2026 ICD-10-CM Diagnosis Code D71.1Leukocyte adhesion deficiency

ICD-10-CM Codes›D50–D89›D70-D77›D71

ICD-10-CM D71.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D71.1 is a billable ICD-10-CM diagnosis code for leukocyte adhesion deficiency. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 808 through 810.

Code Identity

ICD-10-CM Code
D71.1
Billable Status
Yes — Valid for Submission
Code Describes
Leukocyte adhesion deficiency
Short Description
Leukocyte adhesion deficiency
Same as the full description in the CMS dataset.
Parent Code
D71
Functional disorders of polymorphonuclear neutrophils

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD71Functional disorders of polymorphonuclear neutrophils
This CodeD71.1Leukocyte adhesion deficiency

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • LAD-I
  • LAD-II
  • LAD-III
  • Leukocyte adhesion deficiency type I
  • Leukocyte adhesion deficiency type II
  • Leukocyte adhesion deficiency type III

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Deficiency, deficient
      • leukocyte adhesion (LAD-I) (LAD-II) (LAD-III)
    • Deficiency, deficient
      • leukocyte adhesion (LAD-I) (LAD-II) (LAD-III)
        • type I
    • Deficiency, deficient
      • leukocyte adhesion (LAD-I) (LAD-II) (LAD-III)
        • type II
    • Deficiency, deficient
      • leukocyte adhesion (LAD-I) (LAD-II) (LAD-III)
        • type III
    • LAD(leukocyte adhesion deficiency) (LAD-I) (LAD-II) (LAD-III)

Clinical InformationClinical

  • Leukocyte Adhesion Deficiency

    a rare autosomal recessive immunodeficiency disorder caused by deficiency of cd18 expression. it is characterized by defects in neutrophil adhesion and bacterial infections.

  • Leukocyte Adhesion Deficiency Type 1|LAD-1|LAD-1 Deficiency|LAD-Type I|LAD1|LFA-I Deficiency|LFA1 Immunodeficiency

    a rare immunodeficiency with an autosomal recessive pattern of inheritance. it is caused by mutation in the itgb2 gene on chromosome 21 which codes for the beta subunit of beta-2 integrin (cd18). the mutation results in significantly reduced or absent expression of cd18 on the surface of leukocytes which impairs their ability to migrate and interact with antigens. initial clinical signs include omphalitis and delayed separation of the umbilical cord. the clinical course is marked by recurrent bacterial and fungal infection without pus formation. in instances where there is < 1% expression of cd18, prognosis is dismal with a high likelihood for life-threatening infection within the first year of life.

  • Leukocyte Adhesion Deficiency Type 2|CDGIIc|Congenital Disorder of Glycosylation Type IIc|LAD-Type II|Sialyl-Lewis X Defect

    leukocyte adhesion deficiency, type ii. an inherited disease affecting the metabolism of fucose, which affects the expression of the sialyl lewis x antigen, the fucose-containing ligand for e- and p-selectins, resulting in a deficiency in neutrophil adhesion. syn sialyl-lewis x defect.

  • Leukocyte Adhesion Deficiency Type 3|LAD-3|LAD-III

    an autosomal recessive condition caused by mutation(s) in the fermt3 gene, encoding fermitin family homolog 3. it is characterized by a defect in activation of all beta integrins. it manifests clinically as severe infections with marked leukocytosis, accompanied by life-threatening bleeding episodes.

Code History & ChangesHistory

New Code D71.1 was added to the ICD-10-CM code set for FY 2026, effective October 1, 2025.

Replacement D71.1 replaces the following previously assigned code(s):

  • D71 - Functional disorders of polymorphonuclear neutrophils
FY 2026AddedAdded to the ICD-10-CM code setEffective October 1, 2025.
FY 2026CurrentRevised in the current code setEffective October 1, 2025 through September 30, 2026.

Questions About D71.1Overview

Is D71.1 (Functional disorders of polymorphonuclear neutrophils) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report leukocyte adhesion deficiency on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D71.1 group to?

When leukocyte adhesion deficiency is the principal diagnosis on an inpatient stay, it groups to MS-DRG 808, 809, 810, with relative weights from 1.0466 to 2.2079 depending on complications. Higher weights mean higher Medicare reimbursement.