Toxic effects of substances chiefly nonmedicinal as to source (T51-T65) ICD-10-CM
The T51–T65 section covers toxic effects of substances chiefly nonmedicinal as to source with 2,406 ICD-10-CM diagnosis codes, of which 1,632 are billable in fiscal year 2026. The section is organized into the 15 code ranges listed below.
Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
- code(s):
- for all associated manifestations of toxic effect, such as: respiratory conditions due to external agents J60 J70
- personal history of foreign body fully removed Z87.821
- to identify any retained foreign body, if applicable Z18
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- contact with and suspected exposure to toxic substances Z77
- When no intent is indicated code to accidental. Undetermined intent is only for use when there is specific documentation in the record that the intent of the toxic effect cannot be determined.
Code Ranges in This Section 15 ranges · 2,406 codes
The info icon previews the code ranges inside each row and its instructional notations from the official Tabular List.
About the T51–T65 Code Range
ICD-10 codes T51-T65 cover toxic effects caused by nonmedicinal substances originating from various sources, including alcohols, organic solvents, metals, pesticides, seafood toxins, and venomous animals or plants. These codes help specify the type of toxic substance involved and the context, such as accidental poisoning, intentional self-harm, assault, or undetermined causes.
This range includes detailed classifications like T51 codes for toxic effects of different alcohols, addressing toxicities from ethanol and methanol with synonyms like "adverse reaction to ethanol" or "accidental poisoning by methyl alcohol." The T52 series concerns toxic effects of organic solvents, including petroleum products and benzene derivatives, with attention to accidental or intentional exposures. Metal toxicities are captured under T56, for example, lead, mercury, and cadmium poisoning, with terms like "lead neuropathy" and "toxic encephalopathy caused by mercury." Codes from T60 cover toxic effects from pesticides with substances such as organophosphates and carbamates, identified by synonyms like "poisoning by anticholinesterase." The T61 section relates to toxic effects of seafood toxins, like ciguatera and scombroid fish poisoning. Codes from T63 specify toxic effects from venomous animal and plant contact, including snake venom and insect stings, addressing different intent and clinical situations. Each code also captures encounter context and potential sequela, providing comprehensive classification for medical coders and health professionals to accurately document poisoning incidents involving nonmedicinal substances.
Questions About This Page
How many codes are in the T51-T65 range?
The T51-T65 range contains 2,406 ICD-10-CM diagnosis codes in FY 2026. 1,632 of them are billable, and the rest are category headers that organize the section.
What conditions does T51-T65 cover?
The range covers toxic effects of substances chiefly nonmedicinal as to source. The code ranges listed above break it into groups of related conditions, and each one links to its own page with the full code list.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
