2026 ICD-10-CM Diagnosis Code D58.8Other specified hereditary hemolytic anemias
ICD-10-CM Codes›D50–D89›D55-D59›D58
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Chronic Condition
D58.8 is a billable ICD-10-CM diagnosis code for other specified hereditary hemolytic anemias. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 811 through 812. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 104 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic anemia.
D58.8 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 48 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 48, ESRD (V21) category 48, and ESRD (V24) category 48 for payment year 2026.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
D58.8 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.
Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Anemia due to membrane defect
- Congenital nonspherocytic hemolytic anemia due to inborn error of metabolism
- Coombs negative hemolytic anemia
- Dehydrated hereditary stomatocytosis
- Familial hemolytic uremic syndrome
- Familial pseudohyperkalemia
- Hereditary cryohydrocytosis with normal stomatin
- Hereditary cryohydrocytosis with reduced stomatin
- Hereditary elliptocytosis
- Hereditary pyropoikilocytosis
- Hereditary stomatocytosis
- HNSHA due to decreased adenosine deaminase activity
- Overhydrated hereditary stomatocytosis
- Rh deficiency syndrome
- Stomatocytosis
- Xerocytosis
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Stomatocytosis
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
specified type NEC D58.8
Stransky-Regala type See Also: Hemoglobinopathy; D58.8
stomatocytosis D58.8
Stomatocytosis D58.8
Syndrome See Also: Disease;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Hereditary Pyropoikilocytosis
an autosomal recessive inherited severe hemolytic anemia. it is a subtype of hereditary elliptocytosis and is characterized by partial spectrin deficiency.Stomatocytosis
a condition where red blood cells have a central slit-like appearance.
Patient EducationClinical
Anemia
If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D58.8 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D58.8Overview
What is the ICD-10 code for other specified hereditary hemolytic anemias?
The ICD-10-CM code for other specified hereditary hemolytic anemias is D58.8 (sometimes written as D588). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Is D58.8 (Other hereditary hemolytic anemias) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other specified hereditary hemolytic anemias on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does D58.8 group to?
When other specified hereditary hemolytic anemias is the principal diagnosis on an inpatient stay, it groups to MS-DRG 811, 812, with relative weights from 0.9182 to 1.4043 depending on complications. Higher weights mean higher Medicare reimbursement.
Is D58.8 a CC or MCC?
CMS lists D58.8 as a CC (complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 104 closely related codes in its exclusion list.
What is the ICD-9 equivalent of D58.8?
Under the General Equivalence Mappings, other specified hereditary hemolytic anemias converts to ICD-9-CM 282.8 (hered hemolytic anem NEC). The mapping is a direct match.
Does D58.8 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage. D58.8 mapped to HCC 48 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 48 (Coagulation Defects and Other Specified Hematological Disorders), ESRD (V21) category 48 (Coagulation Defects and Other Specified Hematological Disorders), and ESRD (V24) category 48 (Coagulation Defects and Other Specified Hematological Disorders).
