Valid for Submission
D81.89 is a billable diagnosis code used to specify a medical diagnosis of other combined immunodeficiencies. The code D81.89 is valid during the fiscal year 2022 from October 01, 2021 through September 30, 2022 for the submission of HIPAA-covered transactions.
The ICD-10-CM code D81.89 might also be used to specify conditions or terms like anhidrotic ectodermal dysplasia, immunodeficiency, osteopetrosis, lymphedema syndrome, combined immunodeficiency due to cd3gamma deficiency, combined immunodeficiency due to crac channel dysfunction, combined immunodeficiency due to interleukin 21 receptor deficiency, combined immunodeficiency due to malt1 deficiency , combined immunodeficiency due to ox40 deficiency, etc.
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D81.89 are found in the index:
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Anhidrotic ectodermal dysplasia, immunodeficiency, osteopetrosis, lymphedema syndrome
- Combined immunodeficiency due to CD3gamma deficiency
- Combined immunodeficiency due to CRAC channel dysfunction
- Combined immunodeficiency due to interleukin 21 receptor deficiency
- Combined immunodeficiency due to MALT1 deficiency
- Combined immunodeficiency due to OX40 deficiency
- Combined immunodeficiency due to STK4 deficiency
- Combined immunodeficiency due to ZAP70 deficiency
- Immunodeficiency by defective expression of human leukocyte antigen class 1
- Primary immunodeficiency with natural killer cell deficiency and adrenal insufficiency
- RIDDLE syndrome
- Severe combined immunodeficiency due to CARD11 deficiency
- Severe combined immunodeficiency due to DCLRE1C deficiency
- Severe combined immunodeficiency due to deoxyribonucleic acid dependent protein kinase catalytic subunit deficiency
- Severe combined immunodeficiency due to IKK2 deficiency
- Severe T-cell immunodeficiency, congenital alopecia, nail dystrophy syndrome
- Susceptibility to respiratory infection associated with CD8alpha chain mutation
- T-cell negative B-cell positive severe combined immunodeficiency due to JAK3 deficiency
- T-cell receptor alpha-beta-positive T-cell deficiency
- Warts, hypogammaglobulinemia, infections, and myelokathexis
- SEVERE COMBINED IMMUNODEFICIENCY-. group of rare congenital disorders characterized by impairment of both humoral and cell mediated immunity leukopenia and low or absent antibody levels. it is inherited as an x linked or autosomal recessive defect. mutations occurring in many different genes cause human severe combined immunodeficiency scid.
Diagnostic Related Groups - MS-DRG Mapping
|MS-DRG||MS-DRG Title||MCD||Relative Weight|
|808||MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH MCC||16||2.1779|
|809||MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITH CC||16||1.2217|
|810||MAJOR HEMATOLOGICAL AND IMMUNOLOGICAL DIAGNOSES EXCEPT SICKLE CELL CRISIS AND COAGULATION DISORDERS WITHOUT CC/MCC||16||0.9607|
The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.
Convert D81.89 to ICD-9 Code
The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code D81.89 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.
Information for Patients
Immune System and Disorders
What is the immune system?
Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases.
When germs such as bacteria or viruses invade your body, they attack and multiply. This is called an infection. The infection causes the disease that makes you sick. Your immune system protects you from the disease by fighting off the germs.
What are the parts of the immune system?
The immune system has many different parts, including
- Your skin, which can help prevent germs from getting into the body
- Mucous membranes, which are the moist, inner linings of some organs and body cavities. They make mucus and other substances which can trap and fight germs.
- White blood cells, which fight germs
- Organs and tissues of the lymph system, such as the thymus, spleen, tonsils, lymph nodes, lymph vessels, and bone marrow. They produce, store, and carry white blood cells.
How does the immune system work?
Your immune system defends your body against substances it sees as harmful or foreign. These substances are called antigens. They may be germs such as bacteria and viruses. They might be chemicals or toxins. They could also be cells that are damaged from things like cancer or sunburn.
When your immune system recognizes an antigen, it attacks it. This is called an immune response. Part of this response is to make antibodies. Antibodies are proteins that work to attack, weaken, and destroy antigens. Your body also makes other cells to fight the antigen.
Afterwards, your immune system remembers the antigen. If it sees the antigen again, it can recognize it. It will quickly send out the right antibodies, so in most cases, you don't get sick. This protection against a certain disease is called immunity.
What are the types of immunity?
There are three different types of immunity:
- Innate immunity is the protection that you are born with. It is your body's first line of defense. It includes barriers such as the skin and mucous membranes. They keep harmful substances from entering the body. It also includes some cells and chemicals which can attack foreign substances.
- Active immunity, also called adaptive immunity, develops when you are infected with or vaccinated against a foreign substance. Active immunity is usually long-lasting. For many diseases, it can last your entire life.
- Passive immunity happens when you receive antibodies to a disease instead of making them through your own immune system. For example, newborn babies have antibodies from their mothers. People can also get passive immunity through blood products that contain antibodies. This kind of immunity gives you protection right away. But it only lasts a few weeks or months.
What can go wrong with the immune system?
Sometimes a person may have an immune response even though there is no real threat. This can lead to problems such as allergies, asthma, and autoimmune diseases. If you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake.
Other immune system problems happen when your immune system does not work correctly. These problems include immunodeficiency diseases. If you have an immunodeficiency disease, you get sick more often. Your infections may last longer and can be more serious and harder to treat. They are often genetic disorders.
There are other diseases that can affect your immune system. For example, HIV is a virus that harms your immune system by destroying your white blood cells. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). People with AIDS have badly damaged immune systems. They get an increasing number of severe illnesses.
[Learn More in MedlinePlus]