Other nontoxic goiter (E04) ICD-10-CM
The E04 code range covers other nontoxic goiter with 6 ICD-10-CM diagnosis codes. 5 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Codes in the E04 Range 6 codes · 5 billable
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the E04 range.
Goiter
Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
Goiter, Endemic
A form of IODINE deficiency disorders characterized by an enlargement of the THYROID GLAND in a significantly large fraction of a POPULATION GROUP. Endemic goiter is common in mountainous and iodine-deficient areas of the world where the DIET contains insufficient amount of iodine.
Goiter, Nodular
An enlarged THYROID GLAND containing multiple nodules (THYROID NODULE), usually resulting from recurrent thyroid HYPERPLASIA and involution over many years to produce the irregular enlargement. Multinodular goiters may be nontoxic or may induce THYROTOXICOSIS.
Goiter, Substernal
An enlarged THYROID GLAND with at least 50% of the gland situated behind the STERNUM. It is an unusual presentation of an intrathoracic goiter. Substernal goiters frequently cause compression on the TRACHEA leading to deviation, narrowing, and respiratory symptoms.
Graves Disease
A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
Lingual Goiter
Pathological enlargement of the LINGUAL THYROID, ectopic thyroid tissue at the base of the TONGUE. It may cause upper AIRWAY OBSTRUCTION; DYSPHAGIA; or HYPOTHYROIDISM symptoms.
Thyroid Nodule
A small circumscribed mass in the THYROID GLAND that can be of neoplastic growth or non-neoplastic abnormality. It lacks a well-defined capsule or glandular architecture. Thyroid nodules are often benign but can be malignant. The growth of nodules can lead to a multinodular goiter (GOITER, NODULAR).
About the E04 Code Range
This section covers the ICD-10 codes for other nontoxic goiter, which are thyroid gland enlargements not caused by hormone overproduction. These codes help specify different types and presentations of nontoxic goiters.
The ICD-10 code for other nontoxic goiter (E04) includes detailed subcodes to distinguish between forms like nontoxic diffuse goiter (E04.0), also known as simple or colloid goiter, and nontoxic single thyroid nodule (E04.1), which covers benign thyroid lumps such as hyperplastic or uninodular goiter. For multiple nodules, nontoxic multinodular goiter (E04.2) captures conditions like familial multinodular goiter syndrome. The code E04.8 is used for other specified nontoxic goiters, including thyroid adenomas or degenerative changes. If the nontoxic goiter type is unknown, E04.9 applies, covering unspecified thyroid masses or goiters such as substernal or sporadic goiters. These codes assist medical coders in accurately documenting and differentiating goiter types when thyroid hormone levels remain normal, ensuring precise coding for diagnosis and treatment.
Questions About This Page
How many billable codes are in the E04 range?
Of the 6 codes in this range, 5 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the E04 range classify?
The range classifies other nontoxic goiter. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
