobinuria
- Murri's disease(intermittent hemoglobinuria)
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Hemoglobinuria due to Hemolysis from External Causes
hemoglobin in the urine that is due to hemolysis from an external cause.
Patient EducationClinical
Anemia
If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D59.6 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D59.6Overview
Is D59.6 (Acquired hemolytic anemia) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report hemoglobinuria due to hemolysis from other external causes on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does D59.6 group to?
When hemoglobinuria due to hemolysis from other external causes is the principal diagnosis on an inpatient stay, it groups to MS-DRG 808, 809, 810, with relative weights from 1.0466 to 2.2079 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of D59.6?
Under the General Equivalence Mappings, hemoglobinuria due to hemolysis from other external causes converts to ICD-9-CM 283.2 (hemolytic hemoglobinuria). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
