2027 ICD-10-CM Diagnosis Code D59.13Mixed type autoimmune hemolytic anemia

ICD-10-CM Codes›D50–D89›D55-D59›D59

ICD-10-CM D59.13
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D59.13 is a billable ICD-10-CM diagnosis code for mixed type autoimmune hemolytic anemia. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 808 through 810. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 16 closely related codes. Coders also document this condition as autoimmune hemolytic anemia mixed type. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic anemia.

For Medicare Advantage risk adjustment, D59.13 maps to CMS-HCC Category 109 (Acquired Hemolytic, Aplastic, and Sideroblastic Anemias) under the V28 model, adding a risk factor of about 1.144 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
D59.13
Billable Status
Yes — Valid for Submission
Code Describes
Mixed type autoimmune hemolytic anemia
Short Description
Mixed type autoimmune hemolytic anemia
Same as the full description in the CMS dataset.
Parent Code
D59.1
Other autoimmune hemolytic anemias

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD55-D59Hemolytic anemias
CategoryD59Acquired hemolytic anemia
This CodeD59.13Mixed type autoimmune hemolytic anemia

Medicare Risk Adjustment (HCC)Billing

D59.13 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 109— Acquired Hemolytic, Aplastic, and Sideroblastic Anemias
Payment HCC · PY 2027 one of 37 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+1.144
community, non-dual, aged · ranges 0.529–1.815 across segments
Hierarchy
Top of its hierarchy
HCC 109 is not superseded by any other condition category
Prior Model (CMS-HCC V24)
HCC 46
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 46 · ESRD (V21): HCC 46 · ESRD (V24): HCC 46
ESRD V21 weights: 0.180 dialysis, 0.766–1.325 functioning graft · ESRD V24 weights: 0.223 dialysis, 0.748–4.064 functioning graft
Part D (RxHCC)
RxHCC 96 — Acquired Hemolytic, Aplastic, and Sideroblastic Anemias
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Autoimmune hemolytic anemia mixed type
  • Chronic hemolytic anemia
  • Warm autoimmune hemolytic anemia

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D59.13: its own notes plus those printed at D59.1 and Chapter 3. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Mixed type autoimmune hemolytic disease
  • Mixed type, cold and warm, (primary) (secondary) (symptomatic) autoimmune hemolytic anemia

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From D59.1 Other autoimmune hemolytic anemias applies to 5 codes
  • Evans syndrome (D69.41)
  • hemolytic disease of newborn (P55.-)
  • paroxysmal cold hemoglobinuria (D59.6)
From Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism applies to 324 codes
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD002
Hemolytic anemia
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Acquired Hemolytic Anemia

    hemolytic anemia, the cause of which is not present at birth.

Patient EducationClinical

Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement D59.13 replaces the following previously assigned code(s):

  • D59.1 - Other autoimmune hemolytic anemias
FY 2021AddedAdded to the ICD-10-CM code setEffective October 1, 2020.
FY 2022–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D59.13Overview

What is the ICD-10 code for mixed type autoimmune hemolytic anemia?

The ICD-10-CM code for mixed type autoimmune hemolytic anemia is D59.13 (sometimes written as D5913). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D59.13 (Other autoimmune hemolytic anemias) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report mixed type autoimmune hemolytic anemia on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D59.13 group to?

When mixed type autoimmune hemolytic anemia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 808, 809, 810, with relative weights from 1.0749 to 2.1706 depending on complications. Higher weights mean higher Medicare reimbursement.

Is D59.13 a CC or MCC?

CMS lists D59.13 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 16 closely related codes in its exclusion list.

What HCC is D59.13?

D59.13 (mixed type autoimmune hemolytic anemia) maps to CMS-HCC Category 109 (Acquired Hemolytic, Aplastic, and Sideroblastic Anemias), commonly written as HCC 109, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 46 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 96.

Does D59.13 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, D59.13 adds a risk adjustment factor of about 1.144 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.529 to 1.815 depending on the payment segment). HCC 109 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 109 category page.