Valid for Submission
D81.818 is a billable diagnosis code used to specify a medical diagnosis of other biotin-dependent carboxylase deficiency. The code D81.818 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions.
The ICD-10-CM code D81.818 might also be used to specify conditions or terms like biotinidase deficiency or holocarboxylase synthase deficiency.
Tabular List of Diseases and Injuries
The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D81.818:
Inclusion TermsInclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Holocarboxylase synthetase deficiency
- Other multiple carboxylase deficiency
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D81.818 are found in the index:
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Biotinidase deficiency
- Holocarboxylase synthase deficiency
Diagnostic Related Groups - MS-DRG Mapping
Convert D81.818 to ICD-9 Code
The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code D81.818 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.
Information for Patients
Immune System and Disorders
Your immune system is a complex network of cells, tissues, and organs that work together to defend against germs. It helps your body to recognize these "foreign" invaders. Then its job is to keep them out, or if it can't, to find and destroy them.
If your immune system cannot do its job, the results can be serious. Disorders of the immune system include
- Allergy and asthma - immune responses to substances that are usually not harmful
- Immune deficiency diseases - disorders in which the immune system is missing one or more of its parts
- Autoimmune diseases - diseases causing your immune system to attack your own body's cells and tissues by mistake
NIH: National Institute of Allergy and Infectious Diseases
- Agammaglobulinemia (Medical Encyclopedia)
- Aging changes in immunity (Medical Encyclopedia)
- Chronic granulomatous disease (Medical Encyclopedia)
- Graft-versus-host disease (Medical Encyclopedia)
- Histiocytosis (Medical Encyclopedia)
- Hyperimmunoglobulin E syndrome (Medical Encyclopedia)
- Immune response (Medical Encyclopedia)
- Immunodeficiency disorders (Medical Encyclopedia)
- Selective deficiency of IgA (Medical Encyclopedia)
[Learn More in MedlinePlus]
Holocarboxylase synthetase deficiency Holocarboxylase synthetase deficiency is an inherited disorder in which the body is unable to use the vitamin biotin effectively. This disorder is classified as a multiple carboxylase deficiency, which is a group of disorders characterized by impaired activity of certain enzymes that depend on biotin.The signs and symptoms of holocarboxylase synthetase deficiency typically appear within the first few months of life, but the age of onset varies. Affected infants often have difficulty feeding, breathing problems, a skin rash, hair loss (alopecia), and a lack of energy (lethargy). Immediate treatment and lifelong management with biotin supplements may prevent many of these complications. If left untreated, the disorder can lead to delayed development, seizures, and coma. These medical problems may be life-threatening in some cases.
[Learn More in MedlinePlus]