ICD-10-CM Code T45.0X5

Adverse effect of antiallergic and antiemetic drugs

Version 2020 Replaced Code Non-Billable Code Adverse Effect

Not Valid for Submission

T45.0X5 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of antiallergic and antiemetic drugs. The code is NOT valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code T45.0X5 might also be used to specify conditions or terms like 5-ht3-receptor antagonist adverse reaction, acrivastine adverse reaction, adverse reaction to antihistamines, antazoline adverse reaction, antiallergenic drug adverse reaction, antiemetic adverse reaction, etc

ICD-10:T45.0X5
Short Description:Adverse effect of antiallergic and antiemetic drugs
Long Description:Adverse effect of antiallergic and antiemetic drugs

Consider the following ICD-10 codes with a higher level of specificity:

  • T45.0X5A - Adverse effect of antiallergic and antiemetic drugs, initial encounter
  • T45.0X5D - Adverse effect of antiallergic and antiemetic drugs, subsequent encounter
  • T45.0X5S - Adverse effect of antiallergic and antiemetic drugs, sequela

Replaced Code

This code was replaced in the 2020 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2019. This code was replaced for the FY 2020 (October 1, 2019 - September 30, 2020).

  • K59.03 - Drug induced constipation

Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • 5-HT3-receptor antagonist adverse reaction
  • Acrivastine adverse reaction
  • Adverse reaction to antihistamines
  • Antazoline adverse reaction
  • Antiallergenic drug adverse reaction
  • Antiemetic adverse reaction
  • Astemizole adverse reaction
  • Azatadine adverse reaction
  • Azelastine adverse reaction
  • Brompheniramine adverse reaction
  • Cetirizine adverse reaction
  • Chlorphenamine adverse reaction
  • Cinnarizine adverse reaction
  • Clemastine adverse reaction
  • Cough suppressant adverse reaction
  • Cromoglycate and related antiallergenic adverse reaction
  • Cyclizine adverse reaction
  • Cyproheptadine adverse reaction
  • Dimenhydrinate adverse reaction
  • Dimethindene adverse reaction
  • Diphenhydramine adverse reaction
  • Diphenylpyraline adverse reaction
  • Domperidone adverse reaction
  • H1 antihistamine adverse reaction
  • Ketotifen adverse reaction
  • Lodoxamide adverse reaction
  • Loratadine adverse reaction
  • Mebhydrolin adverse reaction
  • Meclozine hydrochloride adverse reaction
  • Mepyramine adverse reaction
  • Metoclopramide adverse reaction
  • Oxatomide adverse reaction
  • Phenindamine adverse reaction
  • Pheniramine adverse reaction
  • Terfenadine adverse reaction
  • Topical antihistamine adverse reaction
  • Triprolidine adverse reaction
  • Xanthine adverse reaction

Code Classification

  • Injury, poisoning and certain other consequences of external causes (S00–T98)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50)
      • Primarily systemic and hematological agents, NEC (T45)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Table of Drugs and Chemicals

The code T45.0X5 is included in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. Use as many codes as necessary to describe all reported drugs, medicinal or chemical substances.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
self-harm
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AcrivastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AlizaprideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antazolin (e)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antiallergic NECT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antiemetic drugT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AntihistamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antinausea drugT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AntistineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Antivertigo drugT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AstemizoleT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AzatadineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
AzelastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BamipineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BenadrylT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Benzhydramine (chloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BenzquinamideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Bisulepin (hydrochloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BonineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BromazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BromodiphenhydramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BrompheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
BuclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CarbinoxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Cerium oxalateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Cerous oxalateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CetirizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CetoximeT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorcyclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChloropyramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChloropyrileneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorothenT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorphenamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorpheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ChlorphenoxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Chlor-TrimetonT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CinnarizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ClemastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ClemizoleT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Clemizole
  »penicillin
T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ClorfenamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CyclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
CyproheptadineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DeptropineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DexbrompheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DexchlorpheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DibenzheptropineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DifenidolT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimenhydrinateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimetaneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimethindeneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DimetindeneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DiphenhydramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DiphenidolT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DiphenylpyralineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DomperidoneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DoxylamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
DramamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
EmbramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
GranisetronT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
HomochlorcyclizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
IsothipendylT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
KetotifenT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Levocabastine (hydrochloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
LoratidineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MarezineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MebhydrolinT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Meclizine (hydrochloride)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MeclozineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MephenhydramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MepyramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MethaphenileneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MethapyrileneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MetoclopramideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
MoxastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
NytolT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
OndansetronT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
OxatomideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Percogesic [See Also: acetaminophen]T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PeriactinT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PhenindamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PheniramineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PhenyltoloxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PimethixeneT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PipamazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PipoxizineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PiprinhydrinateT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PropiomazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyrathiazineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyribenzamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyrilamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
PyrrobutamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
RotoxamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
SetastineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Sleep-ezeT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
SominexT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TerfenadineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
ThenyldiamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Thonzylamine (systemic)T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
Thonzylamine (systemic)
  »mucosal decongestant
T45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TiganT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TranilastT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TrimethobenzamideT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TrimetonT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TripelennamineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TriprolidineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6
TritoqualineT45.0X1T45.0X2T45.0X3T45.0X4T45.0X5T45.0X6

Information for Patients


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions.

One problem is interactions, which may occur between

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as ginkgo and blood thinners
  • Drugs and diseases, such as aspirin and peptic ulcers

Interactions can change the actions of one or both drugs. The drugs might not work, or you could get side effects.

Side effects are unwanted effects caused by the drugs. Most are mild, such as a stomach aches or drowsiness, and go away after you stop taking the drug. Others can be more serious.

Drug allergies are another type of reaction. They can be mild or life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is more rare.

When you start a new prescription or over-the-counter medication, make sure you understand how to take it correctly. Know which other medications and foods you need to avoid. Ask your health care provider or pharmacist if you have questions.


[Learn More]