2026 ICD-10-CM Diagnosis Code E34.1Other hypersecretion of intestinal hormones

ICD-10-CM Codes›E00–E89›E20-E35›E34

ICD-10-CM E34.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E34.1 is a billable ICD-10-CM diagnosis code for other hypersecretion of intestinal hormones. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. Coders also document this condition as non-pancreatic hypersecretion of intestinal hormones. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E34.1
Billable Status
Yes — Valid for Submission
Code Describes
Other hypersecretion of intestinal hormones
Short Description
Other hypersecretion of intestinal hormones
Same as the full description in the CMS dataset.
Parent Code
E34
Other endocrine disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE34Other endocrine disorders
This CodeE34.1Other hypersecretion of intestinal hormones

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Non-pancreatic hypersecretion of intestinal hormones

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Hypersecretion
      • hormone (s)
        • intestinal NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E34.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
259.8 Endocrine disorders NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E34.1Overview

Is E34.1 (Other endocrine disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other hypersecretion of intestinal hormones on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E34.1 group to?

When other hypersecretion of intestinal hormones is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E34.1?

Under the General Equivalence Mappings, other hypersecretion of intestinal hormones converts to ICD-9-CM 259.8 (endocrine disorders NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.