2027 ICD-10-CM Diagnosis Code E75.6Lipid storage disorder, unspecified
ICD-10-CM Codes›E00–E89›E70-E88›E75
- Billable — Valid for Submission
- Chronic Condition
E75.6 is a billable ICD-10-CM diagnosis code for lipid storage disorder, unspecified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 642. Coders also document this condition as abnormal lipid deposits. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.
E75.6 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 43 for payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
E75.6 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model, but it maps to payment categories in the other CMS models shown below.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Abnormal lipid deposits
- Cerebral degeneration associated with generalized lipidosis
- Hereditary retinal dystrophies in lipidoses
- Kidney disease due to genetic disorder of lipid storage
- Lipid storage disease
- Lipid storage myopathy
- Lipoidosis
- Mitochondrial-lipid-glycogen storage myopathy
- Retinal dystrophy in cerebroretinal lipidosis
- Retinal dystrophy in systemic lipidosis
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E75.6: its own notes plus those printed at E75, block E70-E88, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- Ehlers-Danlos syndromes (Q79.6-)
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name E75.6, its category, or a range that includes it.
Excludes1 1
These codes carry an Excludes1 note naming E75.6: they are not reported together with it, unless the two conditions are unrelated.
Code First 2
These codes say to code first a condition named in the note, and E75.6 is one of the conditions named.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disease, diseased See Also: Syndrome;
lipid-storage E75.6
Disorder (of) See Also: Disease;
Hyperlipidosis E75.6
Lipidosis E75.6
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Lipidoses
conditions characterized by abnormal lipid deposition due to disturbance in lipid metabolism, such as hereditary diseases involving lysosomal enzymes required for lipid breakdown. they are classified either by the enzyme defect or by the type of lipid involved.
Patient EducationClinical
Metabolic Disorders
Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E75.6 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E75.6Overview
What is the ICD-10 code for lipid storage disorder, unspecified?
The ICD-10-CM code for lipid storage disorder, unspecified is E75.6 (sometimes written as E756). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E75.6 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report lipid storage disorder, unspecified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E75.6 group to?
When lipid storage disorder, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 642 (inborn and Other Disorders of Metabolism), which carries a relative weight of 1.3226. Higher weights mean higher Medicare reimbursement.
Can E75.6 be reported with G60.1?
Not as a rule. The Excludes1 note at E75, which applies to E75.6, lists "Refsum's disease (G60.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of E75.6?
Under the General Equivalence Mappings, lipid storage disorder, unspecified converts to ICD-9-CM 272.9 (lipoid metabol dis NOS). The mapping is approximate, so confirm the match fits the documentation.
Does E75.6 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage: E75.6 maps to no category in the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 43 (Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders).
