2027 ICD-10-CM Diagnosis Code T45.0X3APoisoning by antiallergic and antiemetic drugs, assault, initial encounter

ICD-10-CM Codes›S00–T88›T36-T50›T45

ICD-10-CM T45.0X3A
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T45.0X3A is a billable ICD-10-CM diagnosis code for poisoning by antiallergic and antiemetic drugs, assault, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, assault; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

Code Identity

ICD-10-CM Code
T45.0X3A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by antiallergic and antiemetic drugs, assault, initial encounter
Short Description
Poisoning by antiallerg/antiemetic, assault, init
Parent Code
Poisoning by antiallergic and antiemetic drugs, assault

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT45Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified
This CodeT45.0X3APoisoning by antiallergic and antiemetic drugs, assault, initial encounter

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified (T45). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T45.0X3A: its own notes plus those printed at T45.0, T45, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From T45.0 Poisoning by, adverse effect of and underdosing of antiallergic and antiemetic drugs applies to 18 codes
  • poisoning by, adverse effect of and underdosing of phenothiazine-based neuroleptics (T43.3)
From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T45 Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified applies to 270 codes
  • The appropriate 7th character is to be added to each code from category T45
  • Ainitial encounter this code
  • Dsubsequent encounter
  • Ssequela

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT022
External cause codes: intent of injury, assault
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AcrivastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AlizaprideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antazolin (e)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antiallergic NECT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antiemetic drugT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AntihistamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antinausea drugT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AntistineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antivertigo drugT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AstemizoleT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AzatadineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AzelastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BamipineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BenadrylT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Benzhydramine (chloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BenzquinamideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Bisulepin (hydrochloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BonineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BromazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BromodiphenhydramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BrompheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BuclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CarbinoxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Cerium oxalateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Cerous oxalateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CetirizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CetoximeT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorcyclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChloropyramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChloropyrileneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorothenT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorphenamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorpheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorphenoxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Chlor-TrimetonT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CinnarizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ClemastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ClemizoleT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ClorfenamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CyclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CyproheptadineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DeptropineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DexbrompheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DexchlorpheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DibenzheptropineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DifenidolT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimenhydrinateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimetaneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimethindeneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimetindeneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DiphenhydramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DiphenidolT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DiphenylpyralineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DomperidoneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DoxylamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DramamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
EmbramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
GranisetronT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
HomochlorcyclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Hydroxyzine::antiallergicT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
IsothipendylT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
KetotifenT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Levocabastine (hydrochloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
LoratidineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Magnesium NEC::thiosulfateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MarezineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MebhydrolinT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Meclizine (hydrochloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MeclozineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MephenhydramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MepyramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MethaphenileneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MethapyrileneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MetoclopramideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MoxastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
NytolT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
OndansetronT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
OxatomideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Percogesic [See Also: acetaminophen]T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PeriactinT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PhenindamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PhenyltoloxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PimethixeneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PipamazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PipoxizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PiprinhydrinateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PropiomazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyrathiazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyribenzamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyrilamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyrrobutamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
RotoxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
SetastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Sleep-ezeT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
SominexT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TerfenadineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ThenyldiamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Thonzylamine (systemic)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TiganT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TranilastT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TrimethobenzamideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TrimetonT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TripelennamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TriprolidineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TritoqualineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T45.0X3A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
963.0 Pois-antiallrg/antiemet
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E962.0 Assault-pois w medic agt
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T45.0X3AOverview

Is T45.0X3A (Poisoning by antiallergic and antiemetic drugs, assault) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by antiallergic and antiemetic drugs, assault, initial encounter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character A in T45.0X3A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by antiallergic and antiemetic drugs, assault, such as an emergency visit or first evaluation.

What MS-DRG does T45.0X3A group to?

When poisoning by antiallergic and antiemetic drugs, assault, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 918, 917, with relative weights from 0.8716 to 1.5698 depending on complications. Higher weights mean higher Medicare reimbursement.

Can T45.0X3A be reported with T43.3?

Not as a rule. The Excludes1 note at T45.0, which applies to T45.0X3A, lists "poisoning by, adverse effect of and underdosing of phenothiazine-based neuroleptics (T43.3)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of T45.0X3A?

Under the General Equivalence Mappings, poisoning by antiallergic and antiemetic drugs, assault, initial encounter converts to ICD-9-CM 963.0 (pois-antiallrg/antiemet) and E962.0 (assault-pois w medic agt). The mapping is approximate, so confirm the match fits the documentation.