Other and unspecified diseases of blood and blood-forming organs (D75) ICD-10-CM
The D75 code range covers other and unspecified diseases of blood and blood-forming organs with 17 ICD-10-CM diagnosis codes. 13 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Codes in the D75 Range 17 codes · 13 billable
- D75 Other and unspecified diseases of blood and blood-forming organsNon-billable
- D75.0 Familial erythrocytosis
- D75.1 Secondary polycythemia
- D75.8 Other specified diseases of blood and blood-forming organsNon-billable
- D75.81 Myelofibrosis
- D75.82 Heparin induced thrombocytopenia (HIT)Non-billable
- D75.821 Non-immune heparin-induced thrombocytopenia
- D75.822 Immune-mediated heparin-induced thrombocytopenia
- D75.828 Other heparin-induced thrombocytopenia syndrome
- D75.829 Heparin-induced thrombocytopenia, unspecified
- D75.83 ThrombocytosisNon-billable
- D75.838 Other thrombocytosis
- D75.839 Thrombocytosis, unspecified
- D75.84 Other platelet-activating anti-PF4 disorders
- D75.89 Other specified diseases of blood and blood-forming organs
- D75.9 Disease of blood and blood-forming organs, unspecified
- D75.A Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the D75 range.
Acute Radiation Syndrome
A condition caused by a brief whole body exposure to more than one sievert dose equivalent of radiation. Acute radiation syndrome is initially characterized by ANOREXIA; NAUSEA; VOMITING; but can progress to hematological, gastrointestinal, neurological, pulmonary, and other major organ dysfunction.
Carotid Artery, Common
The two principal arteries supplying the structures of the head and neck. They ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (CAROTID ARTERY, EXTERNAL) and internal (CAROTID ARTERY, INTERNAL) carotid arteries.
Carotid Body Tumor
Benign paraganglioma at the bifurcation of the COMMON CAROTID ARTERIES. It can encroach on the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies.
Cytopenia
A deficiency in or reduction of the number of blood cells.
Glomus Jugulare Tumor
A paraganglioma involving the glomus jugulare, a microscopic collection of chemoreceptor tissue in the adventitia of the bulb of the jugular vein. It may cause paralysis of the vocal cords, attacks of dizziness, blackouts, and nystagmus. It is not resectable but radiation therapy is effective. It regresses slowly, but permanent control is regularly achieved. (From Dorland, 27th ed; Stedman, 25th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1603-4)
Paraganglioma
A neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). It is more common in women than in men. (Stedman, 25th ed; from Segen, Dictionary of Modern Medicine, 1992)
Paraganglioma, Extra-Adrenal
A relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the CAROTID BODY; GLOMUS JUGULARE; GLOMUS TYMPANICUM; AORTIC BODIES; and the female genital tract. It consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. (From Stedman, 27th ed)
Polycythemia Vera
A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
Pseudolymphoma
A group of disorders having a benign course but exhibiting clinical and histological features suggestive of malignant lymphoma. Pseudolymphoma is characterized by a benign infiltration of lymphoid cells or histiocytes which microscopically resembles a malignant lymphoma. (From Dorland, 28th ed & Stedman, 26th ed)
Thrombocythemia, Essential
A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.
Thrombocytosis
Increased numbers of platelets in the peripheral blood. (Dorland, 27th ed)
About the D75 Code Range
The ICD-10 code section D75 covers various other and unspecified diseases of the blood and blood-forming organs beyond common blood disorders. These codes are essential for classifying rare, familial, or less clearly defined hematologic conditions to ensure accurate diagnosis and treatment documentation.
This section includes codes like D75.0 for familial erythrocytosis, also known as polycythemia vera clinically or primary familial polycythemia caused by erythropoietin receptor mutations. D75.1 captures secondary polycythemia, which relates to increased red blood cells from various causes including heart or lung disease, high altitude, or tumors. D75.81 refers to myelofibrosis, a bone marrow disorder that replaces marrow with fibrous tissue, and D75.82 addresses heparin-induced thrombocytopenia (HIT), a serious complication of heparin therapy. Several other codes classify thrombocytosis (high platelet counts), other platelet-activating disorders, and glucose-6-phosphate dehydrogenase deficiency without anemia (D75.A). The unspecified code D75.9 applies when precise diagnoses are unclear but involve blood or marrow abnormalities. These specific ICD-10 codes assist healthcare professionals and coders in accurately capturing a broad array of complex hematologic conditions that require specialized management.
Questions About This Page
How many billable codes are in the D75 range?
Of the 17 codes in this range, 13 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the D75 range classify?
The range classifies other and unspecified diseases of blood and blood-forming organs. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
