2027 ICD-10-CM Diagnosis Code D71.1Leukocyte adhesion deficiency

ICD-10-CM Codes›D50–D89›D70-D77›D71

ICD-10-CM D71.1
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D71.1 is a billable ICD-10-CM diagnosis code for leukocyte adhesion deficiency. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 808 through 810. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Diseases of white blood cells.

For Medicare Advantage risk adjustment, D71.1 maps to CMS-HCC Category 115 (Specified Immunodeficiencies and White Blood Cell Disorders) under the V28 model, adding a risk factor of about 0.565 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
D71.1
Billable Status
Yes — Valid for Submission
Code Describes
Leukocyte adhesion deficiency
Short Description
Leukocyte adhesion deficiency
Same as the full description in the CMS dataset.
Parent Code
D71
Functional disorders of polymorphonuclear neutrophils

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD71Functional disorders of polymorphonuclear neutrophils
This CodeD71.1Leukocyte adhesion deficiency

Medicare Risk Adjustment (HCC)Billing

D71.1 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 115— Specified Immunodeficiencies and White Blood Cell Disorders
Payment HCC · PY 2027 one of 19 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.565
community, non-dual, aged · ranges 0.302–0.692 across segments
Hierarchy
Superseded by HCC 114
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
Not mapped under V24
this diagnosis newly risk-adjusts under the V28 model
Other CMS Models
PACE (CMS-HCC V22): HCC 47 · ESRD (V21): HCC 47 · ESRD (V24): HCC 47
ESRD V21 weights: 0.097 dialysis, 0.549–0.688 functioning graft · ESRD V24 weights: 0.078 dialysis, 0.523–0.803 functioning graft
Part D (RxHCC)
Not mapped
D71.1 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D71.1: its own notes plus those printed at Chapter 3. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • LAD-I
  • LAD-II
  • LAD-III
  • Leukocyte adhesion deficiency type I
  • Leukocyte adhesion deficiency type II
  • Leukocyte adhesion deficiency type III

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism applies to 324 codes
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D71.1, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming D71.1: they are not reported together with it, unless the two conditions are unrelated.

  • Block D80-D89 Certain disorders involving the immune mechanism
    functional disorders of polymorphonuclear neutrophils (D71-) names D71-, which includes this code

Excludes2 2

These codes carry an Excludes2 note naming D71.1: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block L20-L30 Dermatitis and eczema
    chronic (childhood) granulomatous disease (D71-) names D71-, which includes this code
  • Block R70-R79 Abnormal findings on examination of blood, without diagnosis
    abnormalities of white blood cells classified elsewhere (D70-D72) names D70-D72, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD007
Diseases of white blood cells
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Leukocyte Adhesion Deficiency

    a rare autosomal recessive immunodeficiency disorder caused by deficiency of cd18 expression. it is characterized by defects in neutrophil adhesion and bacterial infections.

Patient EducationClinical

Immune System and Disorders

Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases.

The full article covers:

  • What is the immune system?
  • What are the parts of the immune system?
  • How does the immune system work?
  • What are the types of immunity?
  • What can go wrong with the immune system?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement D71.1 replaces the following previously assigned code(s):

  • D71 - Functional disorders of polymorphonuclear neutrophils
FY 2026AddedAdded to the ICD-10-CM code setEffective October 1, 2025.
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D71.1Overview

What is the ICD-10 code for leukocyte adhesion deficiency?

The ICD-10-CM code for leukocyte adhesion deficiency is D71.1 (sometimes written as D711). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D71.1 (Functional disorders of polymorphonuclear neutrophils) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report leukocyte adhesion deficiency on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D71.1 group to?

When leukocyte adhesion deficiency is the principal diagnosis on an inpatient stay, it groups to MS-DRG 808, 809, 810, with relative weights from 1.0749 to 2.1706 depending on complications. Higher weights mean higher Medicare reimbursement.

What HCC is D71.1?

D71.1 (leukocyte adhesion deficiency) maps to CMS-HCC Category 115 (Specified Immunodeficiencies and White Blood Cell Disorders), commonly written as HCC 115, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.

Does D71.1 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, D71.1 adds a risk adjustment factor of about 0.565 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.302 to 0.692 depending on the payment segment). A more severe related category (HCC 114) supersedes it when both are reported. See the full factor table on the HCC 115 category page.