Neutropenia (D70)

Neutropenia, classified under ICD-10 code D70, is a condition characterized by abnormally low levels of neutrophils, a type of white blood cell essential for fighting infections. These codes are used to identify various types of neutropenia, ranging from congenital forms to those caused by drugs, infections, or other medical conditions.

The ICD-10 code D70.0 specifies congenital agranulocytosis, known by several synonyms like Kostmann syndrome and congenital neutropenia. Code D70.1 covers neutropenia resulting from cancer chemotherapy, while D70.2 describes neutropenia induced by other drugs. Infection-related neutropenia is captured by D70.3. Cyclic neutropenia, marked by periodic drops in neutrophil counts, has its own code D70.4. D70.8 includes other forms such as autoimmune or benign ethnic neutropenia, often linked to disorders like febrile neutropenia or immune neutropenia. Lastly, D70.9 denotes unspecified neutropenia, useful when the exact cause is unknown. Understanding these codes helps healthcare providers and medical coders accurately document and manage patients with various neutropenia conditions using the appropriate ICD-10 code for neutropenia.

Instructional Notations

Includes

This note appears immediately under a three character code title to further define, or give examples of, the content of the category.

  • agranulocytosis
  • decreased absolute neurophile count (ANC)

Code Also

A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.

Use Additional Code

The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.

  • code for any associated:
  • fever R50.81

Type 1 Excludes

A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

  • neutropenic splenomegaly D73.81
  • transient neonatal neutropenia P61.5

Clinical Terms

The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.

Agranulocytosis

A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Chemotherapy-Induced Febrile Neutropenia

FEVER accompanied by a significant reduction in NEUTROPHIL count associated with CHEMOTHERAPY.

Febrile Neutropenia

Fever accompanied by a significant reduction in the number of NEUTROPHILS.

Feline Panleukopenia

A highly contagious DNA virus infection of the cat family, characterized by fever, enteritis and bone marrow changes. It is also called feline ataxia, feline agranulocytosis, feline infectious enteritis, cat fever, cat plague, and show fever. It is caused by FELINE PANLEUKOPENIA VIRUS or the closely related MINK ENTERITIS VIRUS or CANINE PARVOVIRUS.

Neutropenia

A decrease in the number of NEUTROPHILS found in the blood.

Neutrophils

Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.