2027 ICD-10-CM Diagnosis Code P55Hemolytic disease of newborn

ICD-10-CM Codes›P00–P96›P50-P61›P55

ICD-10-CM P55
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

P55 is a non-billable ICD-10-CM category code for hemolytic disease of newborn, so it cannot be submitted on claims. Use a more specific code from this category instead, such as P55.0, P55.1, P55.8, and P55.9.

Code Identity

ICD-10-CM Code
P55
Billable Status
No — Non-Billable Category
Code Describes
Hemolytic disease of newborn
Short Description
Hemolytic disease of newborn
Same as the full description in the CMS dataset.
Chapter
P50-P61
Hemorrhagic and hematological disorders of newborn

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP50-P61Hemorrhagic and hematological disorders of newborn
CategoryP55Hemolytic disease of newborn
This CodeP55Hemolytic disease of newborn

Specific Coding for Hemolytic disease of newbornOverview

Non-specific codes like P55 require more characters. Use one of these billable codes instead:

  • Use P55.0 for Rh isoimmunization of newborn

  • Use P55.1 for ABO isoimmunization of newborn

  • Use P55.8 for Other hemolytic diseases of newborn

  • Use P55.9 for Hemolytic disease of newborn, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to P55: its own notes plus those printed at block P50-P61 and Chapter 16. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block P50-P61 Hemorrhagic and hematological disorders of newborn applies to 67 codes
  • congenital stenosis and stricture of bile ducts (Q44.3)
  • Crigler-Najjar syndrome (E80.5)
  • Dubin-Johnson syndrome (E80.6)
  • Gilbert syndrome (E80.4)
  • hereditary hemolytic anemias (D55-D58)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • tetanus neonatorum (A33)

Notes

General instructions on how these codes are used.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • Codes from this chapter are for use on newborn records only, never on maternal records

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name P55, its category, or a range that includes it.

Excludes1 6

These codes carry an Excludes1 note naming P55: they are not reported together with it, unless the two conditions are unrelated.

  • D58 Other hereditary hemolytic anemias
    hemolytic anemia of the newborn (P55.-)
  • K72 Hepatic failure, not elsewhere classified
    icterus of newborn (P55-P59)
  • P58 Neonatal jaundice due to other excessive hemolysis
    jaundice due to isoimmunization (P55-P57)
  • R17 Unspecified jaundice
    neonatal jaundice (P55, P57-P59)
  • R71 Abnormality of red blood cells
    newborn anemia due to isoimmunization (P55.-)
  • R76.0 Raised antibody titer
    isoimmunization affecting newborn (P55.-)

Excludes2 2

These codes carry an Excludes2 note naming P55: its condition is not part of those codes, and both may be reported when the patient has both.

  • D59.1 Other autoimmune hemolytic anemias
    hemolytic disease of newborn (P55.-)
  • Block R70-R79 Abnormal findings on examination of blood, without diagnosis
    hemorrhagic and hematological disorders of newborn (P50-P61) names P50-P61, which includes this code

Code Also 1

These codes say P55 may also be needed to fully describe the condition. The note gives no sequencing direction.

Clinical InformationClinical

  • Erythroblastosis, Fetal

    a condition characterized by the abnormal presence of erythroblasts in the circulation of the fetus or newborns. it is a disorder due to blood group incompatibility, such as the maternal alloimmunization by fetal antigen rh factors leading to hemolysis of erythrocytes, hemolytic anemia (anemia, hemolytic), general edema (hydrops fetalis), and severe jaundice in newborn.

Patient EducationClinical

Blood Disorders

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About P55Overview

What is the ICD-10 code for hemolytic disease of newborn?

P55 is the ICD-10-CM category for hemolytic disease of newborn, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is P55 (Hemolytic disease of newborn) a billable code?

No. This is a category header that groups the codes for hemolytic disease of newborn, and headers cannot be submitted on claims. Claims for hemolytic disease of newborn need a more specific code from this category, such as P55.0, P55.1, and P55.8.

Can P55 be reported with Q44.3?

Not as a rule. The Excludes1 note at block P50-P61, which applies to P55, lists "congenital stenosis and stricture of bile ducts (Q44.3)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).