2026 ICD-10-CM Diagnosis Code D58.8Other specified hereditary hemolytic anemias

ICD-10-CM Codes›D50–D89›D55-D59›D58

ICD-10-CM D58.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D58.8 is a billable ICD-10-CM diagnosis code for other specified hereditary hemolytic anemias. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 811 through 812. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic anemia.

Code Identity

ICD-10-CM Code
D58.8
Billable Status
Yes — Valid for Submission
Code Describes
Other specified hereditary hemolytic anemias
Short Description
Other specified hereditary hemolytic anemias
Same as the full description in the CMS dataset.
Parent Code
D58
Other hereditary hemolytic anemias

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD55-D59Hemolytic anemias
CategoryD58Other hereditary hemolytic anemias
This CodeD58.8Other specified hereditary hemolytic anemias

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Anemia due to membrane defect
  • Congenital nonspherocytic hemolytic anemia due to inborn error of metabolism
  • Coombs negative hemolytic anemia
  • Dehydrated hereditary stomatocytosis
  • Familial hemolytic uremic syndrome
  • Familial pseudohyperkalemia
  • Hereditary cryohydrocytosis with normal stomatin
  • Hereditary cryohydrocytosis with reduced stomatin
  • Hereditary elliptocytosis
  • Hereditary pyropoikilocytosis
  • Hereditary stomatocytosis
  • HNSHA due to decreased adenosine deaminase activity
  • Overhydrated hereditary stomatocytosis
  • Rh deficiency syndrome
  • Stomatocytosis
  • Xerocytosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Stomatocytosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • hemolytic
        • hereditary
          • specified type NEC
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • hemolytic
        • specified (hereditary) type NEC
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • hemolytic
        • Stransky-Regala type
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • stomatocytosis
    • Decrease(d)
      • fragility of erythrocytes
    • Stomatocytosis
    • Syndrome
      • hyperviscosity ( of serum)
        • sclerothymic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD002
Hemolytic anemia
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hereditary Pyropoikilocytosis

    an autosomal recessive inherited severe hemolytic anemia. it is a subtype of hereditary elliptocytosis and is characterized by partial spectrin deficiency.

  • Stomatocytosis

    a condition where red blood cells have a central slit-like appearance.

Patient EducationClinical

Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D58.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
282.8 Hered hemolytic anem NEC
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D58.8Overview

Is D58.8 (Other hereditary hemolytic anemias) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other specified hereditary hemolytic anemias on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D58.8 group to?

When other specified hereditary hemolytic anemias is the principal diagnosis on an inpatient stay, it groups to MS-DRG 811, 812, with relative weights from 0.9182 to 1.4043 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D58.8?

Under the General Equivalence Mappings, other specified hereditary hemolytic anemias converts to ICD-9-CM 282.8 (hered hemolytic anem NEC). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.