Version 2024
No Valid Principal Dx

2024 ICD-10-CM Diagnosis Code R82.3


ICD-10-CM Code:
ICD-10 Code for:
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
    • Abnormal findings on examination of urine, without diagnosis
      • Other and unspecified abnormal findings in urine

R82.3 is a billable diagnosis code used to specify a medical diagnosis of hemoglobinuria. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acquired hemoglobinopathy
  • Acquired methemoglobinuria
  • Carboxyhemoglobinuria
  • Hemoglobinuria
  • Hemoglobinuria
  • Methemoglobinuria
  • Postparturient hemoglobinuria
  • Sulfhemoglobinuria

Clinical Classification

Clinical Information

  • Hemoglobinuria

    the presence of free hemoglobin in the urine, indicating hemolysis of erythrocytes within the vascular system. after saturating the hemoglobin-binding proteins (haptoglobins), free hemoglobin begins to appear in the urine.
  • Hemoglobinuria, Paroxysmal

    a condition characterized by the recurrence of hemoglobinuria caused by intravascular hemolysis. in cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. in cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
  • Blackwater Fever|Malarial Hemoglobinuria

    a complication of malaria resulting from hemolysis.
  • Grade 1 Hemoglobinuria, CTCAE|Grade 1 Hemoglobinuria|Grade 1 Hemoglobinuria

    asymptomatic; clinical or diagnostic observations only; intervention not indicated
  • Hemoglobinuria

    a laboratory test result which indicates free hemoglobin in the urine.
  • Hemoglobinuria due to Hemolysis from External Causes

    hemoglobin in the urine that is due to hemolysis from an external cause.
  • Hemoglobinuria, CTCAE 5.0|Hemoglobinuria|Hemoglobinuria

    a disorder characterized by laboratory test results that indicate the presence of free hemoglobin in the urine.
  • Paroxysmal Nocturnal Hemoglobinuria|PNH|PNH|Paroxysmal Hemoglobinuria|paroxysmal nocturnal hemoglobinuria

    a rare acquired hematologic disorder characterized by hemolytic anemia, dark-colored urine due to the release of hemoglobin in the blood, and thrombosis. the episodes of hemolysis tend to occur at night. it is caused by a somatic mutation in the glycosylphosphatidylinositol biosynthesis gene.
  • PIGA Gene Mutation|GPI3 Gene Mutation|MCAHS2 Gene Mutation|PIG-A Gene Mutation|PNH1 Gene Mutation|Paroxysmal Nocturnal Hemoglobinuria Gene Mutation|Phosphatidylinositol Glycan Anchor Biosynthesis Class A Gene Mutation

    a change in the nucleotide sequence of the piga gene.
  • PIGA wt Allele|GPI3|MCAHS2|PIG-A|PNH1|Paroxysmal Nocturnal Hemoglobinuria Gene|Phosphatidylinositol Glycan Anchor Biosynthesis Class A wt Allele|Phosphatidylinositol Glycan Anchor Biosynthesis, Class A Gene|Phosphatidylinositol Glycan, Class A (Paroxysmal Nocturnal Hemoglobinuria) Gene

    human piga wild-type allele is located in the vicinity of xp22.1 and is approximately 16 kb in length. this allele, which encodes phosphatidylinositol n-acetylglucosaminyltransferase subunit a protein, plays a role in the modulation of protein lipidation. mutation of the gene is associated with paroxysmal nocturnal hemoglobinuria.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • hemoglobinuria due to hemolysis from external causes NEC D59.6
  • hemoglobinuria due to paroxysmal nocturnal Marchiafava-Micheli D59.5

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert R82.3 to ICD-9-CM

  • ICD-9-CM Code: 791.2 - Hemoglobinuria

Patient Education

Urine and Urination

Your kidneys make urine by filtering wastes and extra water from your blood. The waste is called urea. Your blood carries it to the kidneys. From the kidneys, urine travels down two thin tubes called ureters to the bladder. The bladder stores urine until you are ready to urinate. It swells into a round shape when it is full and gets smaller when empty. If your urinary system is healthy, your bladder can hold up to 16 ounces (2 cups) of urine comfortably for 2 to 5 hours.

You may have problems with urination if you have:

  • Kidney failure
  • Urinary tract infections
  • An enlarged prostate
  • Bladder control problems like incontinence, overactive bladder, or interstitial cystitis
  • A blockage that prevents you from emptying your bladder

Some conditions may also cause you to have blood or protein in your urine. If you have a urinary problem, see your health care provider. Urinalysis and other urine tests can help to diagnose the problem. Treatment depends on the cause.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.