Niacin deficiency [pellagra] (E52) ICD-10-CM
The E52 code range covers niacin deficiency [pellagra] with 1 ICD-10-CM diagnosis codes. 1 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Niacin (-tryptophan) deficiency
- Nicotinamide deficiency
- Pellagra (alcoholic)
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- sequelae of niacin deficiency E64.8
Codes in the E52 Range 1 codes · 1 billable
- E52 Niacin deficiency [pellagra]
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the E52 range.
Pellagra
A disease due to deficiency of NIACIN, a B-complex vitamin, or its precursor TRYPTOPHAN. It is characterized by scaly DERMATITIS which is often associated with DIARRHEA and DEMENTIA (the three D's).
About the E52 Code Range
ICD-10 code E52 is used to identify cases of niacin deficiency, commonly known as pellagra, a nutritional condition caused by insufficient niacin intake. This code specifically covers the clinical issues arising from a lack of niacin, which is essential for proper metabolism and nervous system function.
Niacin deficiency [pellagra] includes various presentations such as dementia and polyneuropathy linked to inadequate niacin levels. It relates to conditions often described as dementia due to niacin deficiency or pellagra neuropathy, and may be triggered by factors like poor diet, alcoholism (referred to as alcoholic pellagra), or drug-induced causes. This ICD-10 code helps distinguish these manifestations from other nutritional deficiencies. Medical coders looking for the ICD-10 code for pellagra or its synonyms will use E52 to ensure accurate classification of niacin deficiency-related disorders for patient records and treatment planning.
Questions About This Page
How many billable codes are in the E52 range?
Of the 1 codes in this range, 1 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the E52 range classify?
The range classifies niacin deficiency [pellagra]. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
