2027 ICD-10-CM Diagnosis Code E34.1Other hypersecretion of intestinal hormones

ICD-10-CM Codes›E00–E89›E20-E35›E34

ICD-10-CM E34.1
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E34.1 is a billable ICD-10-CM diagnosis code for other hypersecretion of intestinal hormones. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. Coders also document this condition as non-pancreatic hypersecretion of intestinal hormones. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E34.1
Billable Status
Yes — Valid for Submission
Code Describes
Other hypersecretion of intestinal hormones
Short Description
Other hypersecretion of intestinal hormones
Same as the full description in the CMS dataset.
Parent Code
E34
Other endocrine disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE20-E35Disorders of other endocrine glands
CategoryE34Other endocrine disorders
This CodeE34.1Other hypersecretion of intestinal hormones

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Non-pancreatic hypersecretion of intestinal hormones

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E34.1: its own notes plus those printed at E34, block E20-E35, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From E34 Other endocrine disorders applies to 18 codes
  • pseudohypoparathyroidism (E20.1)
From Block E20-E35 Disorders of other endocrine glands applies to 99 codes
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E34.1, its category, or a range that includes it.

Code First 1

These codes say to code first a condition named in the note, and E34.1 is one of the conditions named.

  • G63 Polyneuropathy in diseases classified elsewhere
    endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34) names E20-E34, which includes this code

Notes 1

These notes mention E34.1.

  • Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases
    All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere. names E34.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E34.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
259.8 Endocrine disorders NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E34.1Overview

What is the ICD-10 code for other hypersecretion of intestinal hormones?

The ICD-10-CM code for other hypersecretion of intestinal hormones is E34.1 (sometimes written as E341). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is E34.1 (Other endocrine disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other hypersecretion of intestinal hormones on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does E34.1 group to?

When other hypersecretion of intestinal hormones is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.

Can E34.1 be reported with E20.1?

Not as a rule. The Excludes1 note at E34, which applies to E34.1, lists "pseudohypoparathyroidism (E20.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of E34.1?

Under the General Equivalence Mappings, other hypersecretion of intestinal hormones converts to ICD-9-CM 259.8 (endocrine disorders NEC). The mapping is approximate, so confirm the match fits the documentation.