ICD-10-CM Code T45.1X2A

Poisoning by antineoplastic and immunosuppressive drugs, intentional self-harm, initial encounter

Version 2020 Replaced Code Billable Code

Valid for Submission

T45.1X2A is a billable code used to specify a medical diagnosis of poisoning by antineoplastic and immunosuppressive drugs, intentional self-harm, initial encounter. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code T45.1X2A might also be used to specify conditions or terms like aclarubicin overdose, aclarubicin poisoning, aminoglutethimide overdose, aminoglutethimide poisoning, amsacrine overdose, amsacrine poisoning, etc

Short Description:Poisoning by antineopl and immunosup drugs, self-harm, init
Long Description:Poisoning by antineoplastic and immunosuppressive drugs, intentional self-harm, initial encounter

Replaced Code

This code was replaced in the 2020 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2019. This code was replaced for the FY 2020 (October 1, 2019 - September 30, 2020).

  • K59.03 - Drug induced constipation


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Aclarubicin overdose
  • Aclarubicin poisoning
  • Aminoglutethimide overdose
  • Aminoglutethimide poisoning
  • Amsacrine overdose
  • Amsacrine poisoning
  • Azathioprine overdose
  • Bleomycin overdose
  • Busulfan overdose
  • Calcineurin inhibitor poisoning
  • Carboplatin overdose
  • Carboplatin poisoning
  • Carmustine overdose
  • Carmustine poisoning
  • Chlorambucil overdose
  • Chlormethine overdose
  • Chlormethine poisoning
  • Cisplatin overdose
  • Cisplatin poisoning
  • Crisantaspase overdose
  • Crisantaspase poisoning
  • Cyclophosphamide overdose
  • Cyclosporin overdose
  • Cyclosporin poisoning
  • Cytarabine overdose
  • Dacarbazine overdose
  • Dacarbazine poisoning
  • Dactinomycin overdose
  • Doxorubicin overdose
  • Doxorubicin poisoning
  • Epirubicin overdose
  • Epirubicin poisoning
  • Estramustine overdose
  • Estramustine poisoning
  • Ethoglucid overdose
  • Ethoglucid poisoning
  • Etoposide overdose
  • Etoposide poisoning
  • Fludarabine overdose
  • Fludarabine poisoning
  • Fluorouracil overdose
  • Hydroxycarbamide overdose
  • Hydroxycarbamide poisoning
  • Idarubicin overdose
  • Idarubicin poisoning
  • Ifosfamide overdose
  • Ifosfamide poisoning
  • Intentional aclarubicin overdose
  • Intentional aclarubicin poisoning
  • Intentional aminoglutethimide overdose
  • Intentional aminoglutethimide poisoning
  • Intentional amsacrine overdose
  • Intentional amsacrine poisoning
  • Intentional azathioprine overdose
  • Intentional azathioprine poisoning
  • Intentional bleomycin overdose
  • Intentional bleomycin poisoning
  • Intentional busulfan overdose
  • Intentional busulfan poisoning
  • Intentional carboplatin overdose
  • Intentional carboplatin poisoning
  • Intentional carmustine overdose
  • Intentional carmustine poisoning
  • Intentional chlorambucil overdose
  • Intentional chlorambucil poisoning
  • Intentional chlormethine overdose
  • Intentional chlormethine poisoning
  • Intentional cisplatin overdose
  • Intentional cisplatin poisoning
  • Intentional crisantaspase overdose
  • Intentional crisantaspase poisoning
  • Intentional cyclophosphamide overdose
  • Intentional cyclophosphamide poisoning
  • Intentional cyclosporin overdose
  • Intentional cyclosporin poisoning
  • Intentional cytarabine overdose
  • Intentional cytarabine poisoning
  • Intentional dacarbazine overdose
  • Intentional dacarbazine poisoning
  • Intentional dactinomycin overdose
  • Intentional dactinomycin poisoning
  • Intentional daunorubicin poisoning
  • Intentional doxorubicin overdose
  • Intentional doxorubicin poisoning
  • Intentional epirubicin overdose
  • Intentional epirubicin poisoning
  • Intentional estramustine overdose
  • Intentional estramustine poisoning
  • Intentional ethoglucid overdose
  • Intentional ethoglucid poisoning
  • Intentional etoposide overdose
  • Intentional etoposide poisoning
  • Intentional fludarabine overdose
  • Intentional fludarabine poisoning
  • Intentional fluorouracil overdose
  • Intentional fluorouracil poisoning
  • Intentional hydroxycarbamide overdose
  • Intentional hydroxycarbamide poisoning
  • Intentional idarubicin overdose
  • Intentional idarubicin poisoning
  • Intentional ifosfamide overdose
  • Intentional ifosfamide poisoning
  • Intentional lomustine overdose
  • Intentional lomustine poisoning
  • Intentional melphalan overdose
  • Intentional melphalan poisoning
  • Intentional mercaptopurine overdose
  • Intentional mercaptopurine poisoning
  • Intentional methotrexate overdose
  • Intentional methotrexate poisoning
  • Intentional mitobronitol overdose
  • Intentional mitobronitol poisoning
  • Intentional mitomycin overdose
  • Intentional mitomycin poisoning
  • Intentional mitoxantrone overdose
  • Intentional mitoxantrone poisoning
  • Intentional paclitaxel overdose
  • Intentional paclitaxel poisoning
  • Intentional pentostatin overdose
  • Intentional pentostatin poisoning
  • Intentional piperazine overdose
  • Intentional piperazine poisoning
  • Intentional plicamycin overdose
  • Intentional plicamycin poisoning
  • Intentional procarbazine overdose
  • Intentional procarbazine poisoning
  • Intentional razoxane overdose
  • Intentional razoxane poisoning
  • Intentional thioguanine overdose
  • Intentional thioguanine poisoning
  • Intentional thiotepa overdose
  • Intentional thio-TEPA poisoning
  • Intentional treosulfan overdose
  • Intentional treosulfan poisoning
  • Intentional vinblastine overdose
  • Intentional vinblastine poisoning
  • Intentional vincristine overdose
  • Intentional vincristine poisoning
  • Intentional vindesine overdose
  • Intentional vindesine poisoning
  • Lomustine overdose
  • Lomustine poisoning
  • Melphalan overdose
  • Melphalan poisoning
  • Mercaptopurine overdose
  • Methotrexate overdose
  • Methotrexate poisoning
  • Mitobronitol overdose
  • Mitobronitol poisoning
  • Mitomycin overdose
  • Mitoxantrone overdose
  • Mitoxantrone poisoning
  • Nitrosurea overdose
  • Nitrosurea overdose
  • Nitrosurea poisoning
  • Nitrosurea poisoning
  • Paclitaxel overdose
  • Paclitaxel poisoning
  • Pentostatin overdose
  • Pentostatin poisoning
  • Plicamycin overdose
  • Plicamycin poisoning
  • Poisoning by actinomycin
  • Poisoning by azathioprine
  • Poisoning by bleomycin
  • Poisoning by busulfan
  • Poisoning by chlorambucil
  • Poisoning by cyclophosphamide
  • Poisoning by cytarabine
  • Poisoning by daunorubicin
  • Poisoning by fluorouracil
  • Poisoning by mercaptopurine
  • Poisoning by mitomycin
  • Poisoning by thiotepa
  • Procarbazine overdose
  • Procarbazine poisoning
  • Razoxane overdose
  • Razoxane poisoning
  • Thioguanine overdose
  • Thioguanine poisoning
  • Thiotepa overdose
  • Treosulfan overdose
  • Treosulfan poisoning
  • Triazene antineoplastic overdose
  • Triazene antineoplastic poisoning
  • Vinblastine overdose
  • Vinblastine poisoning
  • Vincristine overdose
  • Vincristine poisoning
  • Vindesine overdose
  • Vindesine poisoning

