2027 ICD-10-CM Diagnosis Code D37.8Neoplasm of uncertain behavior of other specified digestive organs
ICD-10-CM Codes›C00–D49›D37-D48›D37
- Billable — Valid for Submission
- Not Chronic
D37.8 is a billable ICD-10-CM diagnosis code for neoplasm of uncertain behavior of other specified digestive organs. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 374 through 376. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Diffuse leiomyomatosis of esophagus
- Glucagonoma syndrome
- Hemangioblastoma of intestine
- Hemangioblastoma of pancreas
- Necrolytic migratory erythema
- Neoplasm of body of pancreas
- Neoplasm of head of pancreas
- Neoplasm of tail of pancreas
- Neoplasm of uncertain behavior of abdominal esophagus
- Neoplasm of uncertain behavior of anal canal
- Neoplasm of uncertain behavior of anal canal and sphincter
- Neoplasm of uncertain behavior of anus
- Neoplasm of uncertain behavior of body of pancreas
- Neoplasm of uncertain behavior of cervical esophagus
- Neoplasm of uncertain behavior of esophagus
- Neoplasm of uncertain behavior of head of pancreas
- Neoplasm of uncertain behavior of intestinal tract
- Neoplasm of uncertain behavior of islets of Langerhans
- Neoplasm of uncertain behavior of lower third of esophagus
- Neoplasm of uncertain behavior of middle third of esophagus
- Neoplasm of uncertain behavior of pancreas
- Neoplasm of uncertain behavior of pancreatic duct
- Neoplasm of uncertain behavior of soft tissues of perineum
- Neoplasm of uncertain behavior of spleen
- Neoplasm of uncertain behavior of tail of pancreas
- Neoplasm of uncertain behavior of thoracic esophagus
- Neoplasm of uncertain behavior of upper third of esophagus
- Somatostatinoma
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to D37.8: its own notes plus those printed at D37, block D37-D48, and Chapter 2. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Neoplasm of uncertain behavior of anal canal
- Neoplasm of uncertain behavior of anal sphincter
- Neoplasm of uncertain behavior of anus NOS
- Neoplasm of uncertain behavior of esophagus
- Neoplasm of uncertain behavior of intestine NOS
- Neoplasm of uncertain behavior of pancreas
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- stromal tumors of uncertain behavior of digestive system (D48.1-)
- neoplasms of unspecified behavior (D49.-)
Notes
General instructions on how these codes are used.
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name D37.8, its category, or a range that includes it.
Excludes1 2
These codes carry an Excludes1 note naming D37.8: they are not reported together with it, unless the two conditions are unrelated.
Excludes2 1
These codes carry an Excludes2 note naming D37.8: its condition is not part of those codes, and both may be reported when the patient has both.
- D49 Neoplasms of unspecified behavior
Notes 1
These notes mention D37.8.
- Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Tumor See Also: Neoplasm, unspecified behavior, by site;
unspecified site D37.8
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Table of NeoplasmsClinical
Anatomical sites in the Table of Neoplasms that reference this code family.
