2021 ICD-10-CM Code C78.5

Secondary malignant neoplasm of large intestine and rectum

Version 2021

Valid for Submission

ICD-10:C78.5
Short Description:Secondary malignant neoplasm of large intestine and rectum
Long Description:Secondary malignant neoplasm of large intestine and rectum

Code Classification

  • Neoplasms (C00–D48)
    • Malignant neoplasms of ill-defined, other secondary and unspecified sites (C76-C80)
      • Secondary malignant neoplasm of resp and digestive organs (C78)

C78.5 is a billable diagnosis code used to specify a medical diagnosis of secondary malignant neoplasm of large intestine and rectum. The code C78.5 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions.

The ICD-10-CM code C78.5 might also be used to specify conditions or terms like malignant neoplasm of rectum, rectosigmoid junction and anus, malignant tumor involving rectum by direct extension from endometrium, malignant tumor involving rectum by direct extension from fallopian tube, malignant tumor involving rectum by direct extension from ovary, malignant tumor involving rectum by direct extension from prostate , malignant tumor involving rectum by direct extension from uterine cervix, etc.

The following anatomical sites found in the Table of Neoplasms apply to this code given the correct histological behavior: Neoplasm, neoplastic anorectum, anorectal (junction) ; Neoplasm, neoplastic anus, anal ; Neoplasm, neoplastic anus, anal canal ; Neoplasm, neoplastic anus, anal cloacogenic zone ; Neoplasm, neoplastic anus, anal sphincter ; Neoplasm, neoplastic appendix ; Neoplasm, neoplastic canal ; etc

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

Convert C78.5 to ICD-9 Code

Table of Neoplasms

The code C78.5 is included in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»Neoplasm, neoplastic
  »anorectum, anorectal (junction)
C21.8C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »anus, anal
C21.0C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »anus, anal
    »canal
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »anus, anal
    »cloacogenic zone
C21.2C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »anus, anal
    »sphincter
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »appendix
C18.1C78.5D01.0D12.1D37.3D49.0
»Neoplasm, neoplastic
  »canal
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »canal
    »anal
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »caput coli
C18.0C78.5D01.0D12.0D37.4D49.0
»Neoplasm, neoplastic
  »cecum
C18.0C78.5D01.0D12.0D37.4D49.0
»Neoplasm, neoplastic
  »cloacogenic zone
C21.2C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »colon [See Also: Neoplasm, intestine, large]
C18.9C78.5
»Neoplasm, neoplastic
  »colon [See Also: Neoplasm, intestine, large]
    »with rectum
C19C78.5D01.1D12.7D37.5D49.0
»Neoplasm, neoplastic
  »crypt of Morgagni
C21.8C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »hemorrhoidal zone
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »hepatic [See Also: Index to disease, by histology]
    »flexure (colon)
C18.3C78.5D01.0D12.3D37.4D49.0
»Neoplasm, neoplastic
  »ileocecum, ileocecal (coil) (junction) (valve)
C18.0C78.5D01.0D12.0D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
C18.9C78.5D01.0D12.6D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »appendix
C18.1C78.5D01.0D12.1D37.3D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »caput coli
C18.0C78.5D01.0D12.0D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »cecum
C18.0C78.5D01.0D12.0D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
C18.9C78.5D01.0D12.6D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »and rectum
C19C78.5D01.1D12.7D37.5D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »ascending
C18.2C78.5D01.0D12.2D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »caput
C18.0C78.5D01.0D12.0D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »descending
C18.6C78.5D01.0D12.4D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »distal
C18.6C78.5D01.0D12.4D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »left
C18.6C78.5D01.0D12.4D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »pelvic
C18.7C78.5D01.0D12.5D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »right
C18.2C78.5D01.0D12.2D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »sigmoid (flexure)
C18.7C78.5D01.0D12.5D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »colon
        »transverse
C18.4C78.5D01.0D12.3D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »hepatic flexure
C18.3C78.5D01.0D12.3D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »ileocecum, ileocecal (coil) (valve)
C18.0C78.5D01.0D12.0D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »sigmoid flexure (lower) (upper)
C18.7C78.5D01.0D12.5D37.4D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »large
      »splenic flexure
C18.5C78.5D01.0D12.3D37.4D49.0
»Neoplasm, neoplastic
  »junction
C21.8C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »junction
    »anorectal
C21.8C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »junction
    »ileocecal
C18.0C78.5D01.0D12.0D37.4D49.0
»Neoplasm, neoplastic
  »junction
    »pelvirectal
C19C78.5D01.1D12.7D37.5D49.0
»Neoplasm, neoplastic
  »junction
    »rectosigmoid
C19C78.5D01.1D12.7D37.5D49.0
»Neoplasm, neoplastic
  »pelvirectal junction
C19C78.5D01.1D12.7D37.5D49.0
»Neoplasm, neoplastic
  »rectosigmoid (junction)
C19C78.5D01.1D12.7D37.5D49.0
»Neoplasm, neoplastic
  »rectum (ampulla)
C20C78.5D01.2D12.8D37.5D49.0
»Neoplasm, neoplastic
  »rectum (ampulla)
    »and colon
C19C78.5D01.1D12.7D37.5D49.0
»Neoplasm, neoplastic
  »sigmoid flexure (lower) (upper)
C18.7C78.5D01.0D12.5D37.4D49.0
»Neoplasm, neoplastic
  »sphincter
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »sphincter
    »anal
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »spleen, splenic NEC
    »flexure (colon)
C18.5C78.5D01.0D12.3D37.4D49.0

Information for Patients


Colorectal Cancer

Also called: Colon cancer, Rectal cancer

The colon and rectum are part of the large intestine. Colorectal cancer occurs when tumors form in the lining of the large intestine. It is common in both men and women. The risk of developing colorectal cancer rises after age 50. You're also more likely to get it if you have colorectal polyps, a family history of colorectal cancer, ulcerative colitis or Crohn's disease, eat a diet high in fat, or smoke.

Symptoms of colorectal cancer include

Because you may not have symptoms at first, it's important to have screening tests. Everyone over 50 should get screened. Tests include colonoscopy and tests for blood in the stool. Treatments for colorectal cancer include surgery, chemotherapy, radiation, or a combination. Surgery can usually cure it when it is found early.

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)