Diagnostic Related Groups

The ICD-10 code T45.1X2A is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2019 through 09/30/2020.


Convert T45.1X2A to ICD-9

  • 963.1 - Pois-antineopl/immunosup (Combination Flag)
  • E950.4 - Poison-drug/medicin NEC (Combination Flag)

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Primarily systemic and hematological agents, NEC (T45)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include

  • Prescription or over-the-counter medicines taken in doses that are too high
  • Overdoses of illegal drugs
  • Carbon monoxide from gas appliances
  • Household products, such as laundry powder or furniture polish
  • Pesticides
  • Indoor or outdoor plants
  • Metals such as lead and mercury

The effects of poisoning range from short-term illness to brain damage, coma, and death. To prevent poisoning it is important to use and store products exactly as their labels say. Keep dangerous products where children can't get to them. Treatment for poisoning depends on the type of poison. If you suspect someone has been poisoned, call your local poison control center at 1-800-222-1222 right away.

[Learn More]


What is self-harm?

Self-harm, or self-injury, is when a person hurts his or her own body on purpose. The injuries may be minor, but sometimes they can be severe. They may leave permanent scars or cause serious health problems. Some examples are

  • Cutting yourself (such as using a razor blade, knife, or other sharp object to cut your skin)
  • Punching yourself or punching things (like a wall)
  • Burning yourself with cigarettes, matches, or candles
  • Pulling out your hair
  • Poking objects through body openings
  • Breaking your bones or bruising yourself

Self-harm is not a mental disorder. It is a behavior - an unhealthy way to cope with strong feelings. However, some of the people who harm themselves do have a mental disorder.

People who harm themselves are usually not trying to kill themselves. But they are at higher risk of attempting suicide if they do not get help.

Why do people harm themselves?

There are different reasons why people harm themselves. Often, they have trouble coping and dealing with their feelings. They harm themselves to try to

  • Make themselves feel something, when they feel empty or numb inside
  • Block upsetting memories
  • Show that they need help
  • Release strong feelings that overwhelm them, such as anger, loneliness, or hopelessness
  • Punish themselves
  • Feel a sense of control

Who is at risk for self-harm?

There are people of all ages who harm themselves, but it usually starts in the teen or early adult years. Self-harm is more common in people who

  • Were abused or went through a trauma as children
  • Have mental disorders, such as
    • Depression
    • Eating disorders
    • Post-traumatic stress disorder
    • Certain personality disorders
  • Abuse drugs or alcohol
  • Have friends who self-harm
  • Have low self-esteem

What are the signs of self-harm?

Signs that someone may be hurting themselves include

  • Having frequent cuts, bruises, or scars
  • Wearing long sleeves or pants even in hot weather
  • Making excuses about injuries
  • Having sharp objects around for no clear reason

How can I help someone who self-harms?

If someone you know is self-harming, it is important not to be judgmental. Let that person know that you want to help. If the person is a child or teenager, ask him or her to talk to a trusted adult. If he or she won't do that, talk to a trusted adult yourself. If the person who is self-harming is an adult, suggest mental health counseling.

What the treatments are for self-harm?

There are no medicines to treat self-harming behaviors. But there are medicines to treat any mental disorders that the person may have, such as anxiety and depression. Treating the mental disorder may weaken the urge to self-harm.

Mental health counseling or therapy can also help by teaching the person

  • Problem-solving skills
  • New ways to cope with strong emotions
  • Better relationship skills
  • Ways to strengthen self-esteem

If the problem is severe, the person may need more intensive treatment in a psychiatric hospital or a mental health day program.

[Learn More]