| Site | Malig. Primary | Malig. Secondary | Ca in situ | Benign | Uncertain | Unspec. |
|---|---|---|---|---|---|---|
| anorectum, anorectal (junction) | C21.8 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| anus, anal | C21.0 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| anus, anal › canal | C21.1 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| anus, anal › cloacogenic zone | C21.2 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| anus, anal › sphincter | C21.1 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| canal › anal | C21.1 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| cloacogenic zone | C21.2 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| crypt of Morgagni | C21.8 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| esophagus | C15.9 | C78.89 | D00.1 | D13.0 | D37.8 | D49.0 |
| esophagus › abdominal | C15.5 | C78.89 | D00.1 | D13.0 | D37.8 | D49.0 |
| esophagus › cervical | C15.3 | C78.89 | D00.1 | D13.0 | D37.8 | D49.0 |
| esophagus › distal (third) | C15.5 | C78.89 | D00.1 | D13.0 | D37.8 | D49.0 |
| esophagus › lower (third) | C15.5 | C78.89 | D00.1 | D13.0 | D37.8 | D49.0 |
| esophagus › middle (third) | C15.4 | C78.89 | D00.1 | D13.0 | D37.8 | D49.0 |
| esophagus › proximal (third) | C15.3 | C78.89 | D00.1 | D13.0 | D37.8 | D49.0 |
| esophagus › thoracic | C15.4 | C78.89 | D00.1 | D13.0 | D37.8 | D49.0 |
| esophagus › upper (third) | C15.3 | C78.89 | D00.1 | D13.0 | D37.8 | D49.0 |
| hemorrhoidal zone | C21.1 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| insular tissue (pancreas) | C25.4 | C78.89 | D01.7 | D13.7 | D37.8 | D49.0 |
| intestine, intestinal | C26.0 | C78.80 | D01.40 | D13.99 | D37.8 | D49.0 |
| intestine, intestinal › tract NEC | C26.0 | C78.89 | D01.40 | D13.99 | D37.8 | D49.0 |
| islands or islets of Langerhans | C25.4 | C78.89 | D01.7 | D13.7 | D37.8 | D49.0 |
| junction › anorectal | C21.8 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| Langerhans, islands or islets | C25.4 | C78.89 | D01.7 | D13.7 | D37.8 | D49.0 |
| pancreas | C25.9 | C78.89 | D01.7 | D13.6 | D37.8 | D49.0 |
| pancreas › body | C25.1 | C78.89 | D01.7 | D13.6 | D37.8 | D49.0 |
| pancreas › duct (of Santorini) (of Wirsung) | C25.3 | C78.89 | D01.7 | D13.6 | D37.8 | D49.0 |
| pancreas › ectopic tissue | C25.7 | C78.89 | – | D13.6 | D37.8 | D49.0 |
| pancreas › head | C25.0 | C78.89 | D01.7 | D13.6 | D37.8 | D49.0 |
| pancreas › islet cells | C25.4 | C78.89 | D01.7 | D13.7 | D37.8 | D49.0 |
| pancreas › neck | C25.7 | C78.89 | D01.7 | D13.6 | D37.8 | D49.0 |
| pancreas › tail | C25.2 | C78.89 | D01.7 | D13.6 | D37.8 | D49.0 |
| Santorini's duct | C25.3 | C78.89 | D01.7 | D13.6 | D37.8 | D49.0 |
| sphincter › anal | C21.1 | C78.5 | D01.3 | D12.9 | D37.8 | D49.0 |
| spleen, splenic NEC | C26.1 | C78.89 | D01.7 | D13.99 | D37.8 | D49.0 |
| Wirsung's duct | C25.3 | C78.89 | D01.7 | D13.6 | D37.8 | D49.0 |
Patient EducationClinical
Digestive Diseases
When you eat, your body breaks food down to a form it can use to build and nourish cells and provide energy. This process is called digestion.
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Convert D37.8 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D37.8Overview
What is the ICD-10 code for neoplasm of uncertain behavior of other specified digestive organs?
The ICD-10-CM code for neoplasm of uncertain behavior of other specified digestive organs is D37.8 (sometimes written as D378). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is D37.8 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report neoplasm of uncertain behavior of other specified digestive organs on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does D37.8 group to?
When neoplasm of uncertain behavior of other specified digestive organs is the principal diagnosis on an inpatient stay, it groups to MS-DRG 375, 374, 376, with relative weights from 0.8925 to 2.1101 depending on complications. Higher weights mean higher Medicare reimbursement.
Can D37.8 be reported with D48.5?
Not as a rule. The Excludes1 note on D37.8 lists "neoplasm of uncertain behavior of anal margin (D48.5)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of D37.8?
Under the General Equivalence Mappings, neoplasm of uncertain behavior of other specified digestive organs converts to ICD-9-CM 235.5 (unc behav neo GI NEC). The mapping is approximate, so confirm the match fits the documentation.
