2027 ICD-10-CM Diagnosis Code E78.79Other disorders of bile acid and cholesterol metabolism
ICD-10-CM Codes›E00–E89›E70-E88›E78
- Billable — Valid for Submission
- Chronic Condition
E78.79 is a billable ICD-10-CM diagnosis code for other disorders of bile acid and cholesterol metabolism. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 642. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.
E78.79 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 47 for payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
E78.79 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model, but it maps to payment categories in the other CMS models shown below.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Bile acid CoA ligase deficiency and defective amidation
- Bile acid malabsorption syndrome
- Bile acid malabsorption syndrome type I
- Bile acid malabsorption syndrome type II
- Cholesterol tophus
- Deficiency of cholate-CoA ligase
- Deficiency of cholesterol esterase
- Deficiency of cholesterol oxidase
- Delta-4-3-oxosteroid-5-beta-reductase deficiency
- Desmosterolosis
- Disorder of cholesterol catabolism
- Disorder of cholesterol metabolism
- Disorder of cholesterol synthesis
- Familial hypercholanemia
- Intestinal malabsorption
- Intestinal malabsorption due to bile acid synthesis defect
- Lathosterolosis
- Neonatal osteosclerotic dysplasia
- Synthetic defect of bile acids
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E78.79: its own notes plus those printed at E78.7, E78, block E70-E88, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- Niemann-Pick disease type C (E75.242)
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- Ehlers-Danlos syndromes (Q79.6-)
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name E78.79, its category, or a range that includes it.
Excludes2 2
These codes carry an Excludes2 note naming E78.79: its condition is not part of those codes, and both may be reported when the patient has both.
- E88.0 Disorders of plasma-protein metabolism, not elsewhere classifieddisorder of lipoprotein metabolism (E78.-) names E78.-, which includes this code
- Block R70-R79 Abnormal findings on examination of blood, without diagnosisabnormalities of lipids (E78.-) names E78.-, which includes this code
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disorder (of) See Also: Disease;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Lipid Metabolism Disorders
Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system (enzymes) break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E78.79 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E78.79Overview
What is the ICD-10 code for other disorders of bile acid and cholesterol metabolism?
The ICD-10-CM code for other disorders of bile acid and cholesterol metabolism is E78.79 (sometimes written as E7879). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E78.79 (Disorders of bile acid and cholesterol metabolism) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other disorders of bile acid and cholesterol metabolism on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E78.79 group to?
When other disorders of bile acid and cholesterol metabolism is the principal diagnosis on an inpatient stay, it groups to MS-DRG 642 (inborn and Other Disorders of Metabolism), which carries a relative weight of 1.3226. Higher weights mean higher Medicare reimbursement.
Can E78.79 be reported with E75.242?
Not as a rule. The Excludes1 note at E78.7, which applies to E78.79, lists "Niemann-Pick disease type C (E75.242)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of E78.79?
Under the General Equivalence Mappings, other disorders of bile acid and cholesterol metabolism converts to ICD-9-CM 272.8 (lipoid metabol dis NEC). The mapping is approximate, so confirm the match fits the documentation.
Does E78.79 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage: E78.79 maps to no category in the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 47 (Disorders of Lipoid Metabolism).
