ICD-10-CM Code D58.2

Other hemoglobinopathies

Version 2020 Billable Code

Valid for Submission

D58.2 is a billable code used to specify a medical diagnosis of other hemoglobinopathies. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code D58.2 might also be used to specify conditions or terms like acquired hemoglobinopathy, central cyanosis, hemoglobin c disease, hemoglobin c trait, hemoglobin d disease, hemoglobin d trait, etc

Short Description:Other hemoglobinopathies
Long Description:Other hemoglobinopathies

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D58.2:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Abnormal hemoglobin NOS
  • Congenital Heinz body anemia
  • Hb-C disease
  • Hb-D disease
  • Hb-E disease
  • Hemoglobinopathy NOS
  • Unstable hemoglobin hemolytic disease

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • familial polycythemia D75.0
  • Hb-M disease D74.0
  • hemoglobin E-beta thalassemia D56.5
  • hereditary persistence of fetal hemoglobin HPFH D56.4
  • high-altitude polycythemia D75.1
  • methemoglobinemia D74
  • other hemoglobinopathies with thalassemia D56.8

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D58.2 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acquired hemoglobinopathy
  • Central cyanosis
  • Hemoglobin C disease
  • Hemoglobin C trait
  • Hemoglobin D disease
  • Hemoglobin D trait
  • Hemoglobin E disease
  • Hemoglobin E trait
  • Hemoglobin O-Arab trait
  • Hemoglobin very high
  • Hemoglobin Zurich disease
  • Hemoglobinopathy
  • Hemoglobinopathy with cyanosis
  • Hemoglobinopathy with erythrocytosis
  • Hereditary hemoglobinopathy
  • Hereditary hemoglobinopathy due to globin chain mutation
  • Heterozygous hemoglobinopathy
  • High affinity hemoglobin
  • Homozygous hemoglobinopathy
  • Increased hemoglobin
  • Low affinity hemoglobin
  • Mixed hemoglobin disorder
  • Osteonecrosis due to hemoglobinopathy
  • Unstable hemoglobin disease

Clinical Information

  • HEMOGLOBINOPATHIES-. a group of inherited disorders characterized by structural alterations within the hemoglobin molecule.

Diagnostic Related Groups

The ICD-10 code D58.2 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2019 through 09/30/2020.


Convert D58.2 to ICD-9

  • 282.7 - Hemoglobinopathies NEC (Approximate Flag)

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)
    • Hemolytic anemias (D55-D59)
      • Other hereditary hemolytic anemias (D58)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include

  • Heavy periods
  • Pregnancy
  • Ulcers
  • Colon polyps or colon cancer
  • Inherited disorders
  • A diet that does not have enough iron, folic acid or vitamin B12
  • Blood disorders such as sickle cell anemia and thalassemia, or cancer
  • Aplastic anemia, a condition that can be inherited or acquired
  • G6PD deficiency, a metabolic disorder

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute

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