2026 ICD-10-CM Diagnosis Code E72.10Disorders of sulfur-bearing amino-acid metabolism, unspecified

ICD-10-CM Codes›E00–E89›E70-E88›E72

ICD-10-CM E72.10
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E72.10 is a billable ICD-10-CM diagnosis code for disorders of sulfur-bearing amino-acid metabolism, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as deficiency of dihydrofolate reductase. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E72.10
Billable Status
Yes — Valid for Submission
Code Describes
Disorders of sulfur-bearing amino-acid metabolism, unspecified
Short Description
Disorders of sulfur-bearing amino-acid metabolism, unsp
Parent Code
E72.1
Disorders of sulfur-bearing amino-acid metabolism

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE72Other disorders of amino-acid metabolism
This CodeE72.10Disorders of sulfur-bearing amino-acid metabolism, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Deficiency of dihydrofolate reductase
  • Disorder of sulfur-bearing amino acid metabolism

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • metabolism NOS
        • amino-acid
          • sulfur-bearing
    • Disorder(of)
      • sulfur-bearing amino-acid metabolism
    • Disturbance(s)
      • metabolism
        • amino-acid
          • sulfur-bearing

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Amino Acid Metabolism Disorders

Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Your digestive system breaks the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E72.10 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
270.4 Sulph amino-acid met dis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E72.10Overview

Is E72.10 (Disorders of sulfur-bearing amino-acid metabolism) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report disorders of sulfur-bearing amino-acid metabolism, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of E72.10?

Under the General Equivalence Mappings, disorders of sulfur-bearing amino-acid metabolism, unspecified converts to ICD-9-CM 270.4 (sulph amino-acid met dis